Comparative Efficacies of Linezolid vs. Tedizolid in an Experimental Murine Model of Vancomycin-Resistant Enterococcal (VRE) Bacteremia

by Wessam Abdelhady, Nagendra N. Mishra, Nagendra N. Mishra
Published 2019-02-01

Differential Adaptations of Methicillin-Resistant Staphylococcus aureus to Serial In Vitro Passage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid...

by Nagendra N. Mishra, Aileen Rubio, Cynthia C. Nast, Arnold S. Bayer
Published 2012-01-01

Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in <i>Streptococcus mitis-oralis</i>

by Michael R. Yeaman, Liana C. Chan, Nagendra N. Mishra, Arnold S. Bayer
Published 2021-04-01

Strain-Specific Adaptations of <i>Streptococcus mitis-oralis</i> to Serial In Vitro Passage in Daptomycin (DAP): Genotypic and Phenotypic Characteristics

by Nagendra N. Mishra, Truc T. Tran, Cesar A. Arias, Ravin Seepersaud, Paul M. Sullam, Arnold S. Bayer
Published 2020-08-01

Activity of the Lactate Dehydrogenase Inhibitor Oxamic Acid against the Fermentative Bacterium <i>Streptococcus mitis/oralis</i>: Bactericidal Effects and Prevention of Daptomycin...

by Razieh Kebriaei, Arnold S. Bayer, Christian K. Lapitan, Michael J. Rybak, Greg A. Somerville, Nagendra N. Mishra
Published 2022-10-01

Proteomic and Membrane Lipid Correlates of Re-duced Host Defense Peptide Susceptibility in a <em>snoD</em> Mutant of <em>Staphylococcus aureus</em>

by Christian Kohler, Richard A. Proctor, Arnold S. Bayer, Michael R. Yeaman, Michael Lalk, Susanne Engelmann, Nagendra N. Mishra
Published 2019-09-01

Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.

by Nagendra N Mishra, Arnold S Bayer, Truc T Tran, Yousif Shamoo, Eugenia Mileykovskaya, William Dowhan, Ziqiang Guan, Cesar A Arias
Published 2012-01-01

Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis

by Allison Parrett, Joseph M. Reed, Stewart G. Gardner, Nagendra N. Mishra, Arnold S. Bayer, Robert Powers, Greg A. Somerville
Published 2020-06-01

Cell Membrane Adaptations Mediate β-Lactam-Induced Resensitization of Daptomycin-Resistant (DAP-R) <i>Staphylococcus aureus</i> In Vitro

by Nagendra N. Mishra, Arnold S. Bayer, Sarah L. Baines, Ashleigh S. Hayes, Benjamin P. Howden, Christian K. Lapitan, Cassandra Lew, Warren E. Rose
Published 2021-05-01

The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion.

by Christoph M Ernst, Petra Staubitz, Nagendra N Mishra, Soo-Jin Yang, Gabriele Hornig, Hubert Kalbacher, Arnold S Bayer, Dirk Kraus, Andreas Peschel
Published 2009-11-01

Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance

by Christoph M. Ernst, Christoph J. Slavetinsky, Sebastian Kuhn, Janna N. Hauser, Mulugeta Nega, Nagendra N. Mishra, Cordula Gekeler, Arnold S. Bayer, Andreas Peschel
Published 2018-12-01

Membrane Phenotypic, Metabolic and Genotypic Adaptations of <i>Streptococcus oralis</i> Strains Destined to Rapidly Develop Stable, High-Level Daptomycin Resistance during Daptomyc...

by Nagendra N. Mishra, Rodrigo de Paula Baptista, Truc T. Tran, Christian K. Lapitan, Cristina Garcia-de-la-Maria, Jose M. Miró, Richard A. Proctor, Arnold S. Bayer
Published 2023-06-01

Phenotypic and genotypic characterization of daptomycin-resistant methicillin-resistant Staphylococcus aureus strains: relative roles of mprF and dlt operons.

by Nagendra N Mishra, Arnold S Bayer, Christopher Weidenmaier, Timo Grau, Stefanie Wanner, Stefania Stefani, Viviana Cafiso, Taschia Bertuccio, Michael R Yeaman, Cynthia C Nast, Soo-Jin Yang
Published 2014-01-01

Increased cell wall teichoic acid production and D-alanylation are common phenotypes among daptomycin-resistant methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates...

by Ute Bertsche, Soo-Jin Yang, Daniel Kuehner, Stefanie Wanner, Nagendra N Mishra, Tobias Roth, Mulugeta Nega, Alexander Schneider, Christoph Mayer, Timo Grau, Arnold S Bayer, Christopher Weidenmaier
Published 2013-01-01

Emergence of daptomycin resistance in daptomycin-naïve rabbits with methicillin-resistant Staphylococcus aureus prosthetic joint infection is associated with resistance to host def...

by Nagendra N Mishra, Soo-Jin Yang, Liang Chen, Claudette Muller, Azzam Saleh-Mghir, Sebastian Kuhn, Andreas Peschel, Michael R Yeaman, Cynthia C Nast, Barry N Kreiswirth, Anne-Claude Crémieux, Arnold S Bayer
Published 2013-01-01

Daptomycin-Resistant <named-content content-type="genus-species">Enterococcus faecalis</named-content> Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Me...

by Truc T. Tran, Diana Panesso, Nagendra N. Mishra, Eugenia Mileykovskaya, Ziqianq Guan, Jose M. Munita, Jinnethe Reyes, Lorena Diaz, George M. Weinstock, Barbara E. Murray, Yousif Shamoo, William Dowhan, Arnold S. Bayer, Cesar A. Arias
Published 2013-08-01