Improved neuroprotection using miglustat, curcumin and ibuprofen as a triple combination therapy in Niemann–Pick disease type C1 mice

by Ian M. Williams, Kerri-Lee Wallom, David A. Smith, Nada Al Eisa, Claire Smith, Frances M. Platt
Published 2014-07-01

Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C [version 1; peer review: 2 approved]

by David Smith, Nada Al Eisa, Isabelle Williams, Wolfram Haller, Sumeet Pandey, Alicia Chan, Hien Quoc Huynh, Holm H. Uhlig, Ruth Bettels, Gesche Düeker, Chinenye R. Dike, Laurent Peyrin-Biroulet, Thorsten Marquardt, Catherine DeGeeter, Frances M. Platt, Nick Platt, Tobias Schwerd
Published 2022-01-01

Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.

by Elena-Raluca Nicoli, Nada Al Eisa, Celine V M Cluzeau, Christopher A Wassif, James Gray, Kathryn R Burkert, David A Smith, Lauren Morris, Stephanie M Cologna, Cody J Peer, Tristan M Sissung, Constantin-Daniel Uscatu, William D Figg, William J Pavan, Charles H Vite, Forbes D Porter, Frances M Platt
Published 2016-01-01

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 1; referees: 2 approved, 1 approved with reservations]

by Paul Fineran, Emyr Lloyd-Evans, Nathan A. Lack, Nick Platt, Lianne C. Davis, Anthony J. Morgan, Doris Höglinger, Raju Venkata V. Tatituri, Simon Clark, Ian M. Williams, Patricia Tynan, Nada Al Eisa, Evgeniya Nazarova, Ann Williams, Antony Galione, Daniel S. Ory, Gurdyal S. Besra, David G. Russell, Michael B. Brenner, Edith Sim, Frances M. Platt
Published 2016-11-01

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 2; referees: 2 approved, 2 approved with reservations]

by Paul Fineran, Emyr Lloyd-Evans, Nathan A. Lack, Nick Platt, Lianne C. Davis, Anthony J. Morgan, Doris Höglinger, Raju Venkata V. Tatituri, Simon Clark, Ian M. Williams, Patricia Tynan, Nada Al Eisa, Evgeniya Nazarova, Ann Williams, Antony Galione, Daniel S. Ory, Gurdyal S. Besra, David G. Russell, Michael B. Brenner, Edith Sim, Frances M. Platt
Published 2017-06-01