Special Issue: “James D. McChesney, Vision, Passion and Leadership in the Development of Plant-Derived Natural Products”

by Larry A. Walker, N. P. Dhammika Nanayakkara
Published 2021-12-01

Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B

by Narayan D. Chaurasiya, Haining Liu, Robert J. Doerksen, N. P. Dhammika Nanayakkara, Larry A. Walker, Babu L. Tekwani
Published 2021-04-01

Novel bioassay for the discovery of inhibitors of the 2-C-methyl-D-erythritol 4-phosphate (MEP) and terpenoid pathways leading to carotenoid biosynthesis.

by Natália Corniani, Edivaldo D Velini, Ferdinando M L Silva, N P Dhammika Nanayakkara, Matthias Witschel, Franck E Dayan
Published 2014-01-01

Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, <i>Nemania</i> sp. UM10M, Isolated from a Diseased <i>Torreya taxifolia</i> Leaf

by Mallika Kumarihamy, Daneel Ferreira, Edward M. Croom, Rajnish Sahu, Babu L. Tekwani, Stephen O. Duke, Shabana Khan, Natascha Techen, N. P. Dhammika Nanayakkara
Published 2019-02-01

Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes

by Pius S. Fasinu, N. P. Dhammika Nanayakkara, Yan-Hong Wang, Narayan D. Chaurasiya, H. M. Bandara Herath, James D. McChesney, Bharathi Avula, Ikhlas Khan, Babu L. Tekwani, Larry A. Walker
Published 2019-01-01

Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice

by Pius S. Fasinu, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan‑Hong Wang, H. M. T. Bandara Herath, Bharathi Avula, James D. McChesney, David Jollow, Larry A. Walker, Babu L. Tekwani
Published 2022-02-01

NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation

by Timothy Hamerly, Timothy Hamerly, Rebecca E. Tweedell, Rebecca E. Tweedell, Bernadette Hritzo, Vincent O. Nyasembe, Babu L. Tekwani, N. P. Dhammika Nanayakkara, Larry A. Walker, Rhoel R. Dinglasan, Rhoel R. Dinglasan
Published 2019-10-01

Synthesis and Inhibitory Activity of Machaeridiol-Based Novel Anti-MRSA and Anti-VRE Compounds and Their Profiling for Cancer-Related Signaling Pathways

by Mallika Kumarihamy, Siddharth Tripathi, Premalatha Balachandran, Bharathi Avula, Jianping Zhao, Mei Wang, Maria M. Bennett, Jin Zhang, Mary A. Carr, K. Michael Lovell, Ocean I. Wellington, Mary E. Marquart, N. P. Dhammika Nanayakkara, Ilias Muhammad
Published 2022-10-01

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quad...

by Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, Pius Fasinu, N. P. Dhammika Nanayakkara, H. M. T. Bhandara Herath, Yan-Hong Wang, Ji-Yeong Bae, Shabana I. Khan, Mahmoud A. Elsohly, James D. McChesney, Peter A. Zimmerman, Ikhlas A. Khan, Larry A. Walker
Published 2018-08-01

Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration

by Washim Khan, Yan-Hong Wang, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, H. M. Bandara Herath, Kerri A. Harrison, Gray Dale, Donald A. Stanford, Eric P. Dahl, James D. McChesney, Waseem Gul, Mahmoud A. ElSohly, Mahmoud A. ElSohly, Mahmoud A. ElSohly, David Jollow, Babu L. Tekwani, Larry A. Walker
Published 2023-01-01