ApoE4-Driven Accumulation of Intraneuronal Oligomerized Aβ42 following Activation of the Amyloid Cascade In Vivo Is Mediated by a Gain of Function

by Lia Zepa, Moran Frenkel, Haim Belinson, Zehavit Kariv-Inbal, Rakez Kayed, Eliezer Masliah, Daniel M. Michaelson
Published 2011-01-01

ER-alpha-cDNA as part of a bicistronic transcript gives rise to high frequency, long term, receptor expressing cell clones.

by Michal Shenfeld, Yafit Hachmo, Moran Frenkel, Naomi Dafni, Michael Boettcher, Joerg D Hoheisel, Iris Dotan, Dan Canaani
Published 2012-01-01

Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies.

by Ronit Shaltiel-Karyo, Moran Frenkel-Pinter, Nirit Egoz-Matia, Anat Frydman-Marom, Deborah E Shalev, Daniel Segal, Ehud Gazit
Published 2010-01-01

A Novel, Sensitive Assay for Behavioral Defects in Parkinson's Disease Model Drosophila

by Ronit Shaltiel-Karyo, Dan Davidi, Yotam Menuchin, Moran Frenkel-Pinter, Mira Marcus-Kalish, John Ringo, Ehud Gazit, Daniel Segal
Published 2012-01-01

Thioesters provide a plausible prebiotic path to proto-peptides

by Moran Frenkel-Pinter, Marcos Bouza, Facundo M. Fernández, Luke J. Leman, Loren Dean Williams, Nicholas V. Hud, Aikomari Guzman-Martinez
Published 2022-05-01

Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions

by Moran Frenkel-Pinter, Kaitlin C. Jacobson, Jonathan Eskew-Martin, Jay G. Forsythe, Martha A. Grover, Loren Dean Williams, Nicholas V. Hud
Published 2022-02-01

Mutually stabilizing interactions between proto-peptides and RNA

by Moran Frenkel-Pinter, Jay W. Haynes, Ahmad M. Mohyeldin, Martin C, Alyssa B. Sargon, Anton S. Petrov, Ramanarayanan Krishnamurthy, Nicholas V. Hud, Loren Dean Williams, Luke J. Leman
Published 2020-06-01