Blockade of the SRC/STAT3/BCL-2 Signaling Axis Sustains the Cytotoxicity in Human Colorectal Cancer Cell Lines Induced by Dehydroxyhispolon Methyl Ether

by Ya-Chu Hsieh, Yuan-Chang Dai, Kur-Ta Cheng, Wei-Ting Yang, Modukuri V. Ramani, Gottumukkala V. Subbaraju, Yi-Ju Chen, Chia-Che Chang
Published 2023-09-01

Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis

by Hueng-Chuen Fan, Ya-Chu Hsieh, Li-Hsuan Li, Ching-Chin Chang, Karolína Janoušková, Modukuri V. Ramani, Gottumukkala V. Subbaraju, Kur-Ta Cheng, Chia-Che Chang
Published 2020-11-01

Toxicity and Antigenotoxic Effect of Hispolon Derivatives: Role of Structure in Modulating Cellular Redox State and Thioredoxin Reductase

by Pogakula Chethna, Shruti S. Iyer, Vishwa V. Gandhi, Amit Kunwar, Beena G. Singh, Atanu Barik, Neduri V. Balaji, Modukuri V. Ramani, Gottumukkala V. Subbaraju, K. Indira Priyadarsini
Published 2018-06-01

Methoxyhispolon Methyl Ether, a Hispolon Analog, Thwarts the SRC/STAT3/BCL-2 Axis to Provoke Human Triple-Negative Breast Cancer Cell Apoptosis In Vitro

by Chih-Pin Liao, Ya-Chu Hsieh, Chien-Hsing Lu, Wen-Chi Dai, Wei-Ting Yang, Kur-Ta Cheng, Modukuri V. Ramani, Gottumukkala V. Subbaraju, Chia-Che Chang
Published 2023-10-01