Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis

by Joanna E. Pankiewicz, Jenny R. Diaz, Mitchell Martá-Ariza, Anita M. Lizińczyk, Leor A. Franco, Martin J. Sadowski
Published 2020-09-01

Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype

by Joanna E. Pankiewicz, Anita M. Lizińczyk, Leor A. Franco, Jenny R. Diaz, Mitchell Martá-Ariza, Martin J. Sadowski
Published 2021-09-01

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model

by Fernando Goñi, Mitchell Martá-Ariza, Krystal Herline, Daniel Peyser, Allal Boutajangout, Pankaj Mehta, Eleanor Drummond, Frances Prelli, Thomas Wisniewski
Published 2018-01-01

The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome

by Eleanor Drummond, Tomas Kavanagh, Geoffrey Pires, Mitchell Marta-Ariza, Evgeny Kanshin, Shruti Nayak, Arline Faustin, Valentin Berdah, Beatrix Ueberheide, Thomas Wisniewski
Published 2022-04-01

Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline

by Shan Liu, Shinae Park, Grant Allington, Frances Prelli, Yanjie Sun, Mitchell Martá-Ariza, Henrieta Scholtzova, Goutam Biswas, Bernard Brown, Philip B. Verghese, Pankaj D. Mehta, Yong-Uk Kwon, Thomas Wisniewski
Published 2017-08-01

Apolipoprotein E4 Effects a Distinct Transcriptomic Profile and Dendritic Arbor Characteristics in Hippocampal Neurons Cultured in vitro

by Jenny R. Diaz, Mitchell Martá-Ariza, Alireza Khodadadi-Jamayran, Adriana Heguy, Aristotelis Tsirigos, Joanna E. Pankiewicz, Joanna E. Pankiewicz, Patrick M. Sullivan, Patrick M. Sullivan, Martin J. Sadowski, Martin J. Sadowski, Martin J. Sadowski
Published 2022-04-01