Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing

by Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Qi Wang, Jacqueline K. R. Walker, Grace E. Lidgerwood, Kimberley L. Dilworth, Leszek Lisowski, Alice Pébay, Alex W. Hewitt
Published 2020-09-01

Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant

by Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Alice Pébay, Anthony L. Cook, Helena H. Liang, Raymond C.B. Wong, Jamie E. Craig, Guei-Sheung Liu, Sandy S. Hung, Alex W. Hewitt
Published 2019-03-01

Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing

by Fan Li, Fan Li, Kristof Wing, Jiang-Hui Wang, Chi D. Luu, Chi D. Luu, James A. Bender, Jinying Chen, Jinying Chen, Qi Wang, Qinyi Lu, Minh Thuan Nguyen Tran, Kaylene M. Young, Raymond C. B. Wong, Raymond C. B. Wong, Alice Pébay, Alice Pébay, Anthony L. Cook, Sandy S. C. Hung, Sandy S. C. Hung, Guei-Sheung Liu, Guei-Sheung Liu, Alex W. Hewitt, Alex W. Hewitt
Published 2020-09-01