Polycationic peptide R7-G-Aβ25-35 selectively induces cell death in leukemia Jurkat T cells through speedy mitochondrial depolarization, and CASPASE-3 -independent mechanism

by Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo
Published 2022-09-01

(−)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer’s Disease PSEN1 E280A

by Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio
Published 2021-12-01

CANNABIDIOL PROTECTS DOPAMINERGIC NEURONS AGAINST PARAQUAT- AND MANEB-INDUCED CELL DEATH THROUGH SAFEGUARDING DJ-1 CYS106 AND INHIBITING CASPASE 3 INDEPENDENTLY OF CANNABINOID RECE...

by Miguel Mendivil-Perez, Andrea Felizardo-Otalvaro, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo
Published 2023-10-01

CEREBRAL SPHEROIDS DERIVED FROM MENSTRUAL MESENCHYMAL STROMAL CELLS WITH PSEN1 E280A MUTATION REPRODUCES ALZHEIMER’S DISEASE PATHOLOGY AND ARE PROTECTED BY EPIGALLOCATECHIN 3-GALLA...

by Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio
Published 2023-10-01

LRRK2 REGULATES CELL DEATH PROGRESSION RATHER THAN AUTOPHAGIC FLUX IN AN IN VITRO MODEL OF PARKINSON’S DISEASE INDUCED BY CHEMICAL INHIBITION OF GLUCOCEREBROSIDASE.

by Laura Perez Abshana, Miguel Mendivil-Perez, Marlene Jiménez Del Rio, Carlos Vélez Pardo
Published 2023-10-01

ASTROCYTE-LIKE CELLS DERIVED FROM PSEN1 E280A MENSTRUAL MESENCHYMAL STROMAL CELLS SHOW ALTERED TRANSDIFFERENTIATION POTENTIAL AND FUNCTIONALITY IN AN AMYLOID BETA-INDEPENDENT FASHI...

by Natalia Quiroz Correa, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio
Published 2023-10-01

PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent

by Miguel Mendivil-Perez, Carlos Velez-Pardo, Francisco Lopera, Kenneth S. Kosik, Marlene Jimenez-Del-Rio
Published 2023-05-01

Rotenone Blocks the Glucocerebrosidase Enzyme and Induces the Accumulation of Lysosomes and Autophagolysosomes Independently of LRRK2 Kinase in HEK-293 Cells

by Laura Patricia Perez-Abshana, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio
Published 2023-06-01

Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative s...

by Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Francisco Lopera, Marlene Jimenez-Del-Rio
Published 2020-01-01

MENSTRUAL STROMAL CELL-DERIVED CHOLINERGIC-LIKE NEURONS AND CEREBRAL SPHEROIDS BEARING THE PSEN1 P.ILE416THR VARIANT MIRROR THE TYPICAL NEUROPATHOLOGICAL HALLMARKS OF FAMILIAL ALZH...

by Nicolas Gomez-Sequeda, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Francisco Lopera, Carlos Velez-Pardo
Published 2023-10-01

Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology

by Nicolas Gomez-Sequeda, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Francisco Lopera, Carlos Velez-Pardo
Published 2023-08-01

Melatonin protects rats from radiotherapy-induced small intestine toxicity.

by Beatriz Fernández-Gil, Ahmed E Abdel Moneim, Francisco Ortiz, Ying-Qiang Shen, Viviana Soto-Mercado, Miguel Mendivil-Perez, Ana Guerra-Librero, Darío Acuña-Castroviejo, María M Molina-Navarro, José M García-Verdugo, Ramy K A Sayed, Javier Florido, Juan D Luna, Luis Carlos López, Germaine Escames
Published 2017-01-01