Gene therapy for inherited retinal diseases: exploiting new tools in genome editing and nanotechnology

by Cláudia Carvalho, Luísa Lemos, Pedro Antas, Pedro Antas, Miguel C. Seabra, Miguel C. Seabra
Published 2023-09-01

Thematic review series: Lipid Posttranslational Modifications. Geranylgeranylation of Rab GTPases

by Ka Fai Leung, Rudi Baron, Miguel C. Seabra
Published 2006-03-01

Melanin Transfer in the Epidermis: The Pursuit of Skin Pigmentation Control Mechanisms

by Hugo Moreiras, Miguel C. Seabra, Duarte C. Barral
Published 2021-04-01

Retinal Progression Biomarkers of Early and Intermediate Age-Related Macular Degeneration

by Rita Flores, Ângela Carneiro, Sandra Tenreiro, Miguel C. Seabra
Published 2021-12-01

Bacteria and protozoa differentially modulate the expression of Rab proteins.

by Elsa Seixas, José S Ramalho, Luís J Mota, Duarte C Barral, Miguel C Seabra
Published 2012-01-01

Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia.

by Ingrid P Meschede, Thomas Burgoyne, Tanya Tolmachova, Miguel C Seabra, Clare E Futter
Published 2020-01-01

A role for Na+,K+-ATPase α1 in regulating Rab27a localisation on melanosomes.

by Antonia E G Booth, Abul K Tarafder, Alistair N Hume, Chiara Recchi, Miguel C Seabra
Published 2014-01-01

Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium.

by Silène T Wavre-Shapton, Tanya Tolmachova, Mafalda Lopes da Silva, Clare E Futter, Miguel C Seabra
Published 2013-01-01

Correction: A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes.

by Antonia E G Booth, Abul K Tarafder, Alistair N Hume, Chiara Recchi, Miguel C Seabra
Published 2016-01-01

Correction: Conditional Ablation of the Choroideremia Gene Causes Age-Related Changes in Mouse Retinal Pigment Epithelium.

by Silène T. Wavre-Shapton, Tanya Tolmachova, Mafalda Lopes da Silva, Clare E. Futter, Miguel C. Seabra
Published 2013-01-01

Thousands of rab GTPases for the cell biologist.

by Yoan Diekmann, Elsa Seixas, Marc Gouw, Filipe Tavares-Cadete, Miguel C Seabra, José B Pereira-Leal
Published 2011-10-01

Melanin’s Journey from Melanocytes to Keratinocytes: Uncovering the Molecular Mechanisms of Melanin Transfer and Processing

by Liliana Bento-Lopes, Luís C. Cabaço, João Charneca, Matilde V. Neto, Miguel C. Seabra, Duarte C. Barral
Published 2023-07-01

Choroidal Vascular Impairment in Intermediate Age-Related Macular Degeneration

by Rita Flores, Ângela Carneiro, Guilherme Neri, Ana C. Fradinho, Bruno Quenderra, Maria João Barata, Sandra Tenreiro, Miguel C. Seabra
Published 2022-05-01

Age-Related Changes of the Synucleins Profile in the Mouse Retina

by Sarah Batista Dias, Luísa de Lemos, Luís Sousa, Diogo B. Bitoque, Gabriela Araújo Silva, Miguel C. Seabra, Sandra Tenreiro
Published 2023-01-01

Rab27a Contributes to the Processing of Inflammatory Pain in Mice

by Tilman Gross, Gesine Wack, Katharina M. J. Syhr, Tanya Tolmachova, Miguel C. Seabra, Gerd Geisslinger, Ellen Niederberger, Achim Schmidtko, Wiebke Kallenborn-Gerhardt
Published 2020-06-01

RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditioned Medium

by Luís C. Cabaço, Liliana Bento-Lopes, Matilde V. Neto, Andreia Ferreira, Wanja B.L. Staubli, José S. Ramalho, Miguel C. Seabra, Duarte C. Barral
Published 2022-09-01

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

by Rita Rosado-Ramos, Gonçalo M. Poças, Daniela Marques, Alexandre Foito, David M. Sevillano, Mafalda Lopes-da-Silva, Luís G. Gonçalves, Regina Menezes, Marcel Ottens, Derek Stewart, Alain Ibáñez de Opakua, Markus Zweckstetter, Miguel C. Seabra, César S. Mendes, Tiago Fleming Outeiro, Pedro M. Domingos, Cláudia N. Santos
Published 2023-04-01