Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode.

by Eric Chabrol, Alessandra Nurisso, Antoine Daina, Emilie Vassal-Stermann, Michel Thepaut, Eric Girard, Romain R Vivès, Franck Fieschi
Published 2012-01-01

Adenovirus-Inspired Virus-like-Particles Displaying Melanoma Tumor Antigen Specifically Target Human DC Subsets and Trigger Antigen-Specific Immune Responses

by Solène Besson, David Laurin, Cyrielle Chauvière, Michel Thépaut, Jean-Philippe Kleman, Mylène Pezet, Olivier Manches, Franck Fieschi, Caroline Aspord, Pascal Fender
Published 2022-11-01

X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX

by Isabelle Petit-Hartlein, Annelise Vermot, Michel Thepaut, Anne-Sophie Humm, Florine Dupeux, Jerome Dupuy, Vincent Chaptal, Jose Antonio Marquez, Susan ME Smith, Franck Fieschi
Published 2024-04-01

TETRALEC, Artificial Tetrameric Lectins: A Tool to Screen Ligand and Pathogen Interactions

by Silvia Achilli, João T. Monteiro, Sonia Serna, Sabine Mayer-Lambertz, Michel Thépaut, Aline Le Roy, Christine Ebel, Niels-Christian Reichardt, Bernd Lepenies, Franck Fieschi, Corinne Vivès
Published 2020-07-01

Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

by Alessandra Luchini, Samantha Micciulla, Giacomo Corucci, Krishna Chaithanya Batchu, Andreas Santamaria, Valerie Laux, Tamim Darwish, Robert A. Russell, Michel Thepaut, Isabelle Bally, Franck Fieschi, Giovanna Fragneto
Published 2021-07-01

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist.

by Michel Thépaut, Joanna Luczkowiak, Corinne Vivès, Nuria Labiod, Isabelle Bally, Fátima Lasala, Yasmina Grimoire, Daphna Fenel, Sara Sattin, Nicole Thielens, Guy Schoehn, Anna Bernardi, Rafael Delgado, Franck Fieschi
Published 2021-05-01

The melanoma tumor glyco-code impacts human dendritic cells’ functionality and dictates clinical outcomes

by Eleonora Sosa Cuevas, Eleonora Sosa Cuevas, Benoît Roubinet, Stephane Mouret, Michel Thépaut, Florence de Fraipont, Julie Charles, Franck Fieschi, Franck Fieschi, Ludovic Landemarre, Laurence Chaperot, Laurence Chaperot, Caroline Aspord, Caroline Aspord
Published 2023-02-01

Molecular recognition of Escherichia coli R1-type core lipooligosaccharide by DC-SIGN

by Ferran Nieto-Fabregat, Angela Marseglia, Michel Thépaut, Jean-Philippe Kleman, Massilia Abbas, Aline Le Roy, Christine Ebel, Meriem Maalej, Jean-Pierre Simorre, Cedric Laguri, Antonio Molinaro, Alba Silipo, Franck Fieschi, Roberta Marchetti
Published 2024-02-01

Atomic-Level Dissection of DC-SIGN Recognition of Bacteroides vulgatus LPS Epitopes

by Ferran Nieto-Fabregat, Qian Zhu, Corinne Vivès, Yunqin Zhang, Angela Marseglia, Fabrizio Chiodo, Michel Thépaut, Diksha Rai, Suvarn S. Kulkarni, Flaviana Di Lorenzo, Antonio Molinaro, Roberta Marchetti, Franck Fieschi, Guozhi Xiao, Biao Yu, Alba Silipo
Published 2024-02-01

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein

by Isabelle Bally, Guillaume Drumont, Véronique Rossi, Serafima Guseva, Maiia Botova, Jean-Baptiste Reiser, Michel Thépaut, Sebastian Dergan Dylon, Chantal Dumestre-Pérard, Chantal Dumestre-Pérard, Christine Gaboriaud, Franck Fieschi, Martin Blackledge, Pascal Poignard, Pascal Poignard, Nicole M. Thielens
Published 2024-06-01

Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens

by Rui-Jun Eveline Li, Tim P. Hogervorst, Silvia Achilli, Sven C. M. Bruijns, Sander Spiekstra, Corinne Vivès, Michel Thépaut, Dmitri V. Filippov, Gijs A. van der Marel, Sandra J. van Vliet, Franck Fieschi, Jeroen D. C. Codée, Yvette van Kooyk
Published 2020-07-01

Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen

by Rui-Jun Eveline Li, Tim P. Hogervorst, Silvia Achilli, Sven C. Bruijns, Tim Arnoldus, Corinne Vivès, Chung C. Wong, Michel Thépaut, Nico J. Meeuwenoord, Hans van den Elst, Herman S. Overkleeft, Gijs A. van der Marel, Dmitri V. Filippov, Sandra J. van Vliet, Franck Fieschi, Jeroen D. C. Codée, Yvette van Kooyk
Published 2019-10-01

Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy

by Joyce Woodhouse, Gabriela Nass Kovacs, Nicolas Coquelle, Lucas M. Uriarte, Virgile Adam, Thomas R. M. Barends, Martin Byrdin, Eugenio de la Mora, R. Bruce Doak, Mikolaj Feliks, Martin Field, Franck Fieschi, Virginia Guillon, Stefan Jakobs, Yasumasa Joti, Pauline Macheboeuf, Koji Motomura, Karol Nass, Shigeki Owada, Christopher M. Roome, Cyril Ruckebusch, Giorgio Schirò, Robert L. Shoeman, Michel Thepaut, Tadashi Togashi, Kensuke Tono, Makina Yabashi, Marco Cammarata, Lutz Foucar, Dominique Bourgeois, Michel Sliwa, Jacques-Philippe Colletier, Ilme Schlichting, Martin Weik
Published 2020-02-01