Successful generation of primary virus-specific and anti-tumor T-cell responses from the naïve donor T-cell repertoire is determined by the balance between antigen-specific precurs...

by Inge Jedema, Marian van de Meent, Jeanette Pots, Michel G.D. Kester, Martha T. van der Beek, J.H. Frederik Falkenburg
Published 2011-08-01

Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy

by Marieke Griffioen, Esther H.M. van Egmond, Michel G.D. Kester, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Published 2009-09-01

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo

by Soley Thordardottir, Nicolaas Schaap, Elja Louer, Michel G. D. Kester, J. H. Frederik Falkenburg, Joop Jansen, Timothy R. D. Radstake, Willemijn Hobo, Harry Dolstra
Published 2017-03-01

High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations.

by Pleun Hombrink, Sine R Hadrup, Arne Bakker, Michel G D Kester, J H Frederik Falkenburg, Peter A von dem Borne, Ton N M Schumacher, Mirjam H M Heemskerk
Published 2011-01-01

Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity

by Marieke Griffioen, M. Willy Honders, Edith D. van der Meijden, Simone A.P. van Luxemburg-Heijs, Ellie G.A. Lurvink, Michel G.D. Kester, Cornelis A.M. van Bergen, J.H. Frederik Falkenburg
Published 2012-08-01

Promiscuous binding of invariant chain-derived CLIP peptide to distinct HLA-I molecules revealed in leukemic cells.

by Marvin M van Luijn, Arjan A van de Loosdrecht, Margit H Lampen, Peter A van Veelen, Adri Zevenbergen, Michel G D Kester, Arnoud H de Ru, Gert J Ossenkoppele, Thorbald van Hall, S Marieke van Ham
Published 2012-01-01

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

by Marieke Griffioen, H.M. Esther van Egmond, Helen Barnby-Porritt, Menno A.W.G. van der Hoorn, Renate S. Hagedoorn, Michel G.D. Kester, Nikolai Schwabe, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Published 2008-10-01

Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity

by Aicha Laghmouchi, Michel G. D. Kester, Conny Hoogstraten, Lois Hageman, Wendy de Klerk, Wesley Huisman, Eva A. S. Koster, Arnoud H. de Ru, Peter van Balen, Sebastian Klobuch, Peter A. van Veelen, J. H. Frederik Falkenburg, Inge Jedema
Published 2022-02-01

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy

by Charlotte M. Mousset, Willemijn Hobo, Yun Ji, Hanny Fredrix, Valeria De Giorgi, Robert D. Allison, Michel G. D. Kester, J. H. Frederik Falkenburg, Nicolaas P. M. Schaap, Joop H. Jansen, Luca Gattinoni, Harry Dolstra, Anniek B. van der Waart
Published 2018-10-01

Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

by Maarten L. Zandvliet, J.H. Frederik Falkenburg, Ellis van Liempt, Louise A. Veltrop-Duits, Arjan C. Lankester, Jayant S. Kalpoe, Michel G.D. Kester, Dirk M. van der Steen, Maarten J. van Tol, Roel Willemze, Henk-Jan Guchelaar, Marco W. Schilham, Pauline Meij
Published 2010-11-01

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

by Margot J. Pont, Willemijn Hobo, Maria W. Honders, Simone A.P. van Luxemburg-Heijs, Michel G.D. Kester, Annemarie M. van Oeveren-Rietdijk, Nicolaas Schaap, Hetty C. de Boer, Cornelis A.M. van Bergen, Harry Dolstra, J.H. Frederik Falkenburg, Marieke Griffioen
Published 2015-10-01

Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.

by Wendy W J Unger, Todd Pearson, Joana R F Abreu, Sandra Laban, Arno R van der Slik, Sacha Mulder-van der Kracht, Michel G D Kester, Dave V Serreze, Leonard D Shultz, Marieke Griffioen, Jan Wouter Drijfhout, Dale L Greiner, Bart O Roep
Published 2012-01-01

WT1-specific TCRs directed against newly identified peptides install antitumor reactivity against acute myeloid leukemia and ovarian carcinoma

by Peter A van Veelen, Marieke Griffioen, Arnoud H de Ru, Anne K Wouters, Dennis F G Remst, J H Frederik Falkenburg, Mirjam H M Heemskerk, Rosa A van Amerongen, Renate S Hagedoorn, Danique C Assendelft, Dirk M van der Steen, Marian van de Meent, Michel G D Kester
Published 2022-06-01

Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain

by Miranda H. Meeuwsen, Anne K. Wouters, Tassilo L. A. Wachsmann, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud H. de Ru, Els P. van Hees, Martijn Kremer, Marieke Griffioen, Peter A. van Veelen, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk
Published 2023-02-01

A library of cancer testis specific T cell receptors for T cell receptor gene therapy

by Marije A.J. de Rooij, Dennis F.G. Remst, Dirk M. van der Steen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, Miranda H. Meeuwsen, Tassilo L.A. Wachsmann, Arnoud H. de Ru, Peter A. van Veelen, Els M.E. Verdegaal, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Published 2023-12-01

A library of cancer testis specific T cell receptors for T cell receptor gene therapy

by Marije A.J. de Rooij, Dennis F.G. Remst, Dirk M. van der Steen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, Miranda H. Meeuwsen, Tassilo L.A. Wachsmann, Arnoud H. de Ru, Peter A. van Veelen, Els M.E. Verdegaal, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Published 2023-03-01

An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML

by Dyantha I. van der Lee, Georgia Koutsoumpli, Rogier M. Reijmers, M. Willy Honders, Rob C. M. de Jong, Dennis F. G. Remst, Tassilo L. A. Wachsmann, Renate S. Hagedoorn, Kees L. M. C. Franken, Michel G. D. Kester, Karl J. Harber, Lisanne M. Roelofsen, Annemiek M. Schouten, Arend Mulder, Jan W. Drijfhout, Hendrik Veelken, Peter A. van Veelen, Mirjam H. M. Heemskerk, J.H. Frederik Falkenburg, Marieke Griffioen
Published 2021-10-01