Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases

by Ashley J. Canning, Susan Viggiano, Martin E. Fernandez-Zapico, Michael S. Cosgrove
Published 2022-11-01

Disentangling the recognition complexity of a protein hub using a nanopore

by Lauren Ashley Mayse, Ali Imran, Motahareh Ghahari Larimi, Michael S. Cosgrove, Aaron James Wolfe, Liviu Movileanu
Published 2022-02-01

Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism

by Kevin E. W. Namitz, Tongyin Zheng, Ashley J. Canning, Nilda L. Alicea-Velazquez, Carlos A. Castañeda, Michael S. Cosgrove, Steven D. Hanes
Published 2021-03-01

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1

by Lili Liao, Nilda L. Alicea‐Velázquez, Lauren Langbein, Xiaohua Niu, Weijia Cai, Eun‐Ah Cho, Meiling Zhang, Celeste B. Greer, Qin Yan, Michael S. Cosgrove, Haifeng Yang
Published 2019-04-01

EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction

by Jing Zhao, Alan Blayney, Xiaorong Liu, Lauren Gandy, Weihua Jin, Lufeng Yan, Jeung-Hoi Ha, Ashley J. Canning, Michael Connelly, Chao Yang, Xinyue Liu, Yuanyuan Xiao, Michael S. Cosgrove, Sozanne R. Solmaz, Yingkai Zhang, David Ban, Jianhan Chen, Stewart N. Loh, Chunyu Wang
Published 2021-02-01

An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

by Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas L Young, Michael-Christopher Keogh, Brian D Strahl
Published 2023-05-01

Data publication with the structural biology data grid supports live analysis

by Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Published 2016-03-01

Toward clinical genomics in everyday medicine: perspectives and recommendations

by Delaney, Susan K., Hultner, Michael L., Jacob, Howard J., Ledbetter, David H., McCarthy, Jeanette J., Ball, Michael, Beckman, Kenneth B., Belmont, John W., Bloss, Cinnamon S., Christman, Michael F., Cosgrove, Andy, Damiani, Stephen A., Danis, Timothy, Delledonne, Massimo, Dougherty, Michael J., Dudley, Joel T., Faucett, W. Andrew, Friedman, Jennifer R., Haase, David H., Hays, Tom S., Heilsberg, Stu, Huber, Jeff, Kaminsky, Leah, Ledbetter, Nikki, Lee, Warren H., Levin, Elissa, Libiger, Ondrej, Linderman, Michael, Love, Richard L., Magnus, David C., Martland, AnneMarie, McClure, Susan L., Megill, Scott E., Messier, Helen, Nussbaum, Robert L., Palaniappan, Latha, Patay, Bradley A., Popovich, Bradley W., Quackenbush, John, Savant, Mark J., Su, Michael M., Terry, Sharon F., Tucker, Steven, Wong, William T., Green, Robert C.
Published 2016