mTORC1 Controls Synthesis of Its Activator GTP

by Don Benjamin, Michael N. Hall
Published 2017-06-01

Regulation of mTORC2 Signaling

by Wenxiang Fu, Michael N. Hall
Published 2020-09-01

Combining metformin with lactate transport inhibitors as a treatment modality for cancer - recommendation proposal

by Don Benjamin, Michael N. Hall
Published 2022-10-01

mTORC2 regulates auditory hair cell structure and function

by Maurizio Cortada, Soledad Levano, Michael N. Hall, Daniel Bodmer
Published 2023-09-01

Colitis Is Associated with Loss of the Histidine Phosphatase LHPP and Upregulation of Histidine Phosphorylation in Intestinal Epithelial Cells

by Markus Linder, Dritan Liko, Venkatesh Kancherla, Salvatore Piscuoglio, Michael N. Hall
Published 2023-08-01

Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis

by Irina C. Frei, Diana Weissenberger, Danilo Ritz, Wolf Heusermann, Marco Colombi, Mitsugu Shimobayashi, Michael N. Hall
Published 2022-11-01

TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiae.

by Asier González, Mitsugu Shimobayashi, Tobias Eisenberg, David Adrian Merle, Tobias Pendl, Michael N Hall, Tarek Moustafa
Published 2015-01-01

A reference map of sphingolipids in murine tissues

by Sneha Muralidharan, Mitsugu Shimobayashi, Shanshan Ji, Bo Burla, Michael N. Hall, Markus R. Wenk, Federico Torta
Published 2021-06-01

Regulation of human mTOR complexes by DEPTOR

by Matthias Wälchli, Karolin Berneiser, Francesca Mangia, Stefan Imseng, Louise-Marie Craigie, Edward Stuttfeld, Michael N Hall, Timm Maier
Published 2021-09-01

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

by Xiaolei Ding, Wilhelm Bloch, Sandra Iden, Markus A. Rüegg, Michael N. Hall, Maria Leptin, Linda Partridge, Sabine A. Eming
Published 2016-10-01

PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.

by Kathrin Thedieck, Pazit Polak, Man Lyang Kim, Klaus D Molle, Adiel Cohen, Paul Jenö, Cécile Arrieumerlou, Michael N Hall
Published 2007-01-01

Architecture of the human mTORC2 core complex

by Edward Stuttfeld, Christopher HS Aylett, Stefan Imseng, Daniel Boehringer, Alain Scaiola, Evelyn Sauer, Michael N Hall, Timm Maier, Nenad Ban
Published 2018-02-01

Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model.

by Polina Suter, Eva Dazert, Jack Kuipers, Charlotte K Y Ng, Tuyana Boldanova, Michael N Hall, Markus H Heim, Niko Beerenwinkel
Published 2022-09-01

WNT7B promotes bone formation in part through mTORC1.

by Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M Arbeit, Markus A Rüegg, Michael N Hall, Liang Ma, Fanxin Long
Published 2014-01-01

Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice

by Manuel Blandino-Rosano, Ruy Andrade Louzada, Joao Pedro Werneck-De-Castro, Camila Lubaczeuski, Joana Almaça, Markus A. Rüegg, Michael N. Hall, Gil Leibowitz, Ernesto Bernal-Mizrachi
Published 2023-09-01

Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells

by Don Benjamin, Dimitri Robay, Sravanth K. Hindupur, Jens Pohlmann, Marco Colombi, Mahmoud Y. El-Shemerly, Sauveur-Michel Maira, Christoph Moroni, Heidi A. Lane, Michael N. Hall
Published 2018-12-01

A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice

by Fei Tang, Peng Zhang, Peiying Ye, Christopher A Lazarski, Qi Wu, Ingrid L Bergin, Timothy P Bender, Michael N Hall, Ya Cui, Liguo Zhang, Taijiao Jiang, Yang Liu, Pan Zheng
Published 2017-12-01

Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing

by Manuel Blandino-Rosano, Rebecca Barbaresso, Margarita Jimenez-Palomares, Nadejda Bozadjieva, Joao Pedro Werneck-de-Castro, Masayuki Hatanaka, Raghavendra G. Mirmira, Nahum Sonenberg, Ming Liu, Markus A. Rüegg, Michael N. Hall, Ernesto Bernal-Mizrachi
Published 2017-07-01

Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner

by Lianjun Zhang, Benjamin O. Tschumi, Isabel C. Lopez-Mejia, Susanne G. Oberle, Marten Meyer, Guerric Samson, Markus A. Rüegg, Michael N. Hall, Lluis Fajas, Dietmar Zehn, Jean-Pierre Mach, Alena Donda, Pedro Romero
Published 2016-02-01

KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae

by Eduardo I. Kessi-Pérez, Eduardo I. Kessi-Pérez, Francisco Salinas, Francisco Salinas, Francisco Salinas, Asier González, Ying Su, José M. Guillamón, Michael N. Hall, Luis F. Larrondo, Luis F. Larrondo, Claudio Martínez, Claudio Martínez
Published 2019-07-01