Newborn Screening for Lysosomal Storage Diseases: Methodologies, Screen Positive Rates, Normalization of Datasets, Second-Tier Tests, and Post-Analysis Tools

by Michael H. Gelb
Published 2018-07-01

The Importance of Assay Imprecision near the Screen Cutoff for Newborn Screening of Lysosomal Storage Diseases

by Bruce H. Robinson, Michael H. Gelb
Published 2019-03-01

Stratification of patients with lysosomal acid lipase deficiency by enzyme activity in dried blood spots

by Xinying Hong, Yicheng Chen, Marianne Barr, Michael H. Gelb
Published 2022-12-01

Improved method for the quantification of lysophospholipids including enol ether species by liquid chromatography-tandem mass spectrometry[S]

by James G. Bollinger, Hiromi Ii, Martin Sadilek, Michael H. Gelb
Published 2010-02-01

LC/ESI-MS/MS detection of FAs by charge reversal derivatization with more than four orders of magnitude improvement in sensitivity[S]

by James G. Bollinger, Gajendra Rohan, Martin Sadilek, Michael H. Gelb
Published 2013-12-01

Comparison of tandem mass spectrometry to fluorimetry for newborn screening of LSDs

by Michael H. Gelb, C. Ronald Scott, Frantisek Turecek, Hsuan-Chieh Liao
Published 2017-09-01

Multiplex tandem mass spectrometry enzymatic activity assay for the screening and diagnosis of Mucolipidosis type II and III

by Xinying Hong, Laura Pollard, Miao He, Michael H. Gelb, Timothy C. Wood
Published 2023-06-01

Newborn Screening for Lysosomal Storage Disorders: Methodologies for Measurement of Enzymatic Activities in Dried Blood Spots

by Michael H. Gelb, Zoltan Lukacs, Enzo Ranieri, Peter C. J. I. Schielen
Published 2018-12-01

Assay of phospholipases A2 and their inhibitors by kinetic analysis in the scooting mode

by Mahendra Kumar Jain, Bao-Zhu Yu, Michael H. Gelb, Otto G. Berg
Published 1992-01-01

Evaluation of Multiple Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis-I

by Zackary M. Herbst, Leslie Urdaneta, Terri Klein, Maria Fuller, Michael H. Gelb
Published 2020-08-01

Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation

by Richard T. Eastman, Frederick S. Buckner, Kohei Yokoyama, Michael H. Gelb, Wesley C. Van Voorhis
Published 2006-02-01

Family Attitudes regarding Newborn Screening for Krabbe Disease: Results from a Survey of Leukodystrophy Registries

by Karlita Blackwell, Michael H. Gelb, Anna Grantham, Natasha Spencer, Christin Webb, Tara West
Published 2020-08-01

Study of the role of cytosolic phospholipase A2 alpha in eicosanoid generation and thymocyte maturation in the thymus.

by Matthieu Rousseau, Gajendra S Naika, Jean Perron, Frederic Jacques, Michael H Gelb, Eric Boilard
Published 2015-01-01

First-tier next-generation sequencing for newborn screening: An important role for biochemical second-tier testing

by Sarah L. Stenton, Madelynn Campagna, Anthony Philippakis, Anne O'Donnell-Luria, Michael H. Gelb
Published 2023-01-01

Group IVC cytosolic phospholipase A2γ is farnesylated and palmitoylated in mammalian cells

by Dawn E. Tucker, Allison Stewart, Laxman Nallan, Pravine Bendale, Farideh Ghomashchi, Michael H. Gelb, Christina C. Leslie
Published 2005-10-01

Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach

by Frederick S. Buckner, Andriy Buchynskyy, Pendem Nagendar, Donald A. Patrick, J. Robert Gillespie, Zackary Herbst, Richard R. Tidwell, Michael H. Gelb
Published 2020-02-01

Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II

by Zackary M. Herbst, Leslie Urdaneta, Terri Klein, Barbara K. Burton, Khaja Basheeruddin, Hsuan-Chieh Liao, Maria Fuller, Michael H. Gelb
Published 2022-01-01

Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration.

by Conlan Kreher, Jacob Favret, Nadav I Weinstock, Malabika Maulik, Xinying Hong, Michael H Gelb, Lawrence Wrabetz, M Laura Feltri, Daesung Shin
Published 2022-07-01

Key role of group v secreted phospholipase A2 in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.

by William R Henderson, Xin Ye, Ying Lai, Zhanglin Ni, James G Bollinger, Ying-Tzang Tien, Emil Y Chi, Michael H Gelb
Published 2013-01-01

Bioactivity of Farnesyltransferase Inhibitors Against Entamoeba histolytica and Schistosoma mansoni

by Alexandra Probst, Thi N. Nguyen, Nelly El-Sakkary, Danielle Skinner, Brian M. Suzuki, Frederick S. Buckner, Michael H. Gelb, Conor R. Caffrey, Anjan Debnath
Published 2019-05-01