A pan-cancer fingerprint: common molecular denominators of the human tumor microenvironment

by Susanna S. Ng, Sonia Leonardelli, Michael Hölzel
Published 2021-11-01

From Tpex to Tex: a journey through CD8+ T cell responses in cancer immunotherapy

by Julia M. Messmer, Maike Effern, Michael Hölzel
Published 2023-09-01

Abscopal Effects in Metastatic Cancer: Is a Predictive Approach Possible to Improve Individual Outcomes?

by Barbara Link, Adriana Torres Crigna, Michael Hölzel, Frank A. Giordano, Olga Golubnitschaja
Published 2021-10-01

Pretreatment albumin is a prognostic and predictive biomarker for response to atezolizumab across solid tumors

by Jonas Saal, Jörg Ellinger, Manuel Ritter, Peter Brossart, Michael Hölzel, Niklas Klümper, Tobias Bald
Published 2023-01-01

Downstream neighbor of SON (DONSON) is associated with unfavorable survival across diverse cancers with oncogenic properties in clear cell renal cell carcinoma

by Niklas Klümper, Iulia Blajan, Doris Schmidt, Glen Kristiansen, Marieta Toma, Michael Hölzel, Manuel Ritter, Jörg Ellinger
Published 2020-11-01

CRISPitope: A generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models

by Maike Effern, Nicole Glodde, Emma Bawden, Jana Liebing, Daniel Hinze, Thomas Tüting, Thomas Gebhardt, Michael Hölzel
Published 2022-03-01

Low-Dose Acetylsalicylic Acid Treatment in Non-Skull-Base Meningiomas: Impact on Tumor Proliferation and Seizure Burden

by Johannes Wach, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Marieta Toma, Michael Hölzel, Erdem Güresir
Published 2022-09-01

Combining FORGE Score and Histopathological Diagnostic Criteria of Atypical Meningioma Enables Risk Stratification of Tumor Progression

by Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Albert J. Becker, Michael Hölzel, Marieta Toma, Erdem Güresir
Published 2021-10-01

Inflammatory Tumor Microenvironment in Cranial Meningiomas: Clinical Implications and Intraindividual Reproducibility

by Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Marieta Toma, Michael Hölzel, Erdem Güresir
Published 2022-03-01

Increased MIB-1 Labeling Index Is Associated with Abducens Nerve Morbidity in Primary Sporadic Petroclival Meningioma Surgery: Beyond Location and Approach

by Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Marieta Toma, Michael Hölzel, Erdem Güresir
Published 2022-07-01

The myeloid cell type I IFN system promotes antitumor immunity over pro‐tumoral inflammation in cancer T‐cell therapy

by Janne Ruotsalainen, Dorys Lopez‐Ramos, Meri Rogava, Naveen Shridhar, Nicole Glodde, Evelyn Gaffal, Michael Hölzel, Tobias Bald, Thomas Tüting
Published 2021-01-01

FORGE: A Novel Scoring System to Predict the MIB-1 Labeling Index in Intracranial Meningiomas

by Johannes Wach, Tim Lampmann, Ági Güresir, Patrick Schuss, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Michael Hölzel, Marieta Toma, Erdem Güresir
Published 2021-07-01

The CD73 is induced by TGF-β1 triggered by nutrient deprivation and highly expressed in dedifferentiated human melanoma

by Caterina Giraulo, Roberta Turiello, Lavinia Orlando, Sonia Leonardelli, Jennifer Landsberg, Raffaella Belvedere, Georg Rolshoven, Christa E. Müller, Michael Hölzel, Silvana Morello
Published 2023-09-01

Proliferative Potential, and Inflammatory Tumor Microenvironment in Meningioma Correlate with Neurological Function at Presentation and Anatomical Location—From Convexity to Skull...

by Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Silvia Cases-Cunillera, Michael Hölzel, Marieta Toma, Erdem Güresir
Published 2022-02-01

Downstream Neighbor of SON (DONSON) Expression Is Enhanced in Phenotypically Aggressive Prostate Cancers

by Niklas Klümper, Marthe von Danwitz, Johannes Stein, Doris Schmidt, Anja Schmidt, Glen Kristiansen, Michael Muders, Michael Hölzel, Manuel Ritter, Abdullah Alajati, Jörg Ellinger
Published 2020-11-01

Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma

by Michael Hölzel, Johanna A Seier, Julia Reinhardt, Kritika Saraf, Susanna S Ng, Julian P Layer, Dillon Corvino, Kristina Althoff, Frank A Giordano, Alexander Schramm, Matthias Fischer
Published 2021-05-01

CD103+ Tissue Resident T-Lymphocytes Accumulate in Lung Metastases and Are Correlated with Poor Prognosis in ccRCC

by Christine Sanders, Almotasem Salah M. Hamad, Susanna Ng, Racha Hosni, Jörg Ellinger, Niklas Klümper, Manuel Ritter, Carsten Stephan, Klaus Jung, Michael Hölzel, Glen Kristiansen, Stefan Hauser, Marieta I. Toma
Published 2022-03-01

C‐reactive protein flare‐response predicts long‐term efficacy to first‐line anti‐PD‐1‐based combination therapy in metastatic renal cell carcinoma

by Niklas Klümper, Philipp Schmucker, Oliver Hahn, Benedikt Höh, Angelika Mattigk, Severine Banek, Jörg Ellinger, Julia Heinzelbecker, Danijel Sikic, Markus Eckstein, Arne Strauß, Friedemann Zengerling, Michael Hölzel, Philip Zeuschner, Charis Kalogirou
Published 2021-01-01

Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy

by Laura K. Esser, Vittorio Branchi, Sonia Leonardelli, Natalie Pelusi, Adrian G. Simon, Niklas Klümper, Jörg Ellinger, Stefan Hauser, Maria A. Gonzalez-Carmona, Manuel Ritter, Glen Kristiansen, Hubert Schorle, Michael Hölzel, Marieta I. Toma
Published 2020-09-01

C reactive protein flare predicts response to checkpoint inhibitor treatment in non-small cell lung cancer

by Stefan Diem, Markus Joerger, Fiamma Berner, Lukas Flatz, Niklas Klümper, Manuel Ritter, Michael Hölzel, Jörg Ellinger, Peter Brossart, Annkristin Heine, Jonas Saal, Christa Lichtensteiger, Nina Wyss, Franz Georg Bauernfeind, Sabine Schmid, Martin Frueh, Tobias Bald
Published 2022-03-01