Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform

by Alexandra Colón-Rodríguez, José M. Uribe-Salazar, José M. Uribe-Salazar, KaeChandra B. Weyenberg, Aditya Sriram, Alejandra Quezada, Alejandra Quezada, Gulhan Kaya, Emily Jao, Brittany Radke, Pamela J. Lein, Pamela J. Lein, Megan Y. Dennis, Megan Y. Dennis, Megan Y. Dennis
Published 2020-11-01

Evaluation of CRISPR gene-editing tools in zebrafish

by José M. Uribe-Salazar, Gulhan Kaya, Aadithya Sekar, KaeChandra Weyenberg, Cole Ingamells, Megan Y. Dennis
Published 2022-01-01

Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing

by Daniela C. Soto, Colin Shew, Mira Mastoras, Joshua M. Schmidt, Ruta Sahasrabudhe, Gulhan Kaya, Aida M. Andrés, Megan Y. Dennis
Published 2020-03-01

Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4).

by Felix M Key, Benjamin Peter, Megan Y Dennis, Emilia Huerta-Sánchez, Wei Tang, Ludmila Prokunina-Olsson, Rasmus Nielsen, Aida M Andrés
Published 2014-10-01

Human local adaptation of the TRPM8 cold receptor along a latitudinal cline.

by Felix M Key, Muslihudeen A Abdul-Aziz, Roger Mundry, Benjamin M Peter, Aarthi Sekar, Mauro D'Amato, Megan Y Dennis, Joshua M Schmidt, Aida M Andrés
Published 2018-05-01

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

by Megan Y Dennis, Silvia Paracchini, Thomas S Scerri, Ludmila Prokunina-Olsson, Julian C Knight, Richard Wade-Martins, Penny Coggill, Stephan Beck, Eric D Green, Anthony P Monaco
Published 2009-03-01

FixItFelix: improving genomic analysis by fixing reference errors

by Sairam Behera, Jonathon LeFaive, Peter Orchard, Medhat Mahmoud, Luis F. Paulin, Jesse Farek, Daniela C. Soto, Stephen C. J. Parker, Albert V. Smith, Megan Y. Dennis, Justin M. Zook, Fritz J. Sedlazeck
Published 2023-02-01

Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

by Aida M Andrés, Megan Y Dennis, Warren W Kretzschmar, Jennifer L Cannons, Shih-Queen Lee-Lin, Belen Hurle, NISC Comparative Sequencing Program, Pamela L Schwartzberg, Scott H Williamson, Carlos D Bustamante, Rasmus Nielsen, Andrew G Clark, Eric D Green
Published 2010-10-01

A rare myelin protein zero (MPZ) variant alters enhancer activity in vitro and in vivo.

by Anthony Antonellis, Megan Y Dennis, Grzegorz Burzynski, Jimmy Huynh, Valerie Maduro, Chani J Hodonsky, Mehrdad Khajavi, Kinga Szigeti, Sandeep Mukkamala, Seneca L Bessling, William J Pavan, Andrew S McCallion, James R Lupski, Eric D Green, NISC Comparative Sequencing Program
Published 2010-12-01

Psychedelics Promote Structural and Functional Neural Plasticity

by Calvin Ly, Alexandra C. Greb, Lindsay P. Cameron, Jonathan M. Wong, Eden V. Barragan, Paige C. Wilson, Kyle F. Burbach, Sina Soltanzadeh Zarandi, Alexander Sood, Michael R. Paddy, Whitney C. Duim, Megan Y. Dennis, A. Kimberley McAllister, Kassandra M. Ori-McKenney, John A. Gray, David E. Olson
Published 2018-06-01

Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism

by Yihui Zhu, J. Antonio Gomez, Benjamin I. Laufer, Charles E. Mordaunt, Julia S. Mouat, Daniela C. Soto, Megan Y. Dennis, Kelly S. Benke, Kelly M. Bakulski, John Dou, Ria Marathe, Julia M. Jianu, Logan A. Williams, Orangel J. Gutierrez Fugón, Cheryl K. Walker, Sally Ozonoff, Jason Daniels, Luke P. Grosvenor, Heather E. Volk, Jason I. Feinberg, M. Daniele Fallin, Irva Hertz-Picciotto, Rebecca J. Schmidt, Dag H. Yasui, Janine M. LaSalle
Published 2022-02-01