P1485: PKM AND PKR EXPRESSION DURING HEMATOPOIESIS AND ERYTHROPOIESIS

by Erin Tsai, Leonardo Rivadeneyra, Saliha Yilmaz, Lenny Dang, Megan Wind-Rotolo
Published 2023-08-01

Development of a prognostic composite cytokine signature based on the correlation with nivolumab clearance: translational PK/PD analysis in patients with renal cell carcinoma

by Rui Wang, Junying Zheng, Xiao Shao, Yuko Ishii, Amit Roy, Akintunde Bello, Richard Lee, Joshua Zhang, Megan Wind-Rotolo, Yan Feng
Published 2019-12-01

PB1990: GLYCOLYTIC ACTIVITY AND EFFECT OF EX-VIVO TREATMENT WITH THE PYRUVATE KINASE (PK) ACTIVATOR AG-946 IN RED BLOOD CELLS FROM LOW-RISK MYELODYSPLASTIC SYNDROMES PATIENTS: A PR...

by Bruno Fattizzo, Cristina Vercellati, Anna Marcello, Parija Patel, Megan Wind-Rotolo, Loredana Pettine, Simona Leoni, Elisa Fermo, Paola Bianchi, Anna Zaninoni, Wilma Barcellini
Published 2023-08-01

P717: AG946, A PYRUVATE KINASE (PK) ACTIVATOR IMPROVES PK PROPERTIES AND RED BLOOD CELL (RBC) METABOLISM UPON EX VIVO TREATMENT OF RBCS FROM PATIENTS WITH MYELODYSPLASTIC SYNDROMES

by Jonathan de Wilde, Titine Ruiter, Brigitte van Oirschot, Judith Jans, Lenny Dang, Megan Wind-Rotolo, Wouter van Solinge, Anna van Rhenen, Richard Van Wijk, Minke Rab
Published 2023-08-01

Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC

by Mario Sznol, Toni K Choueiri, Scott D Chasalow, Petra Ross-MacDonald, Simon Papillon-Cavanagh, Alice M Walsh, Megan Wind-Rotolo, Ron Ammar, Peter M Szabo
Published 2021-03-01

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.

by Matthew A Burchill, Justin A Roby, Nanette Crochet, Megan Wind-Rotolo, Amy E Stone, Michael G Edwards, Rachael J Dran, Michael S Kriss, Michael Gale, Hugo R Rosen
Published 2017-01-01

387 The utility of AI-powered spatial classification of intratumoral CD8+ immune-cell distribution in predicting overall survival in patients with melanoma as part of the checkMate...

by Daniel Cohen, Akshita Gupta, Jimena Trillo-Tinoco, Hao Tang, Megan Wind-Rotolo, Benjamin Chen, Robin Edwards, George Lee, Keyur Desai, Scott Ely, John Wojcik, Daniel Tenney, Vipul Baxi
Published 2021-11-01

Soluble PD-L1 as an early marker of progressive disease on nivolumab

by David F McDermott, Gordon J Freeman, Toni K Choueiri, Petra Ross-MacDonald, F Stephen Hodi, Megan Wind-Rotolo, Long Yuan, Kathleen M Mahoney, Linan Song, Eliseo Veras
Published 2022-02-01

P1497: MITAPIVAT IMPROVES IRON OVERLOAD IN PATIENTS WITH PYRUVATE KINASE DEFICIENCY WHO ARE REGULARLY TRANSFUSED

by Eduard van Beers, Hanny Al-Samkari, Rachael F. Grace, Wilma Barcellini, Andreas Glenthøj, Vanessa Beynon, Megan Wind-Rotolo, Rengyi Xu, Melissa Dibacco, Parija Patel, John B. Porter, Kevin H.M. Kuo
Published 2023-08-01

Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma

by Jin Yao, Thomas Powles, David F McDermott, Toni K Choueiri, Petra Ross-MacDonald, Simon Papillon-Cavanagh, Robert J Motzer, M Brent McHenry, Megan Wind-Rotolo, Ron Ammar, Yann-Alexandre Vano, Saurabh Gupta, Celine Han, Shruti S Saggi
Published 2022-03-01

A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus...

by David Gardiner, Jay Lalezari, Eric Lawitz, Michael DiMicco, Rheem Ghalib, K Rajender Reddy, Kyong-Mi Chang, Mark Sulkowski, Steven O' Marro, Jeffrey Anderson, Bing He, Vikram Kansra, Fiona McPhee, Megan Wind-Rotolo, Dennis Grasela, Mark Selby, Alan J Korman, Israel Lowy
Published 2013-01-01

Metabolomic adaptations and correlates of survival to immune checkpoint blockade

by Haoxin Li, Kevin Bullock, Carino Gurjao, David Braun, Sachet A. Shukla, Dominick Bossé, Aly-Khan A. Lalani, Shuba Gopal, Chelsea Jin, Christine Horak, Megan Wind-Rotolo, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Eliezer M. Van Allen, Stuart L. Schreiber, F. Stephen Hodi, William R. Sellers, Levi A. Garraway, Clary B. Clish, Toni K. Choueiri, Marios Giannakis
Published 2019-09-01

Peg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients

by Sandra Phillips, Sandra Phillips, Sameer Mistry, Sameer Mistry, Antonio Riva, Antonio Riva, Helen Cooksley, Helen Cooksley, Tanya Hadzhiolova-Lebeau, Slava Plavova, Krum Katzarov, Marieta Simonova, Stephan Zeuzem, Clive Woffendin, Pei-Jer Chen, Cheng-Yuan Peng, Ting-Tsung Chang, Stefan Lueth, Robert De Knegt, Moon-Seok Choi, Heiner Wedemeyer, Michael Dao, Chang-Wook Kim, Heng-Chen Chu, Megan Wind-Rotolo, Roger Williams, Roger Williams, Elizabeth Cooney, Shilpa Chokshi, Shilpa Chokshi
Published 2017-05-01

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

by Ziad Bakouny, David A. Braun, Sachet A. Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie Vokes, Jackson Nyman, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A. Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant’Angelo, Juliet Forman, Jacob E. Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C. Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L. Chang, Xiao X. Wei, Bradley A. McGregor, Lauren C. Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S. Hirsch, Matthew L. Freedman, Michael B. Atkins, Catherine J. Wu, Thai H. Ho, W. Marston Linehan, David F. McDermott, Daniel Y. C. Heng, Srinivas R. Viswanathan, Sabina Signoretti, Eliezer M. Van Allen, Toni K. Choueiri
Published 2021-02-01