Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals

by Yoshihisa Uenoyama, Hitomi Tsuchida, Mayuko Nagae, Naoko Inoue, Hiroko Tsukamura
Published 2022-08-01

Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction

by Yoshihisa Uenoyama, Mayuko Nagae, Hitomi Tsuchida, Naoko Inoue, Hiroko Tsukamura
Published 2021-09-01

Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late...

by Arisa SUGIMOTO, Hitomi TSUCHIDA, Mayuko NAGAE, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA
Published 2022-03-01

Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats

by Sutisa MAJARUNE, Pelden Nima, Arisa SUGIMOTO, Mayuko NAGAE, Naoko INOUE, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Published 2019-05-01

Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats

by Koki YAMADA, Mayuko NAGAE, Tetsuya MANO, Hitomi TSUCHIDA, Safiullah HAZIM, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA
Published 2023-07-01

Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats

by Mayuko Nagae, Koki Yamada, Yuki Enomoto, Mari Kometani, Hitomi Tsuchida, Arvinda Panthee, Miku Nonogaki, Nao Matsunaga, Marina Takizawa, Sena Matsuzaki, Masumi Hirabayashi, Naoko Inoue, Hiroko Tsukamura, Yoshihisa Uenoyama
Published 2023-11-01

Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice

by Kana IKEGAMI, Teppei GOTO, Sho NAKAMURA, Youki WATANABE, Arisa SUGIMOTO, Sutisa MAJARUNE, Kei HORIHATA, Mayuko NAGAE, Junko TOMIKAWA, Takuya IMAMURA, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Kei-ichiro MAEDA, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Published 2020-04-01