Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort.

by Chris Lauber, Mathias J Gerl, Christian Klose, Filip Ottosson, Olle Melander, Kai Simons
Published 2022-03-01

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort

by Chris Lauber, Mathias J. Gerl, Christian Klose, Filip Ottosson, Olle Melander, Kai Simons
Published 2022-03-01

Flexibility of a eukaryotic lipidome--insights from yeast lipidomics.

by Christian Klose, Michal A Surma, Mathias J Gerl, Felix Meyenhofer, Andrej Shevchenko, Kai Simons
Published 2012-01-01

Mouse lipidomics reveals inherent flexibility of a mammalian lipidome

by Michał A. Surma, Mathias J. Gerl, Ronny Herzog, Jussi Helppi, Kai Simons, Christian Klose
Published 2021-09-01

A set of gene knockouts as a resource for global lipidomic changes

by Aleksandra Spiegel, Chris Lauber, Mandy Bachmann, Anne-Kristin Heninger, Christian Klose, Kai Simons, Mihail Sarov, Mathias J. Gerl
Published 2022-06-01

Lipidomics in Major Depressive Disorder

by Andreas Walther, Carlo Vittorio Cannistraci, Carlo Vittorio Cannistraci, Kai Simons, Claudio Durán, Mathias J. Gerl, Susanne Wehrli, Clemens Kirschbaum
Published 2018-10-01

Lipidome‐ and Genome‐Wide Study to Understand Sex Differences in Circulatory Lipids

by Rubina Tabassum, Sanni Ruotsalainen, Linda Ottensmann, Mathias J. Gerl, Christian Klose, Taru Tukiainen, Matti Pirinen, Kai Simons, Elisabeth Widén, Samuli Ripatti
Published 2022-10-01

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

by Linda Ottensmann, Rubina Tabassum, Sanni E. Ruotsalainen, Mathias J. Gerl, Christian Klose, Elisabeth Widén, FinnGen, Kai Simons, Samuli Ripatti, Matti Pirinen
Published 2023-10-01

Morphology and Molecular Composition of Purified Bovine Viral Diarrhea Virus Envelope.

by Nathalie Callens, Britta Brügger, Pierre Bonnafous, Hervé Drobecq, Mathias J Gerl, Thomas Krey, Gleyder Roman-Sosa, Till Rümenapf, Olivier Lambert, Jean Dubuisson, Yves Rouillé
Published 2016-03-01

Machine learning of human plasma lipidomes for obesity estimation in a large population cohort.

by Mathias J Gerl, Christian Klose, Michal A Surma, Celine Fernandez, Olle Melander, Satu Männistö, Katja Borodulin, Aki S Havulinna, Veikko Salomaa, Elina Ikonen, Carlo V Cannistraci, Kai Simons
Published 2019-10-01

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

by Mathias J Gerl, Verena Bittl, Susanne Kirchner, Timo Sachsenheimer, Hanna L Brunner, Christian Lüchtenborg, Cagakan Özbalci, Hannah Wiedemann, Sabine Wegehingel, Walter Nickel, Per Haberkant, Carsten Schultz, Marcus Krüger, Britta Brügger
Published 2016-01-01

Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population‐Ascertained Hyperlipidemias

by Joel T. Rämö, Pietari Ripatti, Rubina Tabassum, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Christian Klose, Michal A. Surma, Nathan O. Stitziel, Aki S. Havulinna, Matti Pirinen, Veikko Salomaa, Nelson B. Freimer, Matti Jauhiainen, Aarno Palotie, Marja‐Riitta Taskinen, Kai Simons, Samuli Ripatti
Published 2019-07-01

Shotgun mass spectrometry-based lipid profiling identifies and distinguishes between chronic inflammatory diseases

by Rune Matthiesen, Chris Lauber, Julio L. Sampaio, Neuza Domingues, Liliana Alves, Mathias J. Gerl, Manuel S. Almeida, Gustavo Rodrigues, Pedro Araújo Gonçalves, Jorge Ferreira, Cláudia Borbinha, João Pedro Marto, Marisa Neves, Frederico Batista, Miguel Viana-Baptista, Jose Alves, Kai Simons, Winchil L.C. Vaz, Otilia V. Vieira
Published 2021-08-01

Genetic architecture of human plasma lipidome and its link to cardiovascular disease

by Rubina Tabassum, Joel T. Rämö, Pietari Ripatti, Jukka T. Koskela, Mitja Kurki, Juha Karjalainen, Priit Palta, Shabbeer Hassan, Javier Nunez-Fontarnau, Tuomo T. J. Kiiskinen, Sanni Söderlund, Niina Matikainen, Mathias J. Gerl, Michal A. Surma, Christian Klose, Nathan O. Stitziel, Hannele Laivuori, Aki S. Havulinna, Susan K. Service, Veikko Salomaa, Matti Pirinen, FinnGen Project, Matti Jauhiainen, Mark J. Daly, Nelson B. Freimer, Aarno Palotie, Marja-Riitta Taskinen, Kai Simons, Samuli Ripatti
Published 2019-09-01

Multi-omics subgroups associated with glycaemic deterioration in type 2 diabetes: an IMI-RHAPSODY Study

by Shiying Li, Iulian Dragan, Van Du T. Tran, Chun Ho Fung, Dmitry Kuznetsov, Michael K. Hansen, Joline W. J. Beulens, Joline W. J. Beulens, Leen M. ‘t Hart, Leen M. ‘t Hart, Leen M. ‘t Hart, Leen M. ‘t Hart, Roderick C. Slieker, Louise A. Donnelly, Mathias J. Gerl, Christian Klose, Florence Mehl, Kai Simons, Petra J. M. Elders, Ewan R. Pearson, Guy A. Rutter, Guy A. Rutter, Guy A. Rutter, Mark Ibberson
Published 2024-03-01

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

by Roderick C. Slieker, Louise A. Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem, Ayşim Güneş, Frederic Abou Azar, Alexander Efanov, Eleni Georgiadou, Hermine Muniangi-Muhitu, Mahsa Sheikh, Giuseppe N. Giordano, Mikael Åkerlund, Emma Ahlqvist, Ashfaq Ali, Karina Banasik, Søren Brunak, Marko Barovic, Gerard A. Bouland, Frédéric Burdet, Mickaël Canouil, Iulian Dragan, Petra J. M. Elders, Celine Fernandez, Andreas Festa, Hugo Fitipaldi, Phillippe Froguel, Valborg Gudmundsdottir, Vilmundur Gudnason, Mathias J. Gerl, Amber A. van der Heijden, Lori L. Jennings, Michael K. Hansen, Min Kim, Isabelle Leclerc, Christian Klose, Dmitry Kuznetsov, Dina Mansour Aly, Florence Mehl, Diana Marek, Olle Melander, Anne Niknejad, Filip Ottosson, Imre Pavo, Kevin Duffin, Samreen K. Syed, Janice L. Shaw, Over Cabrera, Timothy J. Pullen, Kai Simons, Michele Solimena, Tommi Suvitaival, Asger Wretlind, Peter Rossing, Valeriya Lyssenko, Cristina Legido Quigley, Leif Groop, Bernard Thorens, Paul W. Franks, Gareth E. Lim, Jennifer Estall, Mark Ibberson, Joline W. J. Beulens, Leen M ’t Hart, Ewan R. Pearson, Guy A. Rutter
Published 2023-05-01

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

by Ejsing, Christer S., Surma, Michal A., Kaiser, Hermann-Josef, Gerl, Mathias J., Sampaio, Julio L., de Robillard, Quentin, Ferguson, Charles, Shevchenko, Andrej, Simons, Kai, Klemm, Robin, Proszynski, Tomasz Jacek
Published 2010