A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation

by Ryuichi Mashima, Mari Ohira, Torayuki Okuyama, Masafumi Onodera, Shuji Takada
Published 2023-05-01

Functional Domains of ZFP809 Essential for Nuclear Localization and Gene Silencing.

by Yu Ichida, Yuko Utsunomiya, Toru Yasuda, Kazuhiko Nakabayashi, Toshinori Sato, Masafumi Onodera
Published 2015-01-01

Foxo in T Cells Regulates Thermogenic Program through Ccr4/Ccl22 Axis

by Tetsuhiro Kikuchi, Jun Nakae, Yoshinaga Kawano, Nobuyuki Watanabe, Masafumi Onodera, Hiroshi Itoh
Published 2019-12-01

Safety and efficacy of elapegademase in patients with adenosine deaminase deficiency: A multicenter, open‐label, single‐arm, phase 3, and postmarketing clinical study

by Masafumi Onodera, Toru Uchiyama, Tadashi Ariga, Masafumi Yamada, Takako Miyamura, Hironori Arizono, Tomohiro Morio
Published 2023-07-01

An insulator element located at the cyclin B1 interacting protein 1 gene locus is highly conserved among mammalian species.

by Wataru Yoshida, Junko Tomikawa, Makoto Inaki, Hiroshi Kimura, Masafumi Onodera, Kenichiro Hata, Kazuhiko Nakabayashi
Published 2015-01-01

Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.

by Julia Tornack, Katharina Seiler, Andreas Grützkau, Joachim R Grün, Masafumi Onodera, Fritz Melchers, Motokazu Tsuneto
Published 2013-01-01

Enhanced osteoblastic differentiation of parietal bone in a novel murine model of mucopolysaccharidosis type II

by Narutoshi Yamazaki, Mari Ohira, Shuji Takada, Akira Ohtake, Masafumi Onodera, Mahito Nakanishi, Torayuki Okuyama, Ryuichi Mashima
Published 2023-12-01

Time-lapse imaging reveals symmetric neurogenic cell division of GFAP-expressing progenitors for expansion of postnatal dentate granule neurons.

by Takashi Namba, Hideki Mochizuki, Ryusuke Suzuki, Masafumi Onodera, Masahiro Yamaguchi, Hideo Namiki, Seiji Shioda, Tatsunori Seki
Published 2011-01-01

Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy

by Yuka Igarashi, Toru Uchiyama, Tomoko Minegishi, Sirirat Takahashi, Nobuyuki Watanabe, Toshinao Kawai, Masafumi Yamada, Tadashi Ariga, Masafumi Onodera
Published 2017-09-01

Ultracentrifugation-free chromatography-mediated large-scale purification of recombinant adeno-associated virus serotype 1 (rAAV1)

by Taro Tomono, Yukihiko Hirai, Hironori Okada, Kumi Adachi, Akiko Ishii, Takashi Shimada, Masafumi Onodera, Akira Tamaoka, Takashi Okada
Published 2016-01-01

Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells

by Hironari Nishizawa, Mitsuyo Matsumoto, Guan Chen, Yusho Ishii, Keisuke Tada, Masafumi Onodera, Hiroki Kato, Akihiko Muto, Kozo Tanaka, Kazuhiko Igarashi
Published 2021-03-01

Human Genomic Safe Harbors and the Suicide Gene‐Based Safeguard System for iPSC‐Based Cell Therapy

by Yasuyoshi Kimura, Tomoko Shofuda, Yuichiro Higuchi, Ippei Nagamori, Masaaki Oda, Masayuki Nakamori, Masafumi Onodera, Daisuke Kanematsu, Atsuyo Yamamoto, Asako Katsuma, Hiroshi Suemizu, Toru Nakano, Yonehiro Kanemura, Hideki Mochizuki
Published 2019-07-01

Highly Efficient Ultracentrifugation-free Chromatographic Purification of Recombinant AAV Serotype 9

by Taro Tomono, Yukihiko Hirai, Hironori Okada, Yoshitaka Miyagawa, Kumi Adachi, Shuhei Sakamoto, Yasuhiro Kawano, Hideto Chono, Junichi Mineno, Akiko Ishii, Takashi Shimada, Masafumi Onodera, Akira Tamaoka, Takashi Okada
Published 2018-12-01

Nonconditioned ADA-SCID gene therapy reveals ADA requirement in the hematopoietic system and clonal dominance of vector-marked clones

by Toru Uchiyama, Sirirat Takahashi, Kazuhiko Nakabayashi, Kohji Okamura, Kaori Edasawa, Masafumi Yamada, Nobuyuki Watanabe, Emi Mochizuki, Toru Yasuda, Akane Miura, Motohiro Kato, Daisuke Tomizawa, Makoto Otsu, Tadashi Ariga, Masafumi Onodera
Published 2021-12-01

Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells

by Yusuke Azami, Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Ken-ichi Kudo, Akinobu Ota, Karnan Sivasundaram, Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Shigehira Saji, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai
Published 2021-03-01

Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells

by Fumihiko Kawamura, Makoto Inaki, Atsushi Katafuchi, Yu Abe, Naohiro Tsuyama, Yumiko Kurosu, Aki Yanagi, Mitsunori Higuchi, Satoshi Muto, Takumi Yamaura, Hiroyuki Suzuki, Hideyoshi Noji, Shinichi Suzuki, Mitsuaki A. Yoshida, Megumi Sasatani, Kenji Kamiya, Masafumi Onodera, Akira Sakai
Published 2017-05-01

Haploinsufficiency of A20 caused by a novel nonsense variant or entire deletion of TNFAIP3 is clinically distinct from Behçet’s disease

by Naomi Tsuchida, Yohei Kirino, Yutaro Soejima, Masafumi Onodera, Katsuhiro Arai, Eiichiro Tamura, Takashi Ishikawa, Toshinao Kawai, Toru Uchiyama, Shigeru Nomura, Daisuke Kobayashi, Masataka Taguri, Satomi Mitsuhashi, Takeshi Mizuguchi, Atsushi Takata, Noriko Miyake, Hideaki Nakajima, Satoko Miyatake, Naomichi Matsumoto
Published 2019-06-01