Protein Complex Organization Imposes Constraints on Proteome Dysregulation in Cancer

by Gökçe Senger, Martin H. Schaefer
Published 2021-08-01

Cancer genomes tolerate deleterious coding mutations through somatic copy number amplifications of wild-type regions

by Fabio Alfieri, Giulio Caravagna, Martin H. Schaefer
Published 2023-06-01

Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors

by Gökçe Senger, Stefano Santaguida, Martin H Schaefer
Published 2022-05-01

A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference

by Dina Cramer, Luis Serrano, Martin H Schaefer
Published 2016-11-01

Author Correction: Cancer genomes tolerate deleterious coding mutations through somatic copy number amplifications of wild-type regions

by Fabio Alfieri, Giulio Caravagna, Martin H. Schaefer
Published 2023-07-01

Correcting for the study bias associated with protein-protein interaction measurements reveals differences between protein degree distributions from different cancer types

by Martin H Schaefer, Martin H Schaefer, Luis eSerrano, Luis eSerrano, Luis eSerrano, Miguel A Andrade-Navarro, Miguel A Andrade-Navarro
Published 2015-08-01

Translational efficiency across healthy and tumor tissues is proliferation‐related

by Xavier Hernandez‐Alias, Hannah Benisty, Martin H Schaefer, Luis Serrano
Published 2021-03-01

Translational efficiency across healthy and tumor tissues is proliferation‐related

by Xavier Hernandez‐Alias, Hannah Benisty, Martin H Schaefer, Luis Serrano
Published 2020-03-01

Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways.

by Martin H Schaefer, Jae-Seong Yang, Luis Serrano, Christina Kiel
Published 2014-06-01

Using protein-per-mRNA differences among human tissues in codon optimization

by Xavier Hernandez-Alias, Hannah Benisty, Leandro G. Radusky, Luis Serrano, Martin H. Schaefer
Published 2023-02-01

Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome

by Luis Zapata, Oriol Pich, Luis Serrano, Fyodor A. Kondrashov, Stephan Ossowski, Martin H. Schaefer
Published 2018-05-01

HIPPIE: Integrating protein interaction networks with experiment based quality scores.

by Martin H Schaefer, Jean-Fred Fontaine, Arunachalam Vinayagam, Pablo Porras, Erich E Wanker, Miguel A Andrade-Navarro
Published 2012-01-01

Functional and genomic analyses of alpha-solenoid proteins.

by David Fournier, Gareth A Palidwor, Sergey Shcherbinin, Angelika Szengel, Martin H Schaefer, Carol Perez-Iratxeta, Miguel A Andrade-Navarro
Published 2013-01-01

Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function

by Fabian Hosp, Sara Gutiérrez-Ángel, Martin H. Schaefer, Jürgen Cox, Felix Meissner, Mark S. Hipp, F.-Ulrich Hartl, Rüdiger Klein, Irina Dudanova, Matthias Mann
Published 2017-11-01

Silencing of SRRM4 suppresses microexon inclusion and promotes tumor growth across cancers.

by Sarah A Head, Xavier Hernandez-Alias, Jae-Seong Yang, Ludovica Ciampi, Violeta Beltran-Sastre, Antonio Torres-Méndez, Manuel Irimia, Martin H Schaefer, Luis Serrano
Published 2021-02-01

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.

by Martin H Schaefer, Tiago J S Lopes, Nancy Mah, Jason E Shoemaker, Yukiko Matsuoka, Jean-Fred Fontaine, Caroline Louis-Jeune, Amie J Eisfeld, Gabriele Neumann, Carol Perez-Iratxeta, Yoshihiro Kawaoka, Hiroaki Kitano, Miguel A Andrade-Navarro
Published 2013-01-01

Location and condition based reconstruction of colon cancer microbiome from human RNA sequencing data

by Gaia Sambruni, Angeli D. Macandog, Jakob Wirbel, Danilo Cagnina, Carlotta Catozzi, Tiziano Dallavilla, Francesca Borgo, Nicola Fazio, Uberto Fumagalli-Romario, Wanda L. Petz, Teresa Manzo, Simona P. Ravenda, Georg Zeller, Luigi Nezi, Martin H. Schaefer
Published 2023-05-01

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.

by Spyros Petrakis, Tamás Raskó, Jenny Russ, Ralf P Friedrich, Martin Stroedicke, Sean-Patrick Riechers, Katja Muehlenberg, Angeli Möller, Anita Reinhardt, Arunachalam Vinayagam, Martin H Schaefer, Michael Boutros, Hervé Tricoire, Miguel A Andrade-Navarro, Erich E Wanker
Published 2012-01-01

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

by Apichat Suratanee, Martin H Schaefer, Matthew J Betts, Zita Soons, Heiko Mannsperger, Nathalie Harder, Marcus Oswald, Markus Gipp, Ellen Ramminger, Guillermo Marcus, Reinhard Männer, Karl Rohr, Erich Wanker, Robert B Russell, Robert B Russell, Miguel A Andrade-Navarro, Roland Eils, Rainer König
Published 2014-09-01

Author Correction: GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

by Silvia Tiberti, Carlotta Catozzi, Ottavio Croci, Mattia Ballerini, Danilo Cagnina, Chiara Soriani, Caterina Scirgolea, Zheng Gong, Jiatai He, Angeli D. Macandog, Amir Nabinejad, Carina B. Nava Lauson, Arianna Quinte’, Giovanni Bertalot, Wanda L. Petz, Simona P. Ravenda, Valerio Licursi, Paola Paci, Marco Rasponi, Luca Rotta, Nicola Fazio, Guangwen Ren, Uberto Fumagalli-Romario, Martin H. Schaefer, Stefano Campaner, Enrico Lugli, Luigi Nezi, Teresa Manzo
Published 2022-11-01