Hepatocarcinoma Induces a Tumor Necrosis Factor-Dependent Kupffer Cell Death Pathway That Favors Its Proliferation Upon Partial Hepatectomy

by Jean-François Hastir, Sandrine Delbauve, Lionel Larbanoix, Desislava Germanova, Cleo Goyvaerts, Justine Allard, Sophie Laurent, Karine Breckpot, Alain Beschin, Alain Beschin, Martin Guilliams, Martin Guilliams, Véronique Flamand
Published 2020-10-01

Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling.

by Tom Bosschaerts, Martin Guilliams, Benoît Stijlemans, Yannick Morias, Daniel Engel, Frank Tacke, Michel Hérin, Patrick De Baetselier, Alain Beschin
Published 2010-08-01

Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into Macrophages.

by Yannick Morias, Chloé Abels, Damya Laoui, Eva Van Overmeire, Martin Guilliams, Elio Schouppe, Frank Tacke, Carlie J deVries, Patrick De Baetselier, Alain Beschin
Published 2015-05-01

Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions

by Miriam Wöhner, Sarah Brechtelsbauer, Niklas Friedrich, Christof Vorsatz, Johanna Bulang, Chunguang Liang, Lena Schorr, Alain Beschin, Martin Guilliams, Jeffrey Ravetch, Falk Nimmerjahn, Markus Biburger
Published 2024-02-01

COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

by Keren Cohen, Odelia Mouhadeb, Shani Ben Shlomo, Marva Langer, Anat Neumann, Noam Erez, Itay Moshkovits, Rotem Pelet, Daniel J. Kedar, Eli Brazowski, Martin Guilliams, Helen S. Goodridge, Nathan Gluck, Chen Varol
Published 2021-11-01

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

by Calum C. Bain, Catherine A. Hawley, Hannah Garner, Charlotte L. Scott, Anika Schridde, Nicholas J. Steers, Matthias Mack, Anagha Joshi, Martin Guilliams, Allan Mc I. Mowat, Frederic Geissmann, Stephen J. Jenkins
Published 2016-06-01

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

by Charlotte L. Scott, Fang Zheng, Patrick De Baetselier, Liesbet Martens, Yvan Saeys, Sofie De Prijck, Saskia Lippens, Chloé Abels, Steve Schoonooghe, Geert Raes, Nick Devoogdt, Bart N. Lambrecht, Alain Beschin, Martin Guilliams
Published 2016-01-01

Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function

by Helena M. Izquierdo, Paola Brandi, Manuel-José Gómez, Ruth Conde-Garrosa, Elena Priego, Michel Enamorado, Sarai Martínez-Cano, Iria Sánchez, Laura Conejero, Daniel Jimenez-Carretero, Silvia Martín-Puig, Martin Guilliams, David Sancho
Published 2018-08-01

Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

by Katrien Van der Borght, Charlotte L. Scott, Veronika Nindl, Ann Bouché, Liesbet Martens, Dorine Sichien, Justine Van Moorleghem, Manon Vanheerswynghels, Sofie De Prijck, Yvan Saeys, Burkhard Ludewig, Thierry Gillebert, Martin Guilliams, Peter Carmeliet, Bart N. Lambrecht
Published 2017-03-01

The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β.

by Anouk K Gloudemans, Maud Plantinga, Martin Guilliams, Monique A Willart, Arifa Ozir-Fazalalikhan, Alwin van der Ham, Louis Boon, Nicola L Harris, Hamida Hammad, Henk C Hoogsteden, Maria Yazdanbakhsh, Rudi W Hendriks, Bart N Lambrecht, Hermelijn H Smits
Published 2013-01-01

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

by Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter
Published 2016-12-01

Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens

by Sylvain Normand, Nadine Waldschmitt, Andreas Neerincx, Ruben Julio Martinez-Torres, Camille Chauvin, Aurélie Couturier-Maillard, Olivier Boulard, Laetitia Cobret, Fawaz Awad, Ludovic Huot, Andre Ribeiro-Ribeiro, Katja Lautz, Richard Ruez, Myriam Delacre, Clovis Bondu, Martin Guilliams, Charlotte Scott, Anthony Segal, Serge Amselem, David Hot, Sonia Karabina, Erwin Bohn, Bernhard Ryffel, Lionel F. Poulin, Thomas A. Kufer, Mathias Chamaillard
Published 2018-12-01

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

by Sofie Voet, Conor Mc Guire, Nora Hagemeyer, Arne Martens, Anna Schroeder, Peter Wieghofer, Carmen Daems, Ori Staszewski, Lieselotte Vande Walle, Marta Joana Costa Jordao, Mozes Sze, Hanna-Kaisa Vikkula, Delphine Demeestere, Griet Van Imschoot, Charlotte L. Scott, Esther Hoste, Amanda Gonçalves, Martin Guilliams, Saskia Lippens, Claude Libert, Roos E. Vandenbroucke, Ki-Wook Kim, Steffen Jung, Zsuzsanna Callaerts-Vegh, Patrick Callaerts, Joris de Wit, Mohamed Lamkanfi, Marco Prinz, Geert van Loo
Published 2018-05-01

Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes

by Anastasiia Gainullina, Denis A. Mogilenko, Li-Hao Huang, Helena Todorov, Vipin Narang, Ki-Wook Kim, Lim Sheau Yng, Andrew Kent, Baosen Jia, Kumba Seddu, Karen Krchma, Jun Wu, Karine Crozat, Elena Tomasello, Regine Dress, Peter See, Charlotte Scott, Sophie Gibbings, Geetika Bajpai, Jigar V. Desai, Barbara Maier, Sébastien This, Peter Wang, Stephanie Vargas Aguilar, Lucie Poupel, Sébastien Dussaud, Tyng-An Zhou, Veronique Angeli, J. Magarian Blander, Kyunghee Choi, Marc Dalod, Ivan Dzhagalov, Emmanuel L. Gautier, Claudia Jakubzick, Kory Lavine, Michail S. Lionakis, Helena Paidassi, Michael H. Sieweke, Florent Ginhoux, Martin Guilliams, Christophe Benoist, Miriam Merad, Gwendalyn J. Randolph, Alexey Sergushichev, Maxim N. Artyomov
Published 2023-02-01