β-Cell Pathophysiology: A Review of Advanced Optical Microscopy Applications

by Gianmarco Ferri, Luca Pesce, Marta Tesi, Piero Marchetti, Francesco Cardarelli
Published 2021-11-01

Metabolic response of Insulinoma 1E cells to glucose stimulation studied by fluorescence lifetime imaging

by Gianmarco Ferri, Marta Tesi, Federico Massarelli, Lorella Marselli, Piero Marchetti, Francesco Cardarelli
Published 2020-07-01

Arginase 2 and Polyamines in Human Pancreatic Beta Cells: Possible Role in the Pathogenesis of Type 2 Diabetes

by Lorella Marselli, Emanuele Bosi, Carmela De Luca, Silvia Del Guerra, Marta Tesi, Mara Suleiman, Piero Marchetti
Published 2021-11-01

Machine-learning-guided recognition of α and β cells from label-free infrared micrographs of living human islets of Langerhans

by Fabio Azzarello, Francesco Carli, Valentina De Lorenzi, Marta Tesi, Piero Marchetti, Fabio Beltram, Francesco Raimondi, Francesco Cardarelli
Published 2024-06-01

Unveiling nanoscale optical signatures of cytokine-induced β-cell dysfunction

by Licia Anna Pugliese, Valentina De Lorenzi, Mario Bernardi, Samuele Ghignoli, Marta Tesi, Piero Marchetti, Luca Pesce, Francesco Cardarelli
Published 2023-08-01

Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets

by Fabio Azzarello, Luca Pesce, Valentina De Lorenzi, Gianmarco Ferri, Marta Tesi, Silvia Del Guerra, Piero Marchetti, Francesco Cardarelli
Published 2022-11-01

The Role of Beta Cell Recovery in Type 2 Diabetes Remission

by Mara Suleiman, Lorella Marselli, Miriam Cnop, Decio L. Eizirik, Carmela De Luca, Francesca R. Femia, Marta Tesi, Silvia Del Guerra, Piero Marchetti
Published 2022-07-01

Spatiotemporal Correlation Spectroscopy Reveals a Protective Effect of Peptide-Based GLP-1 Receptor Agonism against Lipotoxicity on Insulin Granule Dynamics in Primary Human β-Cell...

by Gianmarco Ferri, Marta Tesi, Luca Pesce, Marco Bugliani, Francesca Grano, Margherita Occhipinti, Mara Suleiman, Carmela De Luca, Lorella Marselli, Piero Marchetti, Francesco Cardarelli
Published 2021-09-01

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis

by Marta Tesi, Marco Bugliani, Gianmarco Ferri, Mara Suleiman, Carmela De Luca, Emanuele Bosi, Matilde Masini, Vincenzo De Tata, Conny Gysemans, Francesco Cardarelli, Miriam Cnop, Decio L. Eizirik, Piero Marchetti, Lorella Marselli
Published 2021-02-01

The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved

by Laura Giusti, Marta Tesi, Federica Ciregia, Lorella Marselli, Lorenzo Zallocco, Mara Suleiman, Carmela De Luca, Silvia Del Guerra, Mariachiara Zuccarini, Marco Trerotola, Decio L. Eizirik, Miriam Cnop, Maria R. Mazzoni, Piero Marchetti, Antonio Lucacchini, Maurizio Ronci
Published 2022-08-01

Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes

by Lorella Marselli, Anthony Piron, Mara Suleiman, Maikel L. Colli, Xiaoyan Yi, Amna Khamis, Gaelle R. Carrat, Guy A. Rutter, Marco Bugliani, Laura Giusti, Maurizio Ronci, Mark Ibberson, Jean-Valery Turatsinze, Ugo Boggi, Paolo De Simone, Vincenzo De Tata, Miguel Lopes, Daniela Nasteska, Carmela De Luca, Marta Tesi, Emanuele Bosi, Pratibha Singh, Daniela Campani, Anke M. Schulte, Michele Solimena, Peter Hecht, Brian Rady, Ivona Bakaj, Alessandro Pocai, Lisa Norquay, Bernard Thorens, Mickaël Canouil, Philippe Froguel, Decio L. Eizirik, Miriam Cnop, Piero Marchetti
Published 2020-12-01