PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells.

by Brian Rady, Takahiro Nishio, Debanjan Dhar, Xiao Liu, Mark Erion, Tatiana Kisseleva, David A Brenner, Alessandro Pocai
Published 2021-01-01

PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells

by Brian Rady, Takahiro Nishio, Debanjan Dhar, Xiao Liu, Mark Erion, Tatiana Kisseleva, David A. Brenner, Alessandro Pocai
Published 2021-01-01

The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR

by Janos Steffen, Jennifer Ngo, Sheng-Ping Wang, Kevin Williams, Henning F. Kramer, George Ho, Carlos Rodriguez, Krishna Yekkala, Chidozie Amuzie, Russell Bialecki, Lisa Norquay, Andrea R. Nawrocki, Mark Erion, Alessandro Pocai, Orian S. Shirihai, Marc Liesa
Published 2022-10-01

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

by Santhosh Satapati, Ying Qian, Margaret S. Wu, Aleksandr Petrov, Ge Dai, Sheng-ping Wang, Yonghua Zhu, Xiaolan Shen, Eric S. Muise, Ying Chen, Emanuel Zycband, Adam Weinglass, Jerry Di Salvo, John S. Debenham, Jason M. Cox, Ping Lan, Vinit Shah, Stephen F. Previs, Mark Erion, David E. Kelley, Liangsu Wang, Andrew D. Howard, Jin Shang
Published 2017-08-01