The Final Link: Tapping the Power of Chemical Genetics to Connect the Molecular and Biologic Functions of Mitotic Protein Kinases

by Mark E. Burkard, Robert F. Lera
Published 2012-10-01

Photosensitive lichenoid skin reaction to capecitabine

by Rena A. Shah, Daniel D. Bennett, Mark E. Burkard
Published 2017-12-01

Update on Adjuvant Chemotherapy for Early Breast Cancer

by Murtuza M. Rampurwala, Gabrielle B. Rocque, Mark E. Burkard
Published 2014-10-01

Update on Adjuvant Chemotherapy for Early Breast Cancer

by Murtuza M. Rampurwala, Gabrielle B. Rocque, Mark E. Burkard
Published 2014-01-01

Increased Aurora B expression reduces substrate phosphorylation and induces chromosomal instability

by Eric M. C. Britigan, Jun Wan, Daniel K. Sam, Sarah E. Copeland, Amber L. Lasek, Laura C. F. Hrycyniak, Lei Wang, Anjon Audhya, Anjon Audhya, Anjon Audhya, Mark E. Burkard, Mark E. Burkard, Mark E. Burkard, Avtar Roopra, Beth A. Weaver, Beth A. Weaver, Beth A. Weaver
Published 2022-10-01

Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.

by Hyunjung Kim, James M Johnson, Robert F Lera, Sarang Brahma, Mark E Burkard
Published 2017-01-01

The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation.

by Amber L Lasek, Brittany M McPherson, Natalie G Trueman, Mark E Burkard
Published 2016-01-01

CHARTS: a web application for characterizing and comparing tumor subpopulations in publicly available single-cell RNA-seq data sets

by Matthew N. Bernstein, Zijian Ni, Michael Collins, Mark E. Burkard, Christina Kendziorski, Ron Stewart
Published 2021-02-01

Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference

by Andrew R Lynch, Nicholas L Arp, Amber S Zhou, Beth A Weaver, Mark E Burkard
Published 2022-04-01

A physician-scientist preceptorship in clinical and translational research enhances training and mentorship

by Jonathan A. Stefely, Erin Theisen, Chelsea Hanewall, Linda Scholl, Mark E. Burkard, Anna Huttenlocher, John-Paul J. Yu
Published 2019-03-01

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instabilit...

by Daniel R. Matson, Ryan A. Denu, Lauren M. Zasadil, Mark E. Burkard, Beth A. Weaver, Christopher Flynn, P. Todd Stukenberg
Published 2021-02-01

Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles.

by Amber S Zhou, John B Tucker, Christina M Scribano, Andrew R Lynch, Caleb L Carlsen, Sophia T Pop-Vicas, Srishrika M Pattaswamy, Mark E Burkard, Beth A Weaver
Published 2023-10-01

Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles

by Amber S. Zhou, John B. Tucker, Christina M. Scribano, Andrew R. Lynch, Caleb L. Carlsen, Sophia T. Pop-Vicas, Srishrika M. Pattaswamy, Mark E. Burkard, Beth A. Weaver
Published 2023-10-01

Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer

by Ashok Singh, Ryan A. Denu, Serena K. Wolfe, Jamie M. Sperger, Jennifer Schehr, Tessa Witkowsky, Karla Esbona, Richard J. Chappell, Beth A. Weaver, Mark E. Burkard, Joshua M. Lang
Published 2020-08-01

Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

by Mark E Burkard, John Maciejowski, Verónica Rodriguez-Bravo, Michael Repka, Drew M Lowery, Karl R Clauser, Chao Zhang, Kevan M Shokat, Steven A Carr, Michael B Yaffe, Prasad V Jallepalli
Published 2009-05-01

Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment

by Joe T. Sharick, Joe T. Sharick, Christine M. Walsh, Carley M. Sprackling, Cheri A. Pasch, Dan L. Pham, Dan L. Pham, Karla Esbona, Alka Choudhary, Alka Choudhary, Rebeca Garcia-Valera, Rebeca Garcia-Valera, Rebeca Garcia-Valera, Mark E. Burkard, Mark E. Burkard, Stephanie M. McGregor, Stephanie M. McGregor, Kristina A. Matkowskyj, Kristina A. Matkowskyj, Kristina A. Matkowskyj, Alexander A. Parikh, Ingrid M. Meszoely, Mark C. Kelley, Susan Tsai, Dustin A. Deming, Dustin A. Deming, Dustin A. Deming, Melissa C. Skala, Melissa C. Skala, Melissa C. Skala
Published 2020-05-01

Development and validation of an integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit

by Scott A. Tomlins, Nickolay A. Khazanov, Benjamin J. Bulen, Daniel H. Hovelson, Melissa J. Shreve, Laura E. Lamb, Marc R. Matrana, Mark E. Burkard, Eddy Shih-Hsin Yang, William Jeffery Edenfield, E. Claire Dees, Adedayo A. Onitilo, Michael Thompson, Gary L. Buchschacher, Alan M. Miller, Alexander Menter, Benjamin Parsons, Timothy Wassenaar, Leon C. Hwang, J. Marie Suga, Robert Siegel, William Irvin, Suresh Nair, Jennifer N. Slim, Jamal Misleh, Jamil Khatri, Gregory Masters, Sachdev Thomas, Malek Safa, Daniel M. Anderson, Kat Kwiatkowski, Khalis Mitchell, Tina Hu-Seliger, Stephanie Drewery, Andrew Fischer, Komal Plouffe, Eric Czuprenski, Jennifer Hipp, Travis Reeder, Hana Vakil, D. Bryan Johnson, Daniel R. Rhodes
Published 2023-02-01