SPEN, a new player in primary cilia formation and cell migration in breast cancer

by Stéphanie Légaré, Catherine Chabot, Mark Basik
Published 2017-09-01

Integration of genomic technologies for accelerated cancer drug development

by Mark Basik, Spyro Mousses, Jeffrey Trent
Published 2003-09-01

Sequential use of Antibiotics and Adjuvant Chemotherapy Leading to a Fatal Pseudomembranous Colitis

by Mark Basik, Barbara Roback, Marc Trudeau
Published 2020-12-01

Precision Medicine Tools to Guide Therapy and Monitor Response to Treatment in a HER-2+ Gastric Cancer Patient: Case Report

by Adriana Aguilar-Mahecha, Sarah Joseph, Luca Cavallone, Marguerite Buchanan, Urszula Krzemien, Gerald Batist, Gerald Batist, Mark Basik, Mark Basik
Published 2019-08-01

A micro-flow, high-pH, reversed-phase peptide fractionation and collection system for targeted and in-depth proteomics of low-abundance proteins in limiting samples

by Marta Zurawska, Mark Basik, Adriana Aguilar-Mahecha, Michal Dadlez, Dominik Domanski
Published 2023-12-01

The effect of pre-analytical variability on the measurement of MRM-MS-based mid- to high-abundance plasma protein biomarkers and a panel of cytokines.

by Adriana Aguilar-Mahecha, Michael A Kuzyk, Dominik Domanski, Christoph H Borchers, Mark Basik
Published 2012-01-01

Monoallelic chromatin conformation flanking long-range silenced domains in cancer-derived and normal cells.

by Domenic Di Paola, John Raelson, Emmanouil Rampakakis, Mark Basik, Maria Zannis-Hadjopoulos, W Edward C Bradley
Published 2013-01-01

RSF1 and not cyclin D1 gene amplification may predict lack of benefit from adjuvant tamoxifen in high-risk pre-menopausal women in the MA.12 randomized clinical trial.

by Dana Keilty, Marguerite Buchanan, Katerina Ntapolias, Olga Aleynikova, Dongsheng Tu, Xiao Li, Lois Shepherd, Vivien Bramwell, Mark Basik
Published 2013-01-01

Early, On-Treatment Levels and Dynamic Changes of Genomic Instability in Circulating Tumor DNA Predict Response to Treatment and Outcome in Metastatic Breast Cancer Patients

by Adriana Aguilar-Mahecha, Josiane Lafleur, Susie Brousse, Olga Savichtcheva, Kimberly A. Holden, Nathan Faulkner, Graham McLennan, Taylor J. Jensen, Mark Basik
Published 2021-03-01

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

by Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux
Published 2020-08-01

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

by Alison Hirukawa, Harvey W. Smith, Dongmei Zuo, Catherine R. Dufour, Paul Savage, Nicholas Bertos, Radia M. Johnson, Tung Bui, Guillaume Bourque, Mark Basik, Vincent Giguère, Morag Park, William J. Muller
Published 2018-06-01

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy

by Cedric Darini, Nour Ghaddar, Catherine Chabot, Gloria Assaker, Siham Sabri, Shuo Wang, Jothilatha Krishnamoorthy, Marguerite Buchanan, Adriana Aguilar-Mahecha, Bassam Abdulkarim, Jean Deschenes, Jose Torres, Josie Ursini-Siegel, Mark Basik, Antonis E. Koromilas
Published 2019-05-01

A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens

by Georgia Mitsa, Qianyu Guo, Christophe Goncalves, Samuel E. J. Preston, Vincent Lacasse, Adriana Aguilar-Mahecha, Naciba Benlimame, Mark Basik, Alan Spatz, Gerald Batist, Wilson H. Miller, Sonia V. del Rincon, René P. Zahedi, Christoph H. Borchers
Published 2022-04-01

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

by Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie-Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury, William J. Muller, Morag Park, Philippe P. Roux, Jean-Philippe Gratton, Jean-François Côté
Published 2018-05-01

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

by Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie-Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury, William J. Muller, Morag Park, Philippe P. Roux, Jean-Philippe Gratton, Jean-François Côté
Published 2023-12-01

The Mutational Spectrum of Pre- and Post-Neoadjuvant Chemotherapy Triple-Negative Breast Cancers

by Adriana Aguilar-Mahecha, Najmeh Alirezaie, Josiane Lafleur, Eric Bareke, Ewa Przybytkowski, Cathy Lan, Luca Cavallone, Myriam Salem, Manuela Pelmus, Olga Aleynikova, Celia Greenwood, Amanda Lovato, Cristiano Ferrario, Jean-François Boileau, Catalin Mihalcioiu, Josée-Anne Roy, Elizabeth Marcus, Federico Discepola, Jacek Majewski, Mark Basik
Published 2023-12-01

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer

by Paul Savage, Alexis Blanchet-Cohen, Timothée Revil, Dunarel Badescu, Sadiq M.I. Saleh, Yu-Chang Wang, Dongmei Zuo, Leah Liu, Nicholas R. Bertos, Valentina Munoz-Ramos, Mark Basik, Kevin Petrecca, Jamil Asselah, Sarkis Meterissian, Marie-Christine Guiot, Atilla Omeroglu, Claudia L. Kleinman, Morag Park, Jiannis Ragoussis
Published 2017-10-01

STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer

by Stephanie P. Totten, Young Kyuen Im, Eduardo Cepeda Cañedo, Ouafa Najyb, Alice Nguyen, Steven Hébert, Ryuhjin Ahn, Kyle Lewis, Benjamin Lebeau, Rachel La Selva, Valérie Sabourin, Constanza Martínez, Paul Savage, Hellen Kuasne, Daina Avizonis, Nancy Santos Martínez, Catherine Chabot, Adriana Aguilar-Mahecha, Marie-Line Goulet, Matthew Dankner, Michael Witcher, Kevin Petrecca, Mark Basik, Michael Pollak, Ivan Topisirovic, Rongtuan Lin, Peter M. Siegel, Claudia L. Kleinman, Morag Park, Julie St-Pierre, Josie Ursini-Siegel
Published 2021-06-01

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

by Harvey W. Smith, Alison Hirukawa, Virginie Sanguin-Gendreau, Ipshita Nandi, Catherine R. Dufour, Dongmei Zuo, Kristofferson Tandoc, Matthew Leibovitch, Salendra Singh, Jonathan P. Rennhack, Matthew Swiatnicki, Cynthia Lavoie, Vasilios Papavasiliou, Carolin Temps, Neil O. Carragher, Asier Unciti-Broceta, Paul Savage, Mark Basik, Vincent van Hoef, Ola Larsson, Caroline L. Cooper, Ana Cristina Vargas Calderon, Jane Beith, Ewan Millar, Christina Selinger, Vincent Giguère, Morag Park, Lyndsay N. Harris, Vinay Varadan, Eran R. Andrechek, Sandra A. O’Toole, Ivan Topisirovic, William J. Muller
Published 2019-07-01

Chromosome-breakage genomic instability and chromothripsis in breast cancer

by Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia MT, Basik, Mark
Published 2014