MAPK15 controls mitochondrial fitness and contributes to prevent cellular senescence

by Lorenzo Franci, Giovanni Inzalaco, Mario Chiariello
Published 2022-12-01

Overcoming challenges in glioblastoma treatment: targeting infiltrating cancer cells and harnessing the tumor microenvironment

by Mario Chiariello, Mario Chiariello, Giovanni Inzalaco, Giovanni Inzalaco, Giovanni Inzalaco, Virginia Barone, Lisa Gherardini, Lisa Gherardini
Published 2023-12-01

MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis

by Silvia Pietrobono, Lorenzo Franci, Francesco Imperatore, Cristina Zanini, Barbara Stecca, Mario Chiariello
Published 2021-09-01

RAB7A Regulates Vimentin Phosphorylation through AKT and PAK

by Roberta Romano, Matteo Calcagnile, Azzurra Margiotta, Lorenzo Franci, Mario Chiariello, Pietro Alifano, Cecilia Bucci
Published 2021-05-01

Structure prediction and validation of the ERK8 kinase domain.

by Angela Strambi, Mattia Mori, Matteo Rossi, David Colecchia, Fabrizio Manetti, Francesca Carlomagno, Maurizio Botta, Mario Chiariello
Published 2013-01-01

NCOA4 Deficiency Impairs Systemic Iron Homeostasis

by Roberto Bellelli, Giorgia Federico, Alessandro Matte’, David Colecchia, Achille Iolascon, Mario Chiariello, Massimo Santoro, Lucia De Franceschi, Francesca Carlomagno
Published 2016-01-01

HrpA anchors meningococci to the dynein motor and affects the balance between apoptosis and pyroptosis

by Adelfia Talà, Flora Guerra, Matteo Calcagnile, Roberta Romano, Silvia Caterina Resta, Aurora Paiano, Mario Chiariello, Graziano Pizzolante, Cecilia Bucci, Pietro Alifano
Published 2022-06-01

Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

by Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta
Published 2019-01-01

Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML

by Leire Iralde-Lorente, Giusy Tassone, Ylenia Cau, Claire Munier, Lorenzo Franci, Cecilia Pozzi, Adriano Angelucci, Mario Chiariello, Matthew Perry, Stefano Mangani, Maurizio Botta
Published 2019-08-01

The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models

by Lisa Gherardini, Giovanni Inzalaco, Francesco Imperatore, Romina D’Aurizio, Lorenzo Franci, Vincenzo Miragliotta, Adele Boccuto, Pierpaolo Calandro, Matteo Andreini, Alessia Tarditi, Mario Chiariello
Published 2021-09-01

MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes

by Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, Mario Chiariello
Published 2024-06-01

Superior Properties of N-Acetylcysteine Ethyl Ester over N-Acetyl Cysteine to Prevent Retinal Pigment Epithelial Cells Oxidative Damage

by Gian Marco Tosi, Daniela Giustarini, Lorenzo Franci, Alberto Minetti, Francesco Imperatore, Elena Caldi, Paolo Fiorenzani, Anna Maria Aloisi, Anna Sparatore, Ranieri Rossi, Mario Chiariello, Maurizio Orlandini, Federico Galvagni
Published 2021-01-01

Co-Expression of Podoplanin and CD44 in Proliferative Vitreoretinopathy Epiretinal Membranes

by Denise Bonente, Laura Bianchi, Rossana De Salvo, Claudio Nicoletti, Elena De Benedetto, Tommaso Bacci, Luca Bini, Giovanni Inzalaco, Lorenzo Franci, Mario Chiariello, Gian Marco Tosi, Eugenio Bertelli, Virginia Barone
Published 2023-06-01

Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models

by Lisa Gherardini, Veronica Vetri Buratti, Mirko Maturi, Giovanni Inzalaco, Erica Locatelli, Letizia Sambri, Sara Gargiulo, Virginia Barone, Denise Bonente, Eugenio Bertelli, Silvia Tortorella, Lorenzo Franci, Antonio Fioravanti, Mauro Comes Franchini, Mario Chiariello
Published 2023-03-01

Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models

by Annalaura Brai, Valentina Riva, Letizia Clementi, Lucia Falsitta, Claudio Zamperini, Virginia Sinigiani, Claudio Festuccia, Samantha Sabetta, Davide Aiello, Camilla Roselli, Anna Garbelli, Claudia Immacolata Trivisani, Laura Maccari, Francesca Bugli, Maurizio Sanguinetti, Pierpaolo Calandro, Mario Chiariello, Paola Quaranta, Lorenzo Botta, Adriano Angelucci, Giovanni Maga, Maurizio Botta
Published 2021-11-01