Increasing the Clinical Potential and Applications of Anti-HIV Antibodies

by Casey K. Hua, Margaret E. Ackerman, Margaret E. Ackerman
Published 2017-11-01

Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function

by Andrew R. Crowley, Margaret E. Ackerman, Margaret E. Ackerman
Published 2019-04-01

Leveraging permutation testing to assess confidence in positive-unlabeled learning applied to high-dimensional biological datasets

by Shiwei Xu, Margaret E. Ackerman
Published 2024-06-01

Foundations for improved vaccine correlate of risk analysis using positive-unlabeled learning

by Natasha S. Kelkar, Kyle S. Morrison, Margaret E. Ackerman
Published 2023-01-01

Positive-unlabeled learning to infer protection status and identify correlates in vaccine efficacy field trials

by Shiwei Xu, Natasha S. Kelkar, Margaret E. Ackerman
Published 2024-03-01

Coming together at the hinges: Therapeutic prospects of IgG3

by Thach H. Chu, Edward F. Patz, Margaret E. Ackerman
Published 2021-01-01

Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies.

by Sebastian K Grimm, Michael B Battles, Margaret E Ackerman
Published 2015-01-01

Protein-protein fusion catalyzed by sortase A.

by David A Levary, Ranganath Parthasarathy, Eric T Boder, Margaret E Ackerman
Published 2011-01-01

Toward high-throughput engineering techniques for improving CAR intracellular signaling domains

by Savannah E. Butler, Savannah E. Butler, Colin J. Hartman, Colin J. Hartman, Yina H. Huang, Yina H. Huang, Margaret E. Ackerman, Margaret E. Ackerman
Published 2023-03-01

Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals

by Savannah E. Butler, Andrew R. Crowley, Harini Natarajan, Shiwei Xu, Joshua A. Weiner, Carly A. Bobak, Daniel E. Mattox, Jiwon Lee, Wendy Wieland-Alter, Ruth I. Connor, Peter F. Wright, Margaret E. Ackerman, Margaret E. Ackerman, Margaret E. Ackerman
Published 2021-01-01

Monoclonal antibody therapy of herpes simplex virus: An opportunity to decrease congenital and perinatal infections

by Iara M. Backes, Iara M. Backes, David A. Leib, Margaret E. Ackerman
Published 2022-08-01

Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?

by David R Martinez, Genevieve G Fouda, Xinxia Peng, Margaret E Ackerman, Sallie R Permar
Published 2018-08-01

Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors

by Andrew R. Crowley, Nana Yaw Osei-Owusu, Gillian Dekkers, Wenda Gao, Manfred Wuhrer, Diogo M. Magnani, Keith A. Reimann, Seth H. Pincus, Seth H. Pincus, Gestur Vidarsson, Margaret E. Ackerman, Margaret E. Ackerman
Published 2021-10-01

Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity.

by John W Lamppa, Margaret E Ackerman, Jennifer I Lai, Thomas C Scanlon, Karl E Griswold
Published 2011-02-01

Computationally-driven identification of antibody epitopes

by Casey K Hua, Albert T Gacerez, Charles L Sentman, Margaret E Ackerman, Yoonjoo Choi, Chris Bailey-Kellogg
Published 2017-12-01

Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques

by Natasha S. Kelkar, Benjamin S. Goldberg, Jérémy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J. Hessell, Margaret E. Ackerman
Published 2024-03-01

Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG

by Andrew R. Crowley, Matthew R. Mehlenbacher, Mohammad M. Sajadi, Anthony L. DeVico, George K. Lewis, Margaret E. Ackerman
Published 2023-12-01

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

by Benjamin S. Goldberg, Chengzi I. Kaku, Jérémy Dufloo, Timothée Bruel, Olivier Schwartz, David A. Spencer, Ann J. Hessell, Margaret E. Ackerman
Published 2021-10-01

Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control.

by Margaret E Ackerman, Anastassia Mikhailova, Eric P Brown, Karen G Dowell, Bruce D Walker, Chris Bailey-Kellogg, Todd J Suscovich, Galit Alter
Published 2016-01-01

Immunoprofiling Correlates of Protection Against SHIV Infection in Adjuvanted HIV-1 Pox-Protein Vaccinated Rhesus Macaques

by Pinyi Lu, Pinyi Lu, Dylan J. Guerin, Shu Lin, Sidhartha Chaudhury, Margaret E. Ackerman, Diane L. Bolton, Diane L. Bolton, Anders Wallqvist
Published 2021-05-01