Gene Panel Tumor Testing in Ovarian Cancer Patients Significantly Increases the Yield of Clinically Actionable Germline Variants beyond <i>BRCA1</i>/<i>BRCA2</i>

by Ana Barbosa, Pedro Pinto, Ana Peixoto, Joana Guerra, Carla Pinto, Catarina Santos, Manuela Pinheiro, Carla Escudeiro, Carla Bartosch, João Silva, Manuel R. Teixeira
Published 2020-09-01

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.

by Sofia Maia, Marta Cardoso, Pedro Pinto, Manuela Pinheiro, Catarina Santos, Ana Peixoto, Maria José Bento, Jorge Oliveira, Rui Henrique, Carmen Jerónimo, Manuel R Teixeira
Published 2015-01-01

Molecular characterization of the MLL-SEPT6 fusion gene in acute myeloid leukemia: identification of novel fusion transcripts and cloning of genomic breakpoint junctions

by Nuno Cerveira, Francesca Micci, Joana Santos, Manuela Pinheiro, Cecília Correia, Susana Lisboa, Susana Bizarro, Lucília Norton, Anders Glomstein, Ann E. Åsberg, Sverre Heim, Manuel R. Teixeira
Published 2008-07-01

Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas.

by Pedro Pinto, Ana Peixoto, Catarina Santos, Patrícia Rocha, Carla Pinto, Manuela Pinheiro, Luís Leça, Ana Teresa Martins, Verónica Ferreira, Carla Bartosch, Manuel R Teixeira, Manuel R Teixeira
Published 2016-01-01

Good news about good news? The limited impacts of informing Americans about recent success in climate change mitigation

by Olivia Chiancone, Tara Chugh, Brayant De Leon-Duarte, Andrew C. Eggers, Benjamin Fica, Ishaan Goel, Stacia Konow, Annika Lundsgaard, Julia Margie, Zane Miller, Manuela Pinheiro, Panteleymon Semka, John Stokes, Leena Tantawy, Panthita Triamkitsawat, Gus Waldspurger
Published 2024-05-01

Germline MLH1, MSH2 and MSH6 variants in Brazilian patients with colorectal cancer and clinical features suggestive of Lynch Syndrome

by Nayê Balzan Schneider, Tatiane Pastor, André Escremim de Paula, Maria Isabel Achatz, Ândrea Ribeiro dos Santos, Fernanda Sales Luiz Vianna, Clévia Rosset, Manuela Pinheiro, Patricia Ashton‐Prolla, Miguel Ângelo Martins Moreira, Edenir Inêz Palmero, Brazilian Lynch Syndrome Study Group
Published 2018-05-01

Frequency of <i>CDH1, CTNNA1</i> and <i>CTNND1</i> Germline Variants in Families with Diffuse and Mixed Gastric Cancer

by Joana Guerra, Carla Pinto, Pedro Pinto, Manuela Pinheiro, Catarina Santos, Ana Peixoto, Carla Escudeiro, Ana Barbosa, Miguel Porto, Inês Francisco, Paula Lopes, Ana Raquel Isidoro, Ana Luísa Cunha, Cristina Albuquerque, Isabel Claro, Carla Oliveira, João Silva, Manuel R. Teixeira
Published 2023-08-01

Combined germline and tumor mutation signature testing identifies new families with NTHL1 tumor syndrome

by Carla Pinto, Carla Pinto, Carla Pinto, Joana Guerra, Joana Guerra, Manuela Pinheiro, Carla Escudeiro, Carla Escudeiro, Catarina Santos, Catarina Santos, Pedro Pinto, Miguel Porto, Carla Bartosch, Carla Bartosch, João Silva, João Silva, Ana Peixoto, Ana Peixoto, Manuel R. Teixeira, Manuel R. Teixeira, Manuel R. Teixeira
Published 2023-08-01

Next Generation Sequencing of Tumor and Matched Plasma Samples: Identification of Somatic Variants in ctDNA From Ovarian Cancer Patients

by Ana Barbosa, Ana Barbosa, Pedro Pinto, Ana Peixoto, Ana Peixoto, Joana Guerra, Manuela Pinheiro, Catarina Santos, Catarina Santos, Carla Pinto, Carla Pinto, Carla Escudeiro, Carla Escudeiro, Carla Bartosch, Rui Santos, Andreia Brandão, João Silva, João Silva, Manuel R. Teixeira, Manuel R. Teixeira, Manuel R. Teixeira
Published 2021-09-01

BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome

by Ingrid Petroni Ewald, Silvia Liliana Cossio, Edenir Inez Palmero, Manuela Pinheiro, Ivana Lucia de Oliveira Nascimento, Taisa Manuela Bonfim Machado, Kiyoko Abe Sandes, Betânia Toralles, Bernardo Garicochea, Patricia Izetti, Maria Luiza Saraiva Pereira, Hugo Bock, Fernando Regla Vargas, Miguel Ângelo Martins Moreira, Ana Peixoto, Manuel R. Teixeira, Patricia Ashton-Prolla
Published 2016-06-01

BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome

by Ingrid Petroni Ewald, Silvia Liliana Cossio, Edenir Inez Palmero, Manuela Pinheiro, Ivana Lucia de Oliveira Nascimento, Taisa Manuela Bonfim Machado, Kiyoko Abe Sandes, Betânia Toralles, Bernardo Garicochea, Patricia Izetti, Maria Luiza Saraiva Pereira, Hugo Bock, Fernando Regla Vargas, Miguel Ângelo Martins Moreira, Ana Peixoto, Manuel R. Teixeira, Patricia Ashton-Prolla
Published 2016-06-01

Correspondence: SEMA4A variation and risk of colorectal cancer

by Ben Kinnersley, Daniel Chubb, Sara E. Dobbins, Matthew Frampton, Stephan Buch, Maria N. Timofeeva, Sergi Castellví-Bel, Susan M. Farrington, Asta Forsti, Jochen Hampe, Kari Hemminki, Robert M. W. Hofstra, Emma Northwood, Claire Palles, Manuela Pinheiro, Clara Ruiz-Ponte, Clemens Schafmayer, Manuel R. Teixeira, Helga Westers, Tom van Wezel, D. Timothy Bishop, Ian Tomlinson, Malcolm G. Dunlop, Richard S. Houlston
Published 2016-03-01

Tumor Testing for Somatic and Germline BRCA1/BRCA2 Variants in Ovarian Cancer Patients in the Context of Strong Founder Effects

by Ana Peixoto, Ana Peixoto, Pedro Pinto, Joana Guerra, Manuela Pinheiro, Catarina Santos, Catarina Santos, Carla Pinto, Carla Pinto, Rui Santos, Carla Escudeiro, Carla Bartosch, Carla Bartosch, Rita Canário, Rita Canário, Rita Canário, Rita Canário, Ana Barbosa, Alfredo Gouveia, Almerinda Petiz, Miguel Henriques Abreu, Susana Sousa, Deolinda Pereira, João Silva, João Silva, Manuel R. Teixeira, Manuel R. Teixeira, Manuel R. Teixeira
Published 2020-07-01

Multiple TP53 p.R337H haplotypes and implications for tumor susceptibility

by Emilia M. Pinto, Cintia Fridman, Bonald C. Figueiredo, Hector Salvador, Manuel R. Teixeira, Carla Pinto, Manuela Pinheiro, Christian P. Kratz, Cinzia Lavarino, Edith A.M. F. Legal, Anh Le, Gregory Kelly, Erika Koeppe, Elena M. Stoffel, Kelsey Breen, Stefanie Hahner, Britta Heinze, Piti Techavichit, Amanda Krause, Tsutomu Ogata, Yasuko Fujisawa, Michael F. Walsh, Huma Q. Rana, Kara N. Maxwell, Judy E. Garber, Carlos Rodriguez-Galindo, Raul C. Ribeiro, Gerard P. Zambetti
Published 2024-01-01

Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project

by Ana Peixoto, Luís Cirnes, Ana Luísa Carvalho, Maria João Andrade, Maria José Brito, Paula Borralho, Paula Borralho, Nuno Coimbra, Pedro M. Borralho, Ana Sofia Carneiro, Lisandra Castro, Lurdes Correia, Lurdes Correia, Maria Rita Dionísio, Carlos Faria, Paulo Figueiredo, Ana Gomes, Joana Paixão, Manuela Pinheiro, Hugo Prazeres, Joana Ribeiro, Natália Salgueiro, Fernando. C Schmitt, Fernando. C Schmitt, Fátima Silva, Fátima Silva, Fátima Silva, Ana Rita Silvestre, Ana Carla Sousa, Joana Almeida-Tavares, Manuel R. Teixeira, Manuel R. Teixeira, Saudade André, Jose Carlos Machado, Jose Carlos Machado
Published 2024-04-01

Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project

by Ana Peixoto, Luís Cirnes, Ana Luísa Carvalho, Maria João Andrade, Maria José Brito, Paula Borralho, Paula Borralho, Nuno Coimbra, Pedro M. Borralho, Ana Sofia Carneiro, Lisandra Castro, Lurdes Correia, Lurdes Correia, Maria Rita Dionísio, Carlos Faria, Paulo Figueiredo, Ana Gomes, Joana Paixão, Manuela Pinheiro, Hugo Prazeres, Joana Ribeiro, Natália Salgueiro, Fernando C. Schmitt, Fernando C. Schmitt, Fátima Silva, Fátima Silva, Fátima Silva, Ana Rita Silvestre, Ana Carla Sousa, Joana Almeida-Tavares, Manuel R. Teixeira, Manuel R. Teixeira, Saudade André, José Carlos Machado, José Carlos Machado
Published 2023-02-01

The <i>CHEK2</i> Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor

by Andreia Brandão, Paula Paulo, Sofia Maia, Manuela Pinheiro, Ana Peixoto, Marta Cardoso, Maria P. Silva, Catarina Santos, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth Muir, UKGPCS Collaborators, Johanna Schleutker, Ying Wang, Nora Pashayan, Jyotsna Batra, APCB BioResource, Henrik Grönberg, David E. Neal, Børge G. Nordestgaard, Catherine M. Tangen, Melissa C. Southey, Alicja Wolk, Demetrius Albanes, Christopher A. Haiman, Ruth C. Travis, Janet L. Stanford, Lorelei A. Mucci, Catharine M. L. West, Sune F. Nielsen, Adam S. Kibel, Olivier Cussenot, Sonja I. Berndt, Stella Koutros, Karina Dalsgaard Sørensen, Cezary Cybulski, Eli Marie Grindedal, Jong Y. Park, Sue A. Ingles, Christiane Maier, Robert J. Hamilton, Barry S. Rosenstein, Ana Vega, The IMPACT Study Steering Committee and Collaborators, Manolis Kogevinas, Fredrik Wiklund, Kathryn L. Penney, Hermann Brenner, Esther M. John, Radka Kaneva, Christopher J. Logothetis, Susan L. Neuhausen, Kim De Ruyck, Azad Razack, Lisa F. Newcomb, Canary PASS Investigators, Davor Lessel, Nawaid Usmani, Frank Claessens, Manuela Gago-Dominguez, Paul A. Townsend, Monique J. Roobol, The Profile Study Steering Committee, The PRACTICAL Consortium, Manuel R. Teixeira
Published 2020-11-01