Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models

by Laura Magri, Manuela Cominelli, Marco Cambiaghi, Marco Cursi, Letizia Leocani, Fabio Minicucci, Pietro Luigi Poliani, Rossella Galli
Published 2013-09-01

Exceptionally rare IDH1-mutant adult medulloblastoma with concurrent GNAS mutation revealed by in vivo magnetic resonance spectroscopy and deep sequencing

by Roberto Liserre, Francesca Branzoli, Francesca Pagani, Magdalena Gryzik, Manuela Cominelli, Evelina Miele, Małgorzata Marjańska, Francesco Doglietto, Pietro Luigi Poliani
Published 2023-03-01

Arrangement of Live Human Cells through Acoustic Waves Generated by Piezoelectric Actuators for Tissue Engineering Applications

by Marialaura Serzanti, Marco Baù, Marco Demori, Serena Calamaio, Manuela Cominelli, Pietro Luigi Poliani, Patrizia Dell’Era, Marco Ferrari, Vittorio Ferrari
Published 2020-05-01

Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line

by Francesca Pagani, Magdalena Gryzik, Elena Somenza, Manuela Cominelli, Piera Balzarini, Alberto Schreiber, Davide Mattavelli, Piero Nicolai, Francesco Doglietto, Pietro Luigi Poliani
Published 2023-02-01

Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System

by Serena Calamaio, Marialaura Serzanti, Jennifer Boniotti, Annamaria Fra, Emirena Garrafa, Manuela Cominelli, Rosanna Verardi, Pietro Luigi Poliani, Silvia Dotti, Riccardo Villa, Giovanna Mazzoleni, Patrizia Dell’Era, Nathalie Steimberg
Published 2023-07-01

β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and <i>Twitcher</i> Mice

by Daniela Coltrini, Adwaid Manu Krishna Chandran, Mirella Belleri, Pietro L. Poliani, Manuela Cominelli, Francesca Pagani, Miriam Capra, Stefano Calza, Simona Prioni, Laura Mauri, Alessandro Prinetti, Julia K. Kofler, Maria L. Escolar, Marco Presta
Published 2022-08-01

MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.

by Fiorella Faggi, Silvia Codenotti, Pietro Luigi Poliani, Manuela Cominelli, Nicola Chiarelli, Marina Colombi, Marika Vezzoli, Eugenio Monti, Federica Bono, Giovanni Tulipano, Chiara Fiorentini, Alessandra Zanola, Harriet P Lo, Robert G Parton, Charles Keller, Alessandro Fanzani
Published 2015-01-01

Cytotoxic Effect of Progesterone, Tamoxifen and Their Combination in Experimental Cell Models of Human Adrenocortical Cancer

by Elisa Rossini, Mariangela Tamburello, Andrea Abate, Silvia Beretta, Martina Fragni, Manuela Cominelli, Deborah Cosentini, Constanze Hantel, Constanze Hantel, Federica Bono, Salvatore Grisanti, Pietro Luigi Poliani, Guido A. M. Tiberio, Maurizio Memo, Sandra Sigala, Alfredo Berruti
Published 2021-04-01

Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma.

by Fiorella Faggi, Stefania Mitola, Guglielmo Sorci, Francesca Riuzzi, Rosario Donato, Silvia Codenotti, Pietro Luigi Poliani, Manuela Cominelli, Raffaella Vescovi, Stefania Rossi, Stefano Calza, Marina Colombi, Fabio Penna, Paola Costelli, Ilaria Perini, Maurilio Sampaolesi, Eugenio Monti, Alessandro Fanzani
Published 2014-01-01

mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma

by Valentina Conti, Manuela Cominelli, Valentina Pieri, Alberto L. Gallotti, Ilaria Pagano, Matteo Zanella, Stefania Mazzoleni, Flavia Pivetta, Monica Patanè, Giulia M. Scotti, Ignazio S. Piras, Bianca Pollo, Andrea Falini, Alessio Zippo, Antonella Castellano, Roberta Maestro, Pietro L. Poliani, Rossella Galli
Published 2021-12-01

Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis

by Filippo Gagliardi, Ashwin Narayanan, Alberto Luigi Gallotti, Valentina Pieri, Stefania Mazzoleni, Manuela Cominelli, Sara Rezzola, Michela Corsini, Gianluca Brugnara, Luisa Altabella, Letterio Salvatore Politi, Marco Bacigaluppi, Andrea Falini, Antonella Castellano, Roberto Ronca, Pietro Luigi Poliani, Pietro Mortini, Rossella Galli
Published 2020-02-01

Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas

by Francesca De Bacco, Francesca Orzan, Giovanni Crisafulli, Marta Prelli, Claudio Isella, Elena Casanova, Raffaella Albano, Gigliola Reato, Jessica Erriquez, Antonio D’Ambrosio, Mara Panero, Carmine Dall’Aglio, Laura Casorzo, Manuela Cominelli, Francesca Pagani, Antonio Melcarne, Pietro Zeppa, Roberto Altieri, Isabella Morra, Paola Cassoni, Diego Garbossa, Anna Cassisa, Alice Bartolini, Serena Pellegatta, Paolo M. Comoglio, Gaetano Finocchiaro, Pietro L. Poliani, Carla Boccaccio
Published 2023-08-01