Towards an ecological definition of sepsis: a viewpoint

by Michael Bauer, Manu Shankar-Hari, Daniel O. Thomas-Rüddel, Reinhard Wetzker
Published 2021-12-01

Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

by Julie K. Wilson, Yuan Zhao, Mervyn Singer, Jo Spencer, Manu Shankar-Hari
Published 2018-04-01

The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study

by Peter J. McGuigan, Manu Shankar-Hari, David A. Harrison, John G. Laffey, Danny F. McAuley
Published 2020-06-01

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

by Shalini Santhakumaran, Anthony Gordon, A. Toby Prevost, Cecilia O’Kane, Daniel F. McAuley, Manu Shankar-Hari
Published 2019-05-01

Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis

by Vera B. M. Peters, Nishkantha Arulkumaran, Miranda J. Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Published 2022-12-01

Impact of vaccination on COVID-19-associated admissions to critical care in England: a study of population linked data with quantitative bias analysis for linkage error.

by David Harrison, Peter Watkinson, James Doidge, Manu Shankar-Hari, Paul Mouncey, Martina Patone, Carol Coupland, Julia Hippisley-Cox, Kathryn Rowan
Published 2022-08-01

Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia

by Bryan S. Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O. Harhay
Published 2023-04-01

Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release

by Hassan O. J. Morad, Suaib Luqman, Larissa Garcia Pinto, Kevin P. Cunningham, Bruno Vilar, Georgia Clayton, Manu Shankar-Hari, Peter A. McNaughton
Published 2022-06-01

Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial

by Andrew James Boyle, Peter Ferris, Ian Bradbury, John Conlon, Manu Shankar-Hari, Angela J. Rogers, Cecilia M. O’Kane, Daniel F. McAuley
Published 2022-06-01

Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

by Manu Shankar-Hari, Lise Estcourt, Heli Harvala, David Roberts, David K. Menon, On behalf of the United Kingdom SARS-CoV-2 Convalescent Plasma Evaluation (SCoPE) Consortium
Published 2020-07-01

Protocol for a scoping review of sepsis epidemiology

by M. Elizabeth Wilcox, Marietou Daou, Joanna C. Dionne, Peter Dodek, Marina Englesakis, Allan Garland, Claire Lauzon, Osama Loubani, Bram Rochwerg, Manu Shankar-Hari, Kednapa Thavorn, Andrea C. Tricco
Published 2022-06-01

Faecal microbiota transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant Organisms (FERARO): a prospective, randomised placebo-controlled feasibility trial

by Catey Bunce, Anna Goodman, Gregory Amos, Blair Merrick, Emily Robinson, Liz Allen, Karen Bisnauthsing, Chi Chi Izundu, Jordana Bell, Manu Shankar-Hari, Debbie L Shawcross, Simon D Goldenberg
Published 2020-05-01

Current Understanding of Leukocyte Phenotypic and Functional Modulation During Extracorporeal Membrane Oxygenation: A Narrative Review

by Katrina K. Ki, Katrina K. Ki, Jonathan E. Millar, Jonathan E. Millar, Jonathan E. Millar, Daman Langguth, Margaret R. Passmore, Margaret R. Passmore, Charles I. McDonald, Charles I. McDonald, Kiran Shekar, Kiran Shekar, Manu Shankar-Hari, Manu Shankar-Hari, Hwa Jin Cho, Hwa Jin Cho, Hwa Jin Cho, Jacky Y. Suen, Jacky Y. Suen, John F. Fraser, John F. Fraser
Published 2021-01-01

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y₁₂ Inhibition

by Aitana Braza-Boïls, Temo Barwari, Clemens Gutmann, Mark R. Thomas, Heather M. Judge, Abhishek Joshi, Raimund Pechlaner, Manu Shankar-Hari, Ramzi A. Ajjan, Ian Sabroe, Robert F. Storey, Manuel Mayr
Published 2020-04-01

Publisher Correction: The effect of blood pressure on mortality following out‑of‑hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National...

by Peter J. McGuigan, Elisa Giallongo, Bronagh Blackwood, James Doidge, David A. Harrison, Alistair D. Nichol, Kathryn M. Rowan, Manu Shankar‑Hari, Markus B. Skrifvars, Karen Thomas, Danny F. McAuley
Published 2023-05-01

International variation in the management of severe COVID-19 patients

by Elie Azoulay, Jan de Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar-Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi
Published 2020-08-01

The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Ce...

by Peter J. McGuigan, Elisa Giallongo, Bronagh Blackwood, James Doidge, David A. Harrison, Alistair D. Nichol, Kathryn M. Rowan, Manu Shankar-Hari, Markus B. Skrifvars, Karen Thomas, Danny F. McAuley
Published 2023-01-01

Disrupted Peyer’s Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus

by Silvia C. Trevelin, Suzanne Pickering, Katrina Todd, Cynthia Bishop, Michael Pitcher, Jose Garrido Mesa, Lucia Montorsi, Filomena Spada, Nedyalko Petrov, Anna Green, Manu Shankar-Hari, Stuart J.D. Neil, Jo Spencer
Published 2022-02-01

Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak

by Elie Azoulay, Jan De Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu, Maurizio Cecconi, ESICM
Published 2020-08-01

Towards a biological definition of ARDS: are treatable traits the solution?

by Lieuwe D. J. Bos, John G. Laffey, Lorraine B. Ware, Nanon F. L. Heijnen, Pratik Sinha, Brijesh Patel, Matthieu Jabaudon, Julie A. Bastarache, Daniel F. McAuley, Charlotte Summers, Carolyn S. Calfee, Manu Shankar-Hari
Published 2022-03-01