Kidney Allograft Function Is a Confounder of Urine Metabolite Profiles in Kidney Allograft Recipients

by Karsten Suhre, Darshana M. Dadhania, John Richard Lee, Thangamani Muthukumar, Qiuying Chen, Steven S. Gross, Manikkam Suthanthiran
Published 2021-08-01

Intervention using vitamin D for elevated urinary albumin in type 2 diabetes mellitus (IDEAL-2 Study): study protocol for a randomised controlled trial

by Shahrad Taheri, Muhammad Asim, Hassan al Malki, Omar Fituri, Manikkam Suthanthiran, Phyllis August, IDEAL-2 Study Team
Published 2018-04-01

Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract

by Philip Burnham, Darshana Dadhania, Michael Heyang, Fanny Chen, Lars F. Westblade, Manikkam Suthanthiran, John Richard Lee, Iwijn De Vlaminck
Published 2018-06-01

Gut microbiota and tacrolimus dosing in kidney transplantation.

by John R Lee, Thangamani Muthukumar, Darshana Dadhania, Ying Taur, Robert R Jenq, Nora C Toussaint, Lilan Ling, Eric Pamer, Manikkam Suthanthiran
Published 2015-01-01

474 An Investigation of Novel Urinary Cell mRNA Profiles for Noninvasive Diagnosis of Acute Rejection in Kidney Transplant Recipients

by Thalia Salinas, Carol Li, Catherine Snopkowski, Gabriel Stryjniak, Shady Albakry, Ruchuang Ding, Steven P. Salvatore, Surya V. Seshan, Darshana M. Dadhania, Thangamani Muthukumar, Manikkam Suthanthiran
Published 2024-04-01

Separating the signal from the noise in metagenomic cell-free DNA sequencing

by Philip Burnham, Nardhy Gomez-Lopez, Michael Heyang, Alexandre Pellan Cheng, Joan Sesing Lenz, Darshana M. Dadhania, John Richard Lee, Manikkam Suthanthiran, Roberto Romero, Iwijn De Vlaminck
Published 2020-02-01

A quantitative comparison of urine centrifugation and filtration for the isolation and analysis of urinary nucleic acid biomarkers

by Liz-Audrey Kounatse Djomnang, Carol Li, Omary Mzava, Alexandre Pellan Cheng, Adrienne Chang, Joan Sesing Lenz, Manikkam Suthanthiran, John R. Lee, Darshana M. Dadhania, Iwijn De Vlaminck
Published 2024-05-01

Deep sequencing of DNA from urine of kidney allograft recipients to estimate donor/recipient-specific DNA fractions.

by Aziz Belkadi, Gaurav Thareja, Darshana Dadhania, John R Lee, Thangamani Muthukumar, Catherine Snopkowski, Carol Li, Anna Halama, Sara Abdelkader, Silvana Abdulla, Yasmin Mahmoud, Joel Malek, Manikkam Suthanthiran, Karsten Suhre
Published 2021-01-01

Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts

by Bryan J. Dooley, MD, Akanksha Verma, BA, Ruchuang Ding, MD, Hua Yang, MD, Thangamani Muthukumar, MD, Michele Lubetzky, MD, Divya Shankaranarayanan, MD, Olivier Elemento, PhD, Manikkam Suthanthiran, MD
Published 2020-08-01

319 Optimizing Urinary cell mRNA profiling of kidney allograft recipients: Development of a home processing protocol for noninvasive diagnosis of T cell mediated rejection and BK v...

by Thalia Salinas, Carol Li, Catherine Snopkowski, Gabriel Stryjniak, Divya Shankaranarayanan, Shady Albakry, Ruchuang Ding, Vijay K. Sharma, Steven P. Salvatore, Surya V. Seshan, Darshana M. Dadhania, Thangamani Muthukumar, Manikkam Suthanthiran
Published 2023-04-01

Exome Sequencing and Prediction of Long-Term Kidney Allograft Function.

by Laurent Mesnard, Thangamani Muthukumar, Maren Burbach, Carol Li, Huimin Shang, Darshana Dadhania, John R Lee, Vijay K Sharma, Jenny Xiang, Caroline Suberbielle, Maryvonnick Carmagnat, Nacera Ouali, Eric Rondeau, John J Friedewald, Michael M Abecassis, Manikkam Suthanthiran, Fabien Campagne
Published 2016-09-01

A metagenomic DNA sequencing assay that is robust against environmental DNA contamination

by Omary Mzava, Alexandre Pellan Cheng, Adrienne Chang, Sami Smalling, Liz-Audrey Kounatse Djomnang, Joan Sesing Lenz, Randy Longman, Amy Steadman, Luis G. Gómez-Escobar, Edward J. Schenck, Mirella Salvatore, Michael J. Satlin, Manikkam Suthanthiran, John R. Lee, Christopher E. Mason, Darshana Dadhania, Iwijn De Vlaminck
Published 2022-07-01

Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts.

by Hemant Suryawanshi, Hua Yang, Michelle Lubetzky, Pavel Morozov, Mila Lagman, Gaurav Thareja, Alicia Alonso, Carol Li, Catherine Snopkowski, Aziz Belkadi, Franco B Mueller, John R Lee, Darshana M Dadhania, Steven P Salvatore, Surya V Seshan, Vijay K Sharma, Karsten Suhre, Manikkam Suthanthiran, Thomas Tuschl, Thangamani Muthukumar
Published 2022-01-01

Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts

by Hemant Suryawanshi, Hua Yang, Michelle Lubetzky, Pavel Morozov, Mila Lagman, Gaurav Thareja, Alicia Alonso, Carol Li, Catherine Snopkowski, Aziz Belkadi, Franco B. Mueller, John R. Lee, Darshana M. Dadhania, Steven P. Salvatore, Surya V. Seshan, Vijay K. Sharma, Karsten Suhre, Manikkam Suthanthiran, Thomas Tuschl, Thangamani Muthukumar
Published 2022-01-01

Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection

by Matthew Magruder, Adam N. Sholi, Catherine Gong, Lisa Zhang, Emmanuel Edusei, Jennifer Huang, Shady Albakry, Michael J. Satlin, Lars F. Westblade, Carl Crawford, Darshana M. Dadhania, Michelle Lubetzky, Ying Taur, Eric Littman, Lilan Ling, Philip Burnham, Iwijn De Vlaminck, Eric Pamer, Manikkam Suthanthiran, John Richard Lee
Published 2019-12-01

Design and Methods of the Validating Injury to the Renal Transplant Using Urinary Signatures (VIRTUUS) Study in Children

by Juhi Kumar, MD, MPH, Kévin Contrepois, PhD, Michael Snyder, PhD, Paul C. Grimm, MD, Asha Moudgil, MD, Jodi M. Smith, MD, Amy E. Bobrowski, MD, MS, Priya S. Verghese, MBBS, MPH, David Hooper, MD, Elizabeth Ingulli, MD, Rachel Lestz, MD, MHS, Patricia Weng, MD, Janaiya L. Reason, MPH, Tom D. Blydt-Hansen, MDCM, Manikkam Suthanthiran, MD, Brendan Keating, PhD, Sandra Amaral, MD, MHS
Published 2021-12-01

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

by Kawai, Tatsuo, Cosimi, A. Benedict, Spitzer, Thomas Richard, Tolkoff-Rubin, Nina Ellen, Suthanthiran, Manikkam, Saidman, Susan L., Shaffer, Juanita, Preffer, Frederic Ira, Ding, Ruchuang, Sharma, Vijay, Fishman, Jay Alan, Dey, Bimalangshu, Ko, Dicken S.C., Hertl, Martin, Goes, Nelson B., Wong, Waichi, Williams, Winfred Woodrow, Colvin, Robert Barnes, Sykes, Megan, Sachs, David H.
Published 2016