Highly blood perfused, highly metabolically active pancreatic islets may be more susceptible for immune attack

by Sara Ullsten, Daniel Espes, My Quach, Malin Fex, Monica Sandberg, Per‐Ola Carlsson
Published 2020-07-01

Insulin/Glucose-Responsive Cells Derived from Induced Pluripotent Stem Cells: Disease Modeling and Treatment of Diabetes

by Sevda Gheibi, Tania Singh, Joao Paulo M. C. M. da Cunha, Malin Fex, Hindrik Mulder
Published 2020-11-01

High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease

by Osama F. Elabi, João Paulo M. C. M. Cunha, Abderahim Gaceb, Malin Fex, Gesine Paul
Published 2021-08-01

The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats

by Marika Bogdani, Linda Faxius, Malin Fex, Anita Ramelius, Anya Wernersson, John P. Mordes, Elizabeth P. Blankenhorn, Åke Lernmark
Published 2021-03-01

Platelet Serotonin Levels Are Associated with Plasma Soluble Leptin Receptor Concentrations in Normoglycemic Women

by Luis Rodrigo Cataldo, José Suazo, Pablo Olmos, Carolina Bravo, José E. Galgani, Malin Fex, J. Alfredo Martínez, José L. Santos
Published 2019-01-01

Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

by Lisa M. Nicholas, Bérengère Valtat, Anya Medina, Lotta Andersson, Mia Abels, Inês G. Mollet, Deepak Jain, Lena Eliasson, Nils Wierup, Malin Fex, Hindrik Mulder
Published 2017-07-01

A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells

by Yingying Ye, Mohammad Barghouth, Haiqiang Dou, Cheng Luan, Yongzhi Wang, Alexandros Karagiannopoulos, Xiaoping Jiang, Ulrika Krus, Malin Fex, Quan Zhang, Lena Eliasson, Patrik Rorsman, Enming Zhang, Erik Renström
Published 2022-07-01

The human batokine EPDR1 regulates β-cell metabolism and function

by Luis Rodrigo Cataldo, Qian Gao, Lidia Argemi-Muntadas, Ondrej Hodek, Elaine Cowan, Sergey Hladkou, Sevda Gheibi, Peter Spégel, Rashmi B. Prasad, Lena Eliasson, Camilla Scheele, Malin Fex, Hindrik Mulder, Thomas Moritz
Published 2022-12-01

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

by Elvira Ganic, Tania Singh, Cheng Luan, João Fadista, Jenny K. Johansson, Holly Ann Cyphert, Hedvig Bennet, Petter Storm, Gaëlle Prost, Henrik Ahlenius, Erik Renström, Roland Stein, Leif Groop, Malin Fex, Isabella Artner
Published 2016-03-01

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.

by Samina Asad, Pernilla Nikamo, Alexandra Gyllenberg, Hedvig Bennet, Ola Hansson, Nils Wierup, Diabetes Incidence in Sweden Study Group, Annelie Carlsson, Gun Forsander, Sten-Anders Ivarsson, Helena Larsson, Åke Lernmark, Bengt Lindblad, Johnny Ludvigsson, Claude Marcus, Kjersti S Rønningen, Jan Nerup, Flemming Pociot, Holger Luthman, Malin Fex, Ingrid Kockum
Published 2012-01-01

Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assaysResearch...

by Alexander Lind, Eva Freyhult, Felipe de Jesus Cortez, Anita Ramelius, Rasmus Bennet, Peter V. Robinson, David Seftel, David Gebhart, Devangkumar Tandel, Marlena Maziarz, Helena Elding Larsson, Markus Lundgren, Annelie Carlsson, Anna-Lena Nilsson, Malin Fex, Carina Törn, Daniel Agardh, Cheng-ting Tsai, Åke Lernmark, Martina Persson, Gun Forsander, Johnny Ludvigsson, Ulf Samuelsson, Claude Marcus
Published 2024-06-01

EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion

by Bruno Blanchi, Marion Taurand, Claire Colace, Sofia Thomaidou, Charlotte Audeoud, Federica Fantuzzi, Toshiaki Sawatani, Sevda Gheibi, Joan Sabadell-Basallote, Fransje W.J. Boot, Thibault Chantier, Aline Piet, Charlotte Cavanihac, Marion Pilette, Adélie Balguerie, Hamza Olleik, Françoise Carlotti, Miriam Ejarque, Malin Fex, Hindrik Mulder, Miriam Cnop, Decio L. Eizirik, Ouardane Jouannot, Anne-Lise Gaffuri, Paul Czernichow, Arnaud Zaldumbide, Raphaël Scharfmann, Philippe Ravassard
Published 2023-10-01

Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

by Karl Bacos, Alexander Perfilyev, Alexandros Karagiannopoulos, Elaine Cowan, Jones K. Ofori, Ludivine Bertonnier-Brouty, Tina Rönn, Andreas Lindqvist, Cheng Luan, Sabrina Ruhrmann, Mtakai Ngara, Åsa Nilsson, Sevda Gheibi, Claire L. Lyons, Jens O. Lagerstedt, Mohammad Barghouth, Jonathan L.S. Esguerra, Petr Volkov, Malin Fex, Hindrik Mulder, Nils Wierup, Ulrika Krus, Isabella Artner, Lena Eliasson, Rashmi B. Prasad, Luis Rodrigo Cataldo, Charlotte Ling
Published 2023-02-01