Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles

by Gregson, J.M., Freitag, D.F., Surendran, P., Stitziel, N.O., Chowdhury, R., Burgess, S., Kaptoge, S., Gao, P., Staley, J.R., Willeit, P., Nielsen, S.F., Caslake, M., Trompet, S., Polfus, L.M., Kuulasmaa, K., Kontto, J., Perola, M., Blankenberg, S., Veronesi, G., Gianfagna, F., Mannisto, S., Kimura, A., Lin, H.H., Reilly, D.F., Gorski, M., Mijatovic, V., Munroe, P.B., Ehret, G.B., Thompson, A., Uria-Nickelsen, M., Malarstig, A., Dehghan, A., Vogt, T.F., Sasaoka, T., Takeuchi, F., Kato, N., Yamada, Y., Kee, F., Muller-Nurasyid, M., Ferrieres, J., Arveiler, D., Amouyel, P., Salomaa, V., Boerwinkle, E., Thompson, S.G., Ford, I., Jukema, J.W., Sattar, N., Packard, C.J., Majumder, A.A., Alam, D.S., Deloukas, P., Schunkert, H., Samani, N.J., Kathiresan, S., Nordestgaard, B.G., Saleheen, D., Howson, J.M.M., Angelantonio, E. di, Butterworth, A.S., Danesh, J., CKDGen Consortium, Int Consortium Blood Pressure, CHARGE Inflammation Working Grp, MICAD Exome Consortium, EPIC-CVD Consortium, CHD Exome Consortium
Published 2017

Genetic invalidation of Lp-PLA$_{2}$ as a therapeutic target: Large-scale study of five functional Lp-PLA$_{2}$-lowering alleles

by Gregson, JM, Freitag, DF, Surendran, P, Stitziel, NO, Chowdhury, R, Burgess, S, Kaptoge, S, Gao, P, Staley, JR, Willeit, P, Nielsen, SF, Caslake, M, Trompet, S, Polfus, LM, Kuulasmaa, K, Kontto, J, Perola, M, Blankenberg, S, Veronesi, G, Gianfagna, F, Männistö, S, Kimura, A, Lin, H, Reilly, DF, Gorski, M, Mijatovic, V, CKDGen consortium, Munroe, PB, Ehret, GB, International Consortium for Blood Pressure, Thompson, A, Uria-Nickelsen, M, Malarstig, A, Dehghan, A, CHARGE inflammation working group, Vogt, TF, Sasaoka, T, Takeuchi, F, Kato, N, Yamada, Y, Kee, F, Müller-Nurasyid, M, Ferrières, J, Arveiler, D, Amouyel, P, Salomaa, V, Boerwinkle, E, Thompson, SG, Ford, I, Wouter Jukema, J, Sattar, N, Packard, CJ, Shafi Majumder, AA, Alam, DS, Deloukas, P, Schunkert, H, Samani, NJ, Kathiresan, S, MICAD Exome consortium, Nordestgaard, BG, Saleheen, D, Howson, JM, Di Angelantonio, E, Butterworth, AS, Danesh, J, EPIC-CVD consortium and the CHD Exome+ consortium
Published 2017