Glutamate Carrier Involvement in Mitochondrial Dysfunctioning in the Brain White Matter

by Anne E. J. Hillen, Vivi M. Heine, Vivi M. Heine
Published 2020-07-01

Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity

by Stephanie D. Hoekstra, Sven Stringer, Vivi M. Heine, Vivi M. Heine, Danielle Posthuma, Danielle Posthuma
Published 2017-06-01

Simplified 3D protocol capable of generating early cortical neuroepithelium

by Dwayne B. Holmes, Vivi M. Heine
Published 2017-03-01

Engineered cell culture microenvironments for mechanobiology studies of brain neural cells

by Lucía Castillo Ransanz, Pieter F. J. Van Altena, Vivi M. Heine, Vivi M. Heine, Angelo Accardo
Published 2022-12-01

Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation

by Mouhamed Alsaqati, Vivi M. Heine, Adrian J. Harwood
Published 2020-10-01

KCC2 expression levels are reduced in post mortem brain tissue of Rett syndrome patients

by Lisa Hinz, Joan Torrella Barrufet, Vivi M. Heine
Published 2019-12-01

Neuron–Glia Interactions in Tuberous Sclerosis Complex Affect the Synaptic Balance in 2D and Organoid Cultures

by Stephanie Dooves, Arianne J. H. van Velthoven, Linda G. Suciati, Vivi M. Heine
Published 2021-01-01

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

by Suzy Varderidou-Minasian, Lisa Hinz, Dominique Hagemans, Danielle Posthuma, Maarten Altelaar, Vivi M. Heine
Published 2020-05-01

Comparative gene expression study and pathway analysis of the human iris- and the retinal pigment epithelium.

by Anna Bennis, Jacoline B Ten Brink, Perry D Moerland, Vivi M Heine, Arthur A Bergen
Published 2017-01-01

Patterning factors during neural progenitor induction determine regional identity and differentiation potential in vitro

by Aishwarya G. Nadadhur, Prisca S. Leferink, Dwayne Holmes, Lisa Hinz, Paulien Cornelissen-Steijger, Lisa Gasparotto, Vivi M. Heine
Published 2018-10-01

A 3D human co-culture to model neuron-astrocyte interactions in tauopathies

by Kevin L. Batenburg, Claudia Sestito, Paulien Cornelissen-Steijger, Jan R. T. van Weering, Leo S. Price, Vivi M. Heine, Wiep Scheper
Published 2023-02-01

Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons

by Javier Emperador Melero, Aishwarya G. Nadadhur, Desiree Schut, Jan V. Weering, Vivi M. Heine, Ruud F. Toonen, Matthijs Verhage
Published 2017-03-01

Cerebellar abnormalities following hypoxia alone compared to hypoxic–ischemic forebrain injury in the developing rat brain

by Valerie Biran, Vivi M. Heine, Catherine Verney, R. Ann Sheldon, Ruggero Spadafora, Zinaida S. Vexler, David H. Rowitch, Donna M. Ferriero
Published 2011-01-01

In vivo targeting of a variant causing vanishing white matter using CRISPR/Cas9

by Anne E.J. Hillen, Martina Hruzova, Tanja Rothgangl, Marjolein Breur, Marianna Bugiani, Marjo S. van der Knaap, Gerald Schwank, Vivi M. Heine
Published 2022-06-01

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models

by Aishwarya G. Nadadhur, Mouhamed Alsaqati, Lisa Gasparotto, Paulien Cornelissen-Steijger, Eline van Hugte, Stephanie Dooves, Adrian J. Harwood, Vivi M. Heine
Published 2019-01-01

In Vitro Modelling of Osteogenesis Imperfecta with Patient-Derived Induced Mesenchymal Stem Cells

by Lauria Claeys, Lidiia Zhytnik, Laura Ventura, Lisanne E. Wisse, Elisabeth M. W. Eekhoff, Gerard Pals, Nathalie Bravenboer, Vivi M. Heine, Dimitra Micha
Published 2024-03-01

Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter

by Stephanie Dooves, Prisca S. Leferink, Sander Krabbenborg, Nicole Breeuwsma, Saskia Bots, Anne E.J. Hillen, Gerbren Jacobs, Marjo S. van der Knaap, Vivi M. Heine
Published 2019-03-01

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

by Anna Bennis, Theo G M F Gorgels, Jacoline B Ten Brink, Peter J van der Spek, Koen Bossers, Vivi M Heine, Arthur A Bergen
Published 2015-01-01

Systematic assessment of variability in the proteome of iPSC derivatives

by Stephanie D. Beekhuis-Hoekstra, Kyoko Watanabe, Josefin Werme, Christiaan A. de Leeuw, Iryna Paliukhovich, Ka Wan Li, Frank Koopmans, August B. Smit, Danielle Posthuma, Vivi M. Heine
Published 2021-10-01

Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain

by Josse A. Depla, Marina Sogorb-Gonzalez, Lance A. Mulder, Vivi M. Heine, Pavlina Konstantinova, Sander J. van Deventer, Katja C. Wolthers, Dasja Pajkrt, Adithya Sridhar, Melvin M. Evers
Published 2020-09-01