Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery

by Luping Pang, Stephen D. Weeks, Arthur Van Aerschot
Published 2021-02-01

Cdc2-like kinases: structure, biological function, and therapeutic targets for diseases

by Mengqiu Song, Luping Pang, Mengmeng Zhang, Yingzi Qu, Kyle Vaughn Laster, Zigang Dong
Published 2023-04-01

Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies

by Luping Pang, Stephen D. Weeks, Martin Juhás, Sergei V. Strelkov, Jan Zitko, Arthur Van Aerschot
Published 2021-07-01

Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip

by Luping Pang, Vladimir Zanki, Sergei V. Strelkov, Arthur Van Aerschot, Ita Gruic-Sovulj, Stephen D. Weeks
Published 2022-08-01

Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases

by Manesh Nautiyal, Bharat Gadakh, Steff De Graef, Luping Pang, Masroor Khan, Yi Xun, Jef Rozenski, Arthur Van Aerschot
Published 2019-10-01

Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides

by Luping Pang, Stijn Lenders, Evgenii M. Osipov, Stephen D. Weeks, Jef Rozenski, Tatiana Piller, Davie Cappoen, Sergei V. Strelkov, Arthur Van Aerschot
Published 2022-12-01

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

by Baole Zhang, Luping Pang, Manesh Nautiyal, Steff De Graef, Bharat Gadakh, Eveline Lescrinier, Jef Rozenski, Sergei V. Strelkov, Stephen D. Weeks, Arthur Van Aerschot
Published 2020-10-01

Detailed resume of RNA m6A demethylases

by Dandan Shen, Bo Wang, Ya Gao, Lijuan Zhao, Yaping Bi, Jinge Zhang, Ning Wang, Huiqin Kang, Jingru Pang, Ying Liu, Luping Pang, Zhe-Sheng Chen, Yi-Chao Zheng, Hong-Min Liu
Published 2022-05-01