Clinical Candidates Targeting the ATR–CHK1–WEE1 Axis in Cancer

by Lukas Gorecki, Martin Andrs, Jan Korabecny
Published 2021-02-01

Profiling donepezil template into multipotent hybrids with antioxidant properties

by Eva Mezeiova, Katarina Spilovska, Eugenie Nepovimova, Lukas Gorecki, Ondrej Soukup, Rafael Dolezal, David Malinak, Jana Janockova, Daniel Jun, Kamil Kuca, Jan Korabecny
Published 2018-01-01

Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

by Marketa Chvojkova, David Kolar, Katarina Kovacova, Lada Cejkova, Anna Misiachna, Kristina Hakenova, Lukas Gorecki, Martin Horak, Jan Korabecny, Ondrej Soukup, Karel Vales
Published 2024-07-01

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer’s Disease Treatment

by Jan Korabecny, Martin Andrs, Eugenie Nepovimova, Rafael Dolezal, Katerina Babkova, Anna Horova, David Malinak, Eva Mezeiova, Lukas Gorecki, Vendula Sepsova, Martina Hrabinova, Ondrej Soukup, Daniel Jun, Kamil Kuca
Published 2015-12-01

Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

by David Malinak, Rafael Dolezal, Vendula Hepnarova, Miroslava Hozova, Rudolf Andrys, Petr Bzonek, Veronika Racakova, Jan Korabecny, Lukas Gorecki, Eva Mezeiova, Miroslav Psotka, Daniel Jun, Kamil Kuca, Kamil Musilek
Published 2020-01-01