A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.

by Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, PCAWG Tumor Subtypes and Clinical Translation Working Group, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P, Steeghs, Neeltje, Getz, Gad, Morris, Quaid, Stein, Lincoln D, PCAWG Consortium
Published 2020

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact.

by van Dessel, Lisanne F, van Riet, Job, Smits, Minke, Zhu, Yanyun, Hamberg, Paul, van der Heijden, Michiel S, Bergman, Andries M, van Oort, Inge M, de Wit, Ronald, Voest, Emile E, Steeghs, Neeltje, Yamaguchi, Takafumi N, Livingstone, Julie, Boutros, Paul C, Martens, John WM, Sleijfer, Stefan, Cuppen, Edwin, Zwart, Wilbert, van de Werken, Harmen JG, Mehra, Niven, Lolkema, Martijn P
Published 2019

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.

by Jacobetz, Michael A, Chan, Derek S, Neesse, Albrecht, Bapiro, Tashinga E, Cook, Natalie, Frese, Kristopher K, Feig, Christine, Nakagawa, Tomoaki, Caldwell, Meredith E, Zecchini, Heather I, Lolkema, Martijn P, Jiang, Ping, Kultti, Anne, Thompson, Curtis B, Maneval, Daniel C, Jodrell, Duncan I, Frost, Gregory I, Shepard, HM, Skepper, Jeremy N, Tuveson, David A
Published 2020

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

by Jiao, Wei, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Morris, Quaid, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Kaiser, Vera B., Karlić, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N., Margolin, Adam, Martin, Sancha, Nahal-Bose, Hardeep K., Nielsen, G. Petur, Nik-Zainal, Serena, Omberg, Larsson, P’ng, Christine, Perry, Marc D., Polak, Paz, Rheinbay, Esther, Rubin, Mark A., Semple, Colin A., Sgroi, Dennis C., Shibata, Tatsuhiro, Siebert, Reiner, Smith, Jaclyn, Stein, Lincoln D., Stobbe, Miranda D., Sun, Ren X., Thai, Kevin, Wright, Derek W., Wu, Chin-Lee, Yuan, Ke, Zhang, Junjun
Published 2021

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study

by Weeber, Fleur (author), Cirkel, Geert A. (author), Hoogstraat, Marlous (author), Bins, Sander (author), Gadellaa-van Hooijdonk, Christa G.M. (author), Ooft, Salo (author), van Werkhoven, Erik (author), Willems, Stefan M. (author), van Stralen, Marijn (author), Veldhuis, Wouter B. (author), Besselink, Nicolle J.M. (author), Horlings, Hugo M. (author), Steeghs, Neeltje (author), de Jonge, Maja J. (author), Langenberg, Marlies H.G. (author), Wessels, L.F.A. (author), Cuppen, Edwin (author), Cuppen, Edwin (author), Schellens, J.H. (author), Sleijfer, Stefan (author), Lolkema, Martijn P. (author), Voest, Emile E. (author)
Published 2017