Butyrate Protects Barrier Integrity and Suppresses Immune Activation in a Caco-2/PBMC Co-Culture Model While HDAC Inhibition Mimics Butyrate in Restoring Cytokine-Induced Barrier D...

by Sandra G. P. J. Korsten, Herman Vromans, Johan Garssen, Linette E. M. Willemsen
Published 2023-06-01

Allergy Modulation by N-3 Long Chain Polyunsaturated Fatty Acids and Fat Soluble Nutrients of the Mediterranean Diet

by Astrid Hogenkamp, Anna Ehlers, Anna Ehlers, Johan Garssen, Johan Garssen, Linette E. M. Willemsen
Published 2020-08-01

Specific Human Milk Oligosaccharides Differentially Promote Th1 and Regulatory Responses in a CpG-Activated Epithelial/Immune Cell Coculture

by Marit Zuurveld, Veronica Ayechu-Muruzabal, Gert Folkerts, Johan Garssen, Belinda van‘t Land, Linette E. M. Willemsen
Published 2023-01-01

Specific Polyunsaturated Fatty Acids Can Modulate in vitro Human moDC2s and Subsequent Th2 Cytokine Release

by Tamara Hoppenbrouwers, Vincenzo Fogliano, Johan Garssen, Johan Garssen, Nicoletta Pellegrini, Linette E. M. Willemsen, Harry J. Wichers
Published 2020-05-01

Long Chain Polyunsaturated Fatty Acids (LCPUFAs) in the Prevention of Food Allergy

by Tamara Hoppenbrouwers, Jelena H. Cvejić Hogervorst, Johan Garssen, Johan Garssen, Harry J. Wichers, Linette E. M. Willemsen
Published 2019-05-01

Human Milk Oligosaccharide 2′-Fucosyllactose Modulates Local Viral Immune Defense by Supporting the Regulatory Functions of Intestinal Epithelial and Immune Cells

by Veronica Ayechu-Muruzabal, Bente Poelmann, Alinda J. Berends, Nienke Kettelarij, Johan Garssen, Belinda van’t Land, Linette E. M. Willemsen
Published 2022-09-01

Dietary Fibers: Effects, Underlying Mechanisms and Possible Role in Allergic Asthma Management

by Roos E. M. Verstegen, Atanaska I. Kostadinova, Zenebech Merenciana, Johan Garssen, Gert Folkerts, Rudi W. Hendriks, Linette E. M. Willemsen
Published 2021-11-01

Exposure of Intestinal Epithelial Cells to 2′-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development

by Veronica Ayechu-Muruzabal, Saskia A. Overbeek, Atanaska I. Kostadinova, Bernd Stahl, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen
Published 2020-05-01

Fructo-Oligosaccharides Modify Human DC Maturation and Peanut-Induced Autologous T-Cell Response of Allergic Patients In Vitro

by Simone M. Hayen, Simone M. Hayen, André C. Knulst, Johan Garssen, Johan Garssen, Henny G. Otten, Linette E. M. Willemsen
Published 2021-02-01

Oral pretreatment with β-lactoglobulin derived peptide and CpG co-encapsulated in PLGA nanoparticles prior to sensitizations attenuates cow’s milk allergy development in mice

by Mengshan Liu, Mengshan Liu, Suzan Thijssen, Wim E. Hennink, Johan Garssen, Johan Garssen, Cornelus F. van Nostrum, Linette E. M. Willemsen
Published 2023-01-01

Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose a...

by Marit Zuurveld, Pien C.J. Kiliaan, Sophie E.L. van Grinsven, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen
Published 2022-10-01

Live Cell Imaging by Förster Resonance Energy Transfer Fluorescence to Study Trafficking of PLGA Nanoparticles and the Release of a Loaded Peptide in Dendritic Cells

by Mengshan Liu, Chun Yin Jerry Lau, Irene Trillo Cabello, Johan Garssen, Linette E. M. Willemsen, Wim E. Hennink, Cornelus F. van Nostrum
Published 2023-05-01

An advanced in vitro human mucosal immune model to predict food sensitizing allergenicity risk: A proof of concept using ovalbumin as model allergen

by Marit Zuurveld, Cristina Bueno Díaz, Frank Redegeld, Gert Folkerts, Johan Garssen, Johan Garssen, Belinda van’t Land, Belinda van’t Land, Linette E.M. Willemsen
Published 2023-01-01

Butyrate Prevents Induction of CXCL10 and Non-Canonical IRF9 Expression by Activated Human Intestinal Epithelial Cells via HDAC Inhibition

by Sandra G. P. J. Korsten, Laura Peracic, Luka M. B. van Groeningen, Mara A. P. Diks, Herman Vromans, Johan Garssen, Linette E. M. Willemsen
Published 2022-04-01

Diversity of Human Milk Oligosaccharides and Effects on Early Life Immune Development

by Veronica Ayechu-Muruzabal, Arthur H. van Stigt, Marko Mank, Linette E. M. Willemsen, Bernd Stahl, Johan Garssen, Johan Garssen, Belinda van't Land, Belinda van't Land
Published 2018-09-01

Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3′Galactosyllactose

by Veronica Ayechu-Muruzabal, Melanie van de Kaa, Reshmi Mukherjee, Johan Garssen, Bernd Stahl, Roland J. Pieters, Belinda van’t Land, Aletta D. Kraneveld, Linette E. M. Willemsen
Published 2022-02-01

Combined Exposure of Activated Intestinal Epithelial Cells to Nondigestible Oligosaccharides and CpG-ODN Suppresses Th2-Associated CCL22 Release While Enhancing Galectin-9, TGFβ, a...

by Saskia A. Overbeek, Atanaska I. Kostadinova, Martine A. Boks, Simone M. Hayen, Wilco de Jager, Belinda van’t land, Leon M. Knippels, Johan Garssen, Linette E. M. Willemsen
Published 2019-01-01

A Fermented Milk Matrix Containing Postbiotics Supports Th1- and Th17-Type Immunity In Vitro and Modulates the Influenza-Specific Vaccination Response In Vivo in Association with A...

by Veronica Ayechu-Muruzabal, Ling Xiao, Tjalling Wehkamp, Ingrid van Ark, Elisabeth J. Hoogendoorn, Thea Leusink-Muis, Gert Folkerts, Johan Garssen, Linette E. M. Willemsen, Belinda van’t Land
Published 2021-03-01

Immunomodulation by Human Milk Oligosaccharides: The Potential Role in Prevention of Allergic Diseases

by Marit Zuurveld, Nikita P. van Witzenburg, Johan Garssen, Johan Garssen, Gert Folkerts, Bernd Stahl, Bernd Stahl, Bernd Stahl, Belinda van't Land, Belinda van't Land, Linette E. M. Willemsen
Published 2020-05-01

Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2’-fucosyllactose and short-chain galacto- and long-chain fructo-oligosacch...

by Veronica Ayechu-Muruzabal, Merel de Boer, Bart Blokhuis, Alinda J. Berends, Johan Garssen, Johan Garssen, Aletta D. Kraneveld, Belinda van’t Land, Belinda van’t Land, Linette E. M. Willemsen
Published 2022-12-01