Genetics of Type 2 Diabetes: Past, Present, and Future

by Markku Laakso, Lilian Fernandes Silva
Published 2022-08-01

The “Common Soil Hypothesis” Revisited—Risk Factors for Type 2 Diabetes and Cardiovascular Disease

by Lilian Fernandes Silva, Jagadish Vangipurapu, Markku Laakso
Published 2021-10-01

Statins and risk of type 2 diabetes: mechanism and clinical implications

by Markku Laakso, Markku Laakso, Lilian Fernandes Silva
Published 2023-09-01

Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways

by Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Markku Laakso
Published 2022-08-01

Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease

by Lilian Fernandes Silva, Jagadish Vangipurapu, Anniina Oravilahti, Ville Männistö, Markku Laakso
Published 2023-02-01

Effects of <i>SLCO1B1</i> Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

by Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Anniina Oravilahti, Markku Laakso
Published 2022-11-01

Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men

by Susanna Maria Kemppainen, Lilian Fernandes Silva, Maria Anneli Lankinen, Ursula Schwab, Markku Laakso
Published 2022-01-01

Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study

by Rowmika Ravi, Lilian Fernandes Silva, Jagadish Vangipurapu, Maleeha Maria, Joose Raivo, Seppo Helisalmi, Markku Laakso
Published 2022-05-01

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp—A Study in Finns

by Eleni Rebelos, Miikka-Juhani Honka, Laura Ekblad, Marco Bucci, Jarna C. Hannukainen, Lilian Fernandes Silva, Kirsi A. Virtanen, Lauri Nummenmaa, Pirjo Nuutila
Published 2021-03-01

Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort

by Sahereh Mirzaei, Holli A. DeVon, Rita M. Cantor, Arjen J. Cupido, Calvin Pan, Sung Min Ha, Lilian Fernandes Silva, James R. Hilser, Jaana Hartiala, Hooman Allayee, Federico E. Rey, Markku Laakso, Aldons J. Lusis
Published 2024-03-01

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

by Xianyong Yin, Lap Sum Chan, Debraj Bose, Anne U. Jackson, Peter VandeHaar, Adam E. Locke, Christian Fuchsberger, Heather M. Stringham, Ryan Welch, Ketian Yu, Lilian Fernandes Silva, Susan K. Service, Daiwei Zhang, Emily C. Hector, Erica Young, Liron Ganel, Indraniel Das, Haley Abel, Michael R. Erdos, Lori L. Bonnycastle, Johanna Kuusisto, Nathan O. Stitziel, Ira M. Hall, Gregory R. Wagner, FinnGen, Jian Kang, Jean Morrison, Charles F. Burant, Francis S. Collins, Samuli Ripatti, Aarno Palotie, Nelson B. Freimer, Karen L. Mohlke, Laura J. Scott, Xiaoquan Wen, Eric B. Fauman, Markku Laakso, Michael Boehnke
Published 2022-03-01