Tumor Microenvironment and Metabolism

by Li V. Yang
Published 2017-12-01

Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells

by Lixue Dong, Elizabeth A. Krewson, Li V. Yang
Published 2017-01-01

Acidic Tumor Microenvironment and pH-Sensing G protein-Coupled Receptors

by Calvin R. Justus, Lixue eDong, Li V. Yang
Published 2013-12-01

Complex Role of Microbiome in Pancreatic Tumorigenesis: Potential Therapeutic Implications

by Suneetha Amara, Li V. Yang, Venkataswarup Tiriveedhi, Mahvish Muzaffar
Published 2022-06-01

Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment

by Calvin R. Justus, Edward J. Sanderlin, Li V. Yang
Published 2015-05-01

Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8

by Zhigang Li, Lixue Dong, Eric Dean, Li V. Yang
Published 2013-10-01

Can GPR4 Be a Potential Therapeutic Target for COVID-19?

by Li V. Yang, Li V. Yang, Karen A. Oppelt, Mary Jane Thomassen, Mona A. Marie, Shayan Nik Akhtar, Justin D. McCallen
Published 2021-01-01

Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis.

by Lixue Dong, Zhigang Li, Nancy R Leffler, Adam S Asch, Jen-Tsan Chi, Li V Yang
Published 2013-01-01

Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway.

by Aishe Chen, Lixue Dong, Nancy R Leffler, Adam S Asch, Owen N Witte, Li V Yang
Published 2011-01-01

Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies

by Calvin R. Justus, Edward J. Sanderlin, Lixue Dong, Tianai Sun, Jen-Tsan Chi, Kvin Lertpiriyapong, Li V. Yang
Published 2017-10-01

The Proton-Sensing GPR4 Receptor Regulates Paracellular Gap Formation and Permeability of Vascular Endothelial Cells

by Elizabeth A. Krewson, Edward J. Sanderlin, Mona A. Marie, Shayan Nik Akhtar, Juraj Velcicky, Pius Loetscher, Li V. Yang
Published 2020-02-01

Quantitative analysis and comparison of 3D morphology between viable and apoptotic MCF-7 breast cancer cells and characterization of nuclear fragmentation.

by Yuhua Wen, Zhan Chen, Jianfen Lu, Elizabeth Ables, Jean-Luc Scemama, Li V Yang, Jun Q Lu, Xin-Hua Hu
Published 2017-01-01

GPR4 Knockout Attenuates Intestinal Inflammation and Forestalls the Development of Colitis-Associated Colorectal Cancer in Murine Models

by Mona A. Marie, Edward J. Sanderlin, Alexander P. Hoffman, Kylie D. Cashwell, Swati Satturwar, Heng Hong, Ying Sun, Li V. Yang
Published 2023-10-01

Isolated neutropenia as a rare but serious adverse event secondary to immune checkpoint inhibition

by Abdul Rafeh Naqash, Ebenezer Appah, Li V. Yang, Mahvish Muzaffar, Mona A. Marie, Justin D. Mccallen, Shravanti Macherla, Darla Liles, Paul R. Walker
Published 2019-07-01

Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression

by James A. McCubrey, Li V. Yang, Stephen L. Abrams, Linda S. Steelman, Matilde Y. Follo, Lucio Cocco, Stefano Ratti, Alberto M. Martelli, Giuseppa Augello, Melchiorre Cervello
Published 2022-07-01

Case Report: Peripheral blood T cells and inflammatory molecules in lung cancer patients with immune checkpoint inhibitor-induced thyroid dysfunction: Case studies and literature r...

by Mona A. Marie, Justin D. McCallen, Zahra S. Hamedi, Abdul Rafeh Naqash, Abdul Rafeh Naqash, Alexander Hoffman, Druid Atwell, Suneetha Amara, Mahvish Muzaffar, Paul R. Walker, Paul R. Walker, Li V. Yang
Published 2022-12-01

Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune c...

by Kun Wang, Sanna Iivanainen, Jussi Pekka Koivunen, Abdul Rafeh Naqash, Mahvish Muzaffar, Shravanti Macherla, James Clark, Joo Sang Lee, Eytan Ruppin, David J Pinato, Emma Mi, Daria Gramenitskaya, Sweta Jonnalagadda, Shanker Polsani, Paul R Walker, Justin D McCallen, Mona A Marie, Rahim Ali Jiwani, Maida Hafiz, Leonardo Brunetti, Chipman R G Stroud, Youngmin Chung, Li V Yang
Published 2023-10-01