A multicellular brain spheroid model for studying the mechanisms and bioeffects of ultrasound-enhanced drug penetration beyond the blood‒brain barrier

by Anurag N. Paranjape, Leonardo D’Aiuto, Wenxiao Zheng, Xucai Chen, Flordeliza S. Villanueva
Published 2024-01-01

Dissection of structure and function of the N-terminal domain of mouse DNMT1 using regional frame-shift mutagenesis.

by Leonardo D'Aiuto, Marco Marzulli, K Naga Mohan, Ewa Borowczyk, Federica Saporiti, Andrew Vandemark, J Richard Chaillet
Published 2010-03-01

Insights into bioinformatic approaches for repurposing compounds as anti-viral drugs

by Wenxiao Zheng, Leonardo D’Aiuto, Matthew J Demers, Vaishali Muralidaran, Joel A Wood, Maribeth Wesesky, Ansuman Chattopadhyay, Vishwajit L Nimgaonkar
Published 2021-08-01

Asymmetric Entry into 10b‑aza-Analogues of Amaryllidaceae Alkaloids Reveals a Pronounced Electronic Effect on Antiviral Activity

by Carla E. Brown, Tiffany Kong, James F. Britten, Nick H. Werstiuk, James McNulty, Leonardo D’Aiuto, Matthew Demers, Vishwajit L. Nimgaonkar
Published 2018-09-01

The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids

by Leonardo D’Aiuto, Jill K. Caldwell, Callen T. Wallace, Tristan R. Grams, Maribeth A. Wesesky, Joel A. Wood, Simon C. Watkins, Paul R. Kinchington, David C. Bloom, Vishwajit L. Nimgaonkar
Published 2022-11-01

Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

by James McNulty, Chanti Babu-Dokuburra, Jon Scattolon, Carlos Zepeda-Velazquez, Maribeth A. Wesesky, Jill K. Caldwell, Wenxiao Zheng, Jadranka Milosevic, Paul R. Kinchington, David C. Bloom, Vishwajit L. Nimgaonkar, Leonardo D’Aiuto
Published 2023-01-01

Correction: Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural Cells.

by Leonardo D'Aiuto, Roberto Di Maio, Brianna Heath, Giorgio Raimondi, Jadranka Milosevic, Annie M. Watson, Mikhil Bamne, W. Tony Parks, Lei Yang, Bo Lin, Toshio Miki, Jocelyn Danielle Mich-Basso, Ravit Arav-Boger, Etienne Sibille, Sarven Sabunciyan, Robert Yolken, Vishwajit Nimgaonkar
Published 2014-01-01

Human induced pluripotent stem cell-derived models to investigate human cytomegalovirus infection in neural cells.

by Leonardo D'Aiuto, Roberto Di Maio, Brianna Heath, Giorgio Raimondi, Jadranka Milosevic, Annie M Watson, Mikhil Bamne, W Tony Parks, Lei Yang, Bo Lin, Toshio Miki, Jocelyn Danielle Mich-Basso, Ravit Arav-Boger, Etienne Sibille, Sarven Sabunciyan, Robert Yolken, Vishwajit Nimgaonkar
Published 2012-01-01

Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections

by Leonardo D’Aiuto, Jennifer Naciri, Nicholas Radio, Sesha Tekur, Dennis Clayton, Gerard Apodaca, Roberto Di Maio, Yun Zhi, Peter Dimitrion, Paolo Piazza, Matthew Demers, Joel Wood, Charleen Chu, Jason Callio, Lora McClain, Robert Yolken, James McNulty, Paul Kinchington, David Bloom, Vishwajit Nimgaonkar
Published 2018-05-01

The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Infl...

by Morganna C. Lima, Leila R. de Mendonça, Antonio M. Rezende, Raquel M. Carrera, Conceição E. Aníbal-Silva, Matthew Demers, Leonardo D'Aiuto, Joel Wood, Kodavali V. Chowdari, Michael Griffiths, Antonio R. Lucena-Araujo, Manoel Barral-Netto, Elisa A. N. Azevedo, Renan W. Alves, Pablo C. S. Farias, Ernesto T. A. Marques, Ernesto T. A. Marques, Priscila M. S. Castanha, Claire L. Donald, Alain Kohl, Vishwajit L. Nimgaonkar, Vishwajit L. Nimgaonkar, Rafael F. O. Franca
Published 2019-08-01