Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine

by Patricia Gogesch, Inessa Penner, Steffi Krauter, Nicole Büscher, Leander Grode, Inci Aydin, Bodo Plachter
Published 2019-09-01

The Recombinant Bacille Calmette–Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing

by Natalie E. Nieuwenhuizen, Prasad S. Kulkarni, Umesh Shaligram, Mark F. Cotton, Cyrill A. Rentsch, Cyrill A. Rentsch, Bernd Eisele, Leander Grode, Stefan H. E. Kaufmann
Published 2017-09-01

Safety and Immunogenicity of Recombinant <i>Bacille Calmette-Guérin</i> Strain VPM1002 and Its Derivatives in a Goat Model

by Julia Figl, Heike Köhler, Nadine Wedlich, Elisabeth M. Liebler-Tenorio, Leander Grode, Gerald Parzmair, Gopinath Krishnamoorthy, Natalie E. Nieuwenhuizen, Stefan H. E. Kaufmann, Christian Menge
Published 2023-03-01

Vaccine-Induced Subcutaneous Granulomas in Goats Reflect Differences in Host–Mycobacterium Interactions between BCG- and Recombinant BCG-Derivative Vaccines

by Elisabeth M. Liebler-Tenorio, Johannes Heyl, Nadine Wedlich, Julia Figl, Heike Köhler, Gopinath Krishnamoorthy, Natalie E. Nieuwenhuizen, Leander Grode, Stefan H. E. Kaufmann, Christian Menge
Published 2022-09-01

Nonclinical Development of BCG Replacement Vaccine Candidates

by Bernd Eisele, Martin Gengenbacher, Reginald Kidd, David McCown, Sheldon Morris, Steven Derrick, David Hokey, Dominick Laddy, Rosemary Chang, Megan Fitzpatrick, Leander Grode, Kamalakannan Velmurugan, Stefan H.E. Kaufmann, John Fulkerson, Michael J. Brennan
Published 2013-04-01

Video Endoscopy-Guided Intrabronchial Spray Inoculation of Mycobacterium bovis in Goats and Comparative Assessment of Lung Lesions With Various Imaging Methods

by Nadine Wedlich, Julia Figl, Elisabeth M. Liebler-Tenorio, Heike Köhler, Kerstin von Pückler, Melanie Rissmann, Stefanie Petow, Stefanie A. Barth, Petra Reinhold, Reiner Ulrich, Leander Grode, Stefan H. E. Kaufmann, Stefan H. E. Kaufmann, Stefan H. E. Kaufmann, Christian Menge
Published 2022-05-01

Results of the phase I open label clinical trial SAKK 06/14 assessing safety of intravesical instillation of VPM1002BC, a recombinant mycobacterium Bacillus Calmette Guérin (BCG),...

by Cyrill A. Rentsch, Piet Bosshard, Grégoire Mayor, Malte Rieken, Heike Püschel, Grégory Wirth, Richard Cathomas, Gerald P. Parzmair, Leander Grode, Bernd Eisele, Hitt Sharma, Manish Gupta, Sunil Gairola, Umesh Shaligram, Daniel Goldenberger, François Spertini, Régine Audran, Milica Enoiu, Simona Berardi, Stefanie Hayoz, Andreas Wicki
Published 2020-01-01