Updates in Anthracycline-Mediated Cardiotoxicity

by Canan G. Nebigil, Laurent Désaubry
Published 2018-11-01

Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

by Dong Wang, Xinyue Ma, Linru Dong, Hairong Feng, Peng Yu, Laurent Désaubry, Laurent Désaubry
Published 2019-11-01

Novel carbocationic rearrangements of 1-styrylpropargyl alcohols

by Christine Basmadjian, Fan Zhang, Laurent Désaubry
Published 2015-06-01

Targeting GPCRs Against Cardiotoxicity Induced by Anticancer Treatments

by Anais Audebrand, Laurent Désaubry, Canan G. Nebigil
Published 2020-01-01

The flavagline FL3 interferes with the association of Annexin A2 with the eIF4F initiation complex and transiently stimulates the translation of annexin A2 mRNA

by Ann Kari Grindheim, Sudarshan S. Patil, Canan G. Nebigil, Laurent Désaubry, Anni Vedeler
Published 2023-05-01

Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies

by Po-Yen Hsu, Aynura Mammadova, Nadia Benkirane-Jessel, Laurent Désaubry, Canan G. Nebigil
Published 2021-07-01

Targeting Prohibitins to Inhibit Melanoma Growth and Overcome Resistance to Targeted Therapies

by Ahmad Najem, Mohammad Krayem, Serena Sabbah, Matilde Pesetti, Fabrice Journe, Ahmad Awada, Laurent Désaubry, Ghanem E. Ghanem
Published 2023-07-01

Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27.

by Yohann Bernard, Nigel Ribeiro, Frédéric Thuaud, Gülen Türkeri, Ronan Dirr, Mounia Boulberdaa, Canan G Nebigil, Laurent Désaubry
Published 2011-01-01

Triazine-Based Small Molecules: A Potential New Class of Compounds in the Antifungal Toolbox

by Karen A. Conrad, Hyunjeong Kim, Mohammad Qasim, Amel Djehal, Aaron D. Hernday, Laurent Désaubry, Jason M. Rauceo
Published 2023-01-01

The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model

by Marina Wierz, Sandrine Pierson, Nora Chouha, Laurent Désaubry, Jean-Hugues François, Guy Berchem, Jerome Paggetti, Etienne Moussay
Published 2018-04-01

FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity.

by Rehana Qureshi, Onur Yildirim, Adeline Gasser, Christine Basmadjian, Qian Zhao, Jean-Philippe Wilmet, Laurent Désaubry, Canan G Nebigil
Published 2015-01-01

Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1.

by Adeline Gasser, Simone Brogi, Kyoji Urayama, Toshishide Nishi, Hitoshi Kurose, Andrea Tafi, Nigel Ribeiro, Laurent Désaubry, Canan G Nebigil
Published 2015-01-01

Correction: Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway

by Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Published 2022-09-01

Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway

by Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Published 2018-02-01

Correction to: Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway

by Gangjun Yuan, Xin Chen, Zhuowei Liu, Wensu Wei, Qinghai Shu, Hussein Abou-Hamdan, Lijuan Jiang, Xiangdong Li, Rixin Chen, Laurent Désaubry, Fangjian Zhou, Dan Xie
Published 2021-03-01

Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects

by Hafidha Bentayeb, Marine Aitamer, Barbara Petit, Lydie Dubanet, Sabria Elderwish, Laurent Désaubry, Armand de Gramont, Eric Raymond, Agnès Olivrie, Julie Abraham, Marie-Odile Jauberteau, Danielle Troutaud
Published 2019-11-01

eIF4A1 Is a Prognostic Marker and Actionable Target in Human Hepatocellular Carcinoma

by Sara M. Steinmann, Anabel Sánchez-Martín, Elisabeth Tanzer, Antonio Cigliano, Giovanni M. Pes, Maria M. Simile, Laurent Desaubry, Jose J.G. Marin, Matthias Evert, Diego F. Calvisi
Published 2023-01-01

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity.

by Maxime G Blanchard, Jeroen H F de Baaij, Sjoerd A J Verkaart, Anke L Lameris, Christine Basmadjian, Qian Zhao, Laurent Désaubry, René J M Bindels, Joost G J Hoenderop
Published 2015-01-01

Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

by Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Published 2020-08-01

Non-classical ferroptosis inhibition by a small molecule targeting PHB2

by Wei Yang, Bo Mu, Jing You, Chenyu Tian, Huachao Bin, Zhiqiang Xu, Liting Zhang, Ronggang Ma, Ming Wu, Guo Zhang, Chong Huang, Linli Li, Zhenhua Shao, Lunzhi Dai, Laurent Désaubry, Shengyong Yang
Published 2022-12-01