Targeting heparan sulfate-protein interactions with oligosaccharides and monoclonal antibodies

by Miaomiao Li, Lars C. Pedersen, Ding Xu
Published 2023-05-01

Structural Insights into the Specificity of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Family X DNA Polymerases

by Andrea M. Kaminski, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek
Published 2021-12-01

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break

by Andrea M. Kaminski, John M. Pryor, Dale A. Ramsden, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek
Published 2020-09-01

Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining

by Andrea M. Kaminski, Kishore K. Chiruvella, Dale A. Ramsden, Katarzyna Bebenek, Thomas A. Kunkel, Lars C. Pedersen
Published 2022-07-01

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

by Da-Yun Jin, Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford, Jian-Ke Tie
Published 2023-02-01

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

by Yin Luo, Huanmeng Hao, Zhangjie Wang, Chih Yean Ong, Robert Dutcher, Yongmei Xu, Jian Liu, Lars C Pedersen, Ding Xu
Published 2024-01-01

Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase

by Thomas W. Kirby, Scott A. Gabel, Eugene F. DeRose, Lalith Perera, Juno M. Krahn, Lars C. Pedersen, Robert E. London
Published 2023-11-01

Editorial: Heparan sulfate-binding proteins in health and disease

by Lauren A. Gandy, Lauren A. Gandy, Fuming Zhang, Ding Xu, Lars C. Pedersen, Kay Grobe, Chunyu Wang, Chunyu Wang, Chunyu Wang
Published 2024-03-01

Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7

by Jungki Min, Alexander C. Y. Foo, Scott A. Gabel, Lalith Perera, Eugene F. DeRose, Anna Pomés, Lars C. Pedersen, Geoffrey A. Mueller
Published 2023-03-01

Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis

by Andrea M. Kaminski, Percy P. Tumbale, Matthew J. Schellenberg, R. Scott Williams, Jason G. Williams, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek
Published 2018-07-01

Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

by Joonas A. Jamsen, William A. Beard, Lars C. Pedersen, David D. Shock, Andrea F. Moon, Juno M. Krahn, Katarzyna Bebenek, Thomas A. Kunkel, Samuel H. Wilson
Published 2017-08-01

Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy

by Nicole A. LaHood, Jungki Min, Tarun Keswani, Crystal M. Richardson, Kwasi Amoako, Jingjia Zhou, Orlee Marini-Rapoport, Hervé Bernard, Stéphane Hazebrouck, Wayne G. Shreffler, J. Christopher Love, Anna Pomes, Lars C. Pedersen, Geoffrey A. Mueller, Sarita U. Patil
Published 2023-02-01