Pro-arrhythmic role of adrenergic spatial densities in the human atria: An in-silico study.

by Karl Magtibay, Stéphane Massé, Kumaraswamy Nanthakumar, Karthikeyan Umapathy
Published 2023-01-01

Decrement Evoked Potential Mapping to Guide Ventricular Tachycardia Ablation: Elucidating the Functional Substrate

by Abhishek Bhaskaran, John Fitzgerald, Nicholas Jackson, Sigfus Gizurarson, Kumaraswamy Nanthakumar, Andreu Porta-Sánchez
Published 2020-12-01

Overdrive pacing in the acute management of osimertinib-induced ventricular arrhythmias: A case report and literature review

by Yanyu Zhang, Yanyu Zhang, Xingtong Wang, Yilin Pan, Beibei Du, Kumaraswamy Nanthakumar, Ping Yang
Published 2022-09-01

Microvolt QRS Alternans Without Microvolt T‐Wave Alternans in Human Cardiomyopathy: A Novel Risk Marker of Late Ventricular Arrhythmias

by Adrian Suszko, Sachin Nayyar, Christopher Labos, Kumaraswamy Nanthakumar, Arnold Pinter, Eugene Crystal, Vijay S. Chauhan
Published 2020-09-01

Heart rate in patients with reduced ejection fraction: relationship between single time point measurement and mean heart rate on prolonged implantable cardioverter defibrillator mo...

by Marlena V. Habal, Kumaraswamy Nanthakumar, Peter C. Austin, Cassandra Freitas, Christopher Labos, Douglas S. Lee
Published 2018-01-01

Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review

by Andreu Porta‐Sánchez, Cameron Gilbert, Danna Spears, Eitan Amir, Joyce Chan, Kumaraswamy Nanthakumar, Paaladinesh Thavendiranathan
Published 2017-12-01

ILK induces cardiomyogenesis in the human heart.

by Alexandra Traister, Shabana Aafaqi, Stephane Masse, Xiaojing Dai, Mark Li, Aleksander Hinek, Kumaraswamy Nanthakumar, Gregory Hannigan, John G Coles
Published 2012-01-01

Mortality Implications of Appropriate Implantable Cardioverter Defibrillator Therapy in Secondary Prevention Patients: Contrasting Mortality in Primary Prevention Patients From a P...

by Fahad Almehmadi, Andreu Porta‐Sánchez, Andrew C. T. Ha, Hadas D. Fischer, Xuesong Wang, Peter C. Austin, Douglas S. Lee, Kumaraswamy Nanthakumar
Published 2017-08-01

Arrhythmogenic Ventricular Remodeling by Next-Generation Bruton’s Tyrosine Kinase Inhibitor Acalabrutinib

by Yanan Zhao, Praloy Chakraborty, Julianna Tomassetti, Tasnia Subha, Stéphane Massé, Paaladinesh Thavendiranathan, Filio Billia, Patrick F. H. Lai, Husam Abdel-Qadir, Kumaraswamy Nanthakumar
Published 2024-06-01

Impaired Cardiac AMPK (5′‐Adenosine Monophosphate‐Activated Protein Kinase) and Ca2+‐Handling, and Action Potential Duration Heterogeneity in Ibrutinib‐Induced Ventricular Arrhythm...

by Yanan Zhao, Beibei Du, Praloy Chakraborty, Nathan Denham, Stéphane Massé, Patrick F.H. Lai, Mohammed Ali Azam, Filio Billia, Paaladinesh Thavendiranathan, Husam Abdel‐Qadir, Gary D. Lopaschuk, Kumaraswamy Nanthakumar
Published 2024-06-01

Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms

by Karl Magtibay, Stéphane Massé, John Asta, Marjan Kusha, Patrick F. H. Lai, Mohammed Ali Azam, Andreu Porta‐Sanchez, Shouvik Haldar, Daniel Malebranche, Christopher Labos, D. Curtis Deno, Kumaraswamy Nanthakumar
Published 2017-08-01

IL-6 and D-dimer Levels at Admission Predict Cardiac Injury and Early Mortality during SARS-CoV-2 Infection

by Kexin Peng, Beibei Du, Daoyuan Si, Lina Jin, Bo Yang, Neil Johnson, Lujia Ni, Qian Zhang, Mohammed Ali Azam, Patrick F. H. Lai, Slava Epelman, Kumaraswamy Nanthakumar, Ping Yang
Published 2024-01-01

Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.

by Gopal Sivagangabalan, Hamed Nazzari, Olivier Bignolais, Ange Maguy, Patrice Naud, Talha Farid, Stéphane Massé, Nathalie Gaborit, Andras Varro, Krishnakumar Nair, Peter Backx, Edward Vigmond, Stanley Nattel, Sophie Demolombe, Kumaraswamy Nanthakumar
Published 2014-01-01

TMEM43 mutation p.S358L alters intercalated disc protein expression and reduces conduction velocity in arrhythmogenic right ventricular cardiomyopathy.

by Vinayakumar Siragam, Xuezhi Cui, Stephane Masse, Cameron Ackerley, Shabana Aafaqi, Linn Strandberg, Michael Tropak, Michael D Fridman, Kumaraswamy Nanthakumar, Jun Liu, Yu Sun, Bin Su, Caroline Wang, Xiaoru Liu, Yuqing Yan, Ariel Mendlowitz, Robert M Hamilton
Published 2014-01-01

Statins Protect Against Early Stages of Doxorubicin-induced Cardiotoxicity Through the Regulation of Akt Signaling and SERCA2

by Keith Dadson, PhD, Paaladinesh Thavendiranathan, MD, SM, Ludger Hauck, PhD, Daniela Grothe, Mohammed Ali Azam, MBBS, PhD, Shanna Stanley-Hasnain, MSc, Donya Mahiny-Shahmohammady, BSc, Daoyuan Si, MD, PhD, Mahmoud Bokhari, MD, Patrick F.H. Lai, MSc, Stéphane Massé, MASc, Kumaraswamy Nanthakumar, MD, Filio Billia, MD, PhD
Published 2022-12-01

Cardioprotective effects of dantrolene in doxorubicin-induced cardiomyopathy in mice

by Mohammed Ali Azam, MBBS, PhD, Praloy Chakraborty, MD, Mahmoud M. Bokhari, MBBS, Keith Dadson, PhD, Beibei Du, MD, PhD, Stéphane Massé, MASc, Daoyuan Si, MD, PhD, Ahmed Niri, BEng, Arjun K. Aggarwal, Patrick F.H. Lai, MSc, Sheila Riazi, MD, MSc, Filio Billia, MD, PhD, Kumaraswamy Nanthakumar, MD
Published 2021-12-01

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias

by Rocco Romagnuolo, Hassan Masoudpour, Andreu Porta-Sánchez, Beiping Qiang, Jennifer Barry, Andrew Laskary, Xiuling Qi, Stéphane Massé, Karl Magtibay, Hiroyuki Kawajiri, Jun Wu, Tamilla Valdman Sadikov, Janet Rothberg, Krishna M. Panchalingam, Emily Titus, Ren-Ke Li, Peter W. Zandstra, Graham A. Wright, Kumaraswamy Nanthakumar, Nilesh R. Ghugre, Gordon Keller, Michael A. Laflamme
Published 2019-05-01

The validity of current implantable cardioverter-defibrillator guidelines in a real-world population of adults with congenital heart disease: A single-center experience

by Satoshi Kawada, MD, PhD, Praloy Chakraborty, DM, FACC, Jared Nanthakumar, Lisa Albertini, MD, Erwin N. Oechslin, MD, Susan Lucy Roche, MD, Candice Silversides, MD, Rachel M. Wald, MD, Eugene Downar, MD, Louise Harris, MD, Lorna Swan, MD, Rafael Alonso-Gonzalez, MD, Sara Thorne, MD, Kumaraswamy Nanthakumar, MD, Blandine Mondésert, MD, Paul Khairy, MD, PhD, Krishnakumar Nair, DM
Published 2022-06-01

The Role of Ablation in Prevention of Recurrent Implantable Cardioverter Defibrillator Shocks in Patients With Tetralogy of Fallot

by Satoshi Kawada, MD, PhD, Praloy Chakraborty, MD, FACC, Eugene Downar, MD, Andreu-Porta Sanchez, MD, PhD, Gnalini Sathananthan, MD, Abhishek Bhaskaran, MD, PhD, Priyanka Kugamoorthy, MD, Lisa Albertini, MD, Erwin N. Oechslin, MD, Candice Silversides, MD, Rachel M. Wald, MD, Susan Lucy Roche, MD, Lorna Swan, MD, Rafael Alonso-Gonzalez, MD, Sara Thorne, MD, Louise Harris, MD, Edward Hickey, MBBS, Kumaraswamy Nanthakumar, MD, Blandine Mondésert, MD, Paul Khairy, MD, PhD, Krishnakumar Nair, MD
Published 2021-05-01