GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

by Christina Wolf, Alireza Pouya, Sara Bitar, Annika Pfeiffer, Diones Bueno, Liliana Rojas-Charry, Sabine Arndt, David Gomez-Zepeda, Stefan Tenzer, Federica Dal Bello, Caterina Vianello, Sandra Ritz, Jonas Schwirz, Kristina Dobrindt, Michael Peitz, Eva-Maria Hanschmann, Pauline Mencke, Ibrahim Boussaad, Marion Silies, Oliver Brüstle, Marta Giacomello, Rejko Krüger, Axel Methner
Published 2022-06-01

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility

by Georgios Voloudakis, James M. Vicari, Sanan Venkatesh, Gabriel E. Hoffman, Kristina Dobrindt, Wen Zhang, Noam D. Beckmann, Christina A. Higgins, Stathis Argyriou, Shan Jiang, Daisy Hoagland, Lina Gao, André Corvelo, Kelly Cho, Kyung Min Lee, Jiantao Bian, Jennifer S. Lee, Sudha K. Iyengar, Shiuh-Wen Luoh, Schahram Akbarian, Robert Striker, Themistocles L. Assimes, Eric E. Schadt, Julie A. Lynch, Miriam Merad, Benjamin R. tenOever, Alexander W. Charney, Mount Sinai COVID-19 Biobank, VA Million Veteran Program COVID-19 Science Initiative, Kristen J. Brennand, John F. Fullard, Panos Roussos
Published 2022-09-01