Crosstalk Between the NLRP3 Inflammasome/ASC Speck and Amyloid Protein Aggregates Drives Disease Progression in Alzheimer’s and Parkinson’s Disease

by Jonathan Hulse, Kiran Bhaskar, Kiran Bhaskar
Published 2022-02-01

Editorial: Innate immunity and neurodegenerative diseases – triggers from self and non-self

by Jonathan Hulse, Adam Bachstetter, Surojit Paul, Kiran Bhaskar, Kiran Bhaskar
Published 2023-06-01

Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy

by Shanya Jiang, Kiran Bhaskar
Published 2020-10-01

Apoptosis-associated speck-like protein containing a CARD-mediated release of matrix metalloproteinase 10 stimulates a change in microglia phenotype

by Kathryn E. Sánchez, Kiran Bhaskar, Kiran Bhaskar, Gary A. Rosenberg, Gary A. Rosenberg
Published 2022-10-01

Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons.

by Jessica L Binder, Praveen Chander, Vojo Deretic, Jason P Weick, Kiran Bhaskar
Published 2020-01-01

Interleukin-10 deficiency exacerbates inflammation-induced tau pathology

by Lea L. Weston, Shanya Jiang, Devon Chisholm, Lauren L. Jantzie, Kiran Bhaskar
Published 2021-07-01

Data-Driven Thermal Anomaly Detection in Large Battery Packs

by Kiran Bhaskar, Ajith Kumar, James Bunce, Jacob Pressman, Neil Burkell, Christopher D. Rahn
Published 2023-01-01

Non-invasive vagus nerve stimulation reduced neuron-derived IL-1β and neuroinflammation in acute ischemic rat brain

by Lisa Y. Yang, Kiran Bhaskar, Jeffrey Thompson, Kelsey Duval, Michel Torbey, Yi Yang
Published 2022-06-01

Protocol to measure apoptosis-associated speck-like protein containing a CARD specks in human cerebrospinal fluid via imaging flow cytometry

by Kathryn E. Sánchez, Shanya Jiang, Sharina Palencia Desai, Jeffery Thompson, Sasha Hobson, Gary A. Rosenberg, Kiran Bhaskar
Published 2024-03-01

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

by Kiran Bhaskar, Nicole Maphis, Guixiang Xu, Nicholas H. Varvel, Olga N. Kokiko-Cochran, Jason P. Weick, Susan M. Staugaitis, Astrid Cardona, Richard M. Ransohoff, Karl Herrup, Bruce T. Lamb
Published 2014-02-01

Machine learning prediction and tau-based screening identifies potential Alzheimer’s disease genes relevant to immunity

by Jessica Binder, Oleg Ursu, Cristian Bologa, Shanya Jiang, Nicole Maphis, Somayeh Dadras, Devon Chisholm, Jason Weick, Orrin Myers, Praveen Kumar, Jeremy J. Yang, Kiran Bhaskar, Tudor I. Oprea
Published 2022-02-01

Selective In Vitro and Ex Vivo Staining of Brain Neurofibrillary Tangles and Amyloid Plaques by Novel Ethylene Ethynylene-Based Optical Sensors

by Florencia A. Monge, Adeline M. Fanni, Patrick L. Donabedian, Jonathan Hulse, Nicole M. Maphis, Shanya Jiang, Tia N. Donaldson, Benjamin J. Clark, David G. Whitten, Kiran Bhaskar, Eva Y. Chi
Published 2023-01-01

Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction

by Limor Raz, Kiran Bhaskar, John Weaver, Sandro Marini, Quanguang Zhang, Jeffery F. Thompson, Candice Espinoza, Sulaiman Iqbal, Nicole M. Maphis, Lea Weston, Laurel O. Sillerud, Arvind Caprihan, John C. Pesko, Erik B. Erhardt, Gary A. Rosenberg
Published 2019-06-01

Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice

by David Scieszka, Yan Jin, Shahani Noor, Ed Barr, Marcus Garcia, Jessica Begay, Guy Herbert, Russell P. Hunter, Kiran Bhaskar, Rahul Kumar, Rama Gullapalli, Alicia Bolt, Mark A. McCormick, Barry Bleske, Haiwei Gu, Matthew J. Campen
Published 2023-08-01

Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy

by Shane M. Bemiller, Nicole M. Maphis, Shane V. Formica, Gina N. Wilson, Crystal M. Miller, Guixiang Xu, Olga N. Kokiko-Cochran, Ki-Wook Kim, Steffen Jung, Judy L. Cannon, Samuel D. Crish, Astrid E. Cardona, Bruce T. Lamb, Kiran Bhaskar
Published 2018-09-01

Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

by Shanya Jiang, Nicole M. Maphis, Jessica Binder, Devon Chisholm, Lea Weston, Walter Duran, Crina Peterson, Amber Zimmerman, Michael A. Mandell, Stephen D. Jett, Eileen Bigio, Changiz Geula, Nikolaos Mellios, Jason P. Weick, Gary A. Rosenberg, Eicke Latz, Michael T. Heneka, Kiran Bhaskar
Published 2021-09-01