Immunothrombosis and thromboinflammation in host defense and disease

by Kimberly Martinod, Carsten Deppermann
Published 2021-04-01

Solid peripheral tumor leads to systemic inflammation, astrocyte activation and signs of behavioral despair in mice.

by Melanie Demers, Georgette L Suidan, Nick Andrews, Kimberly Martinod, Jessica E Cabral, Denisa D Wagner
Published 2018-01-01

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice

by Thilo Witsch, Kimberly Martinod, Nicoletta Sorvillo, Irina Portier, Simon F. De Meyer, Denisa D. Wagner
Published 2018-02-01

Neutrophil extracellular trap biomarkers in aneurysmal subarachnoid hemorrhage: early decline of DNase 1 activity associated with delayed cerebral ischemia

by Philipp Hendrix, Philipp Hendrix, Jens Witsch, Valérie Spalart, Hauke Schneider, Joachim Oertel, Jürgen Geisel, Kimberly Martinod, Sina Hemmer
Published 2024-04-01

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

by Naamah L. Zitomersky, Melanie Demers, Kimberly Martinod, Maureen Gallant, Stephen M. Cifuni, Amlan Biswas, Scott Snapper, Denisa D. Wagner
Published 2017-06-01

The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice

by Frederik Denorme, Kimberly Martinod, Aline Vandenbulcke, Cécile V. Denis, Peter J. Lenting, Hans Deckmyn, Karen Vanhoorelbeke, Simon F. De Meyer
Published 2020-02-01

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice.

by Hideki Hayashi, Deya Cherpokova, Kimberly Martinod, Thilo Witsch, Siu Ling Wong, Maureen Gallant, Stephen M Cifuni, Leonard P Guarente, Denisa D Wagner
Published 2017-01-01

Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

by Jens Witsch, MD, Valérie Spalart, MD, Kimberly Martinod, PhD, Hauke Schneider, MD, MBA, Joachim Oertel, MD, Jürgen Geisel, MD, Philipp Hendrix, MD, Sina Hemmer, MD
Published 2022-05-01

Thromboprophylaxis in COVID‐19: Weight and severity adjusted intensified dosing

by Matthias M. Engelen, Christophe Vandenbriele, Valérie Spalart, Caroline P. Martens, Bert Vandenberk, Pieter Sinonquel, Natalie Lorent, Paul De Munter, Rik Willems, Joost Wauters, Alexander Wilmer, Dieter Dauwe, Jan Gunst, Ipek Guler, Stefan Janssens, Kimberly Martinod, Griet Pieters, Kathelijne Peerlinck, Peter Verhamme, Thomas Vanassche
Published 2022-03-01

OTULIN haploinsufficiency predisposes to environmentally directed inflammation

by Frederik Staels, Frederik Staels, Leoni Bücken, Leana De Vuyst, Mathijs Willemsen, Erika Van Nieuwenhove, Margaux Gerbaux, Julika Neumann, Julika Neumann, Vanshika Malviya, Lize Van Meerbeeck, Jeason Haughton, Laura Seldeslachts, Mieke Gouwy, Kimberly Martinod, Greetje Vande Velde, Paul Proost, Lidia Yshii, Susan Schlenner, Rik Schrijvers, Rik Schrijvers, Rik Schrijvers, Adrian Liston, Stephanie Humblet-Baron
Published 2024-05-01

SARS-CoV-2 infection causes prolonged cardiomyocyte swelling and inhibition of HIF1α translocation in an animal model COVID-19

by Margo Daems, Laurens Liesenborghs, Laurens Liesenborghs, Robbert Boudewijns, Steven J. Simmonds, Sirima Kraisin, Jore Van Wauwe, Ilona Cuijpers, Ilona Cuijpers, Jana Raman, Nadèche Geuens, Tina Van Buyten, Marleen Lox, Peter Verhamme, Sophie Van Linthout, Sophie Van Linthout, Kimberly Martinod, Stephane Heymans, Stephane Heymans, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Johan Neyts, Elizabeth A. V. Jones, Elizabeth A. V. Jones
Published 2022-10-01

Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates

by Bert Malengier-Devlies, Jessica Filtjens, Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Greet Hermans, Philippe Meersseman, Alexander Wilmer, Mieke Gouwy, Abhishek D. Garg, Stephanie Humblet-Baron, Frederik De Smet, Kimberly Martinod, Els Wauters, Paul Proost, Carine Wouters, Georges Leclercq, Diether Lambrechts, Joost Wauters, Patrick Matthys
Published 2022-10-01

Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19

by Caroline P. Martens, Pierre Van Mol, Joost Wauters, Els Wauters, Tanja Gangnus, Bernard Noppen, Hanne Callewaert, Jean H.M. Feyen, Laurens Liesenborghs, Elisabeth Heylen, Sander Jansen, Leydi Carolina Velásquez Pereira, Sirima Kraisin, Ipek Guler, Matthias M. Engelen, Anna Ockerman, Anke Van Herck, Robin Vos, Christophe Vandenbriele, Philippe Meersseman, Greet Hermans, Alexander Wilmer, Kimberly Martinod, Bjoern B. Burckhardt, Marc Vanhove, Marc Jacquemin, Peter Verhamme, Johan Neyts, Thomas Vanassche
Published 2022-09-01

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

by Serhan, Charles N., Yang, Rong, Martinod, Kimberly, Kasuga, Kie, Pillai, Padmini S., Porter, Timothy F., Oh, Sungwhan F., Spite, Matthew
Published 2019

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice

by Witsch, Thilo, Martinod, Kimberly, Sorvillo, Nicoletta, Portier, Irina, De Meyer, Simon F., Wagner, Denisa D.
Published 2018

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice

by Hayashi, Hideki, Cherpokova, Deya, Martinod, Kimberly, Witsch, Thilo, Wong, Siu Ling, Gallant, Maureen, Cifuni, Stephen M., Guarente, Leonard P., Wagner, Denisa D.
Published 2018