Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors

by Kay-Uwe Wagner
Published 2022-06-01

Cellular Plasticity in Mammary Gland Development and Breast Cancer

by Madison N. Wicker, Kay-Uwe Wagner
Published 2023-11-01

A Mammary-Specific, Long-range Deletion on Mouse Chromosome 11 Accelerates Brca1-Associated Mammary Tumorigenesis

by Aleata A. Triplett, Cristina Montagna, Kay-Uwe Wagner
Published 2008-12-01

Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary gland.

by Kazuhito Sakamoto, Jeffrey W Schmidt, Kay-Uwe Wagner
Published 2012-01-01

Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation

by Hyunji Byun, Sojung Kwon, Kay-Uwe Wagner, Hyejin Shin, Hyunjung Jade Lim
Published 2021-07-01

Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

by Jean Grisouard, Hui Hao-Shen, Stephan Dirnhofer, Kay-Uwe Wagner, Radek C. Skoda
Published 2014-04-01

Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers

by Nirakar Rajbhandari, Wan-chi Lin, Barbara L. Wehde, Aleata A. Triplett, Kay-Uwe Wagner
Published 2017-02-01

The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease

by Rosa-Maria Ferraiuolo, Karoline C. Manthey, Marissa J. Stanton, Aleata A. Triplett, Kay-Uwe Wagner
Published 2020-02-01

IRF4 is a suppressor of c-Myc induced B cell leukemia.

by Simanta Pathak, Shibin Ma, Long Trinh, James Eudy, Kay-Uwe Wagner, Shantaram S Joshi, Runqing Lu
Published 2011-01-01

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

by Wan-chi Lin, Jeffrey W Schmidt, Bradley A Creamer, Aleata A Triplett, Kay-uwe Wagner
Published 2013-01-01

Targeting Gi/o protein–coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy

by Cancan Lyu, Yuanchao Ye, Maddison M. Lensing, Kay-Uwe Wagner, Ronald J. Weigel, Songhai Chen
Published 2021-09-01

A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death.

by Chantey R Morris, Marissa J Stanton, Karoline C Manthey, Keon Bong Oh, Kay-Uwe Wagner
Published 2012-01-01

Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

by Barbara L. Wehde, Patrick D. Rädler, Hridaya Shrestha, Stevi J. Johnson, Aleata A. Triplett, Kay-Uwe Wagner
Published 2018-11-01

Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside

by Md. Hafiz Uddin, Mohammed Najeeb Al-Hallak, Philip A. Philip, Ramzi M. Mohammad, Nerissa Viola, Kay-Uwe Wagner, Asfar S. Azmi
Published 2021-06-01

Dual recombinase action in the normal and neoplastic mammary gland epithelium

by Patrick D. Rädler, Kerry Vistisen, Aleata A. Triplett, Rayane Dennaoui, Yong Li, Hridaya Shrestha, Rosa-Maria Ferraiuolo, Amalraj Thangasamy, Dieter Saur, Kay-Uwe Wagner
Published 2021-10-01

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.

by Sung O Park, Heather L Wamsley, Kyungmi Bae, Zhongbo Hu, Xiaomiao Li, Se-woon Choe, William B Slayton, S Paul Oh, Kay-Uwe Wagner, Peter P Sayeski
Published 2013-01-01

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

by Patrick D. Rädler, Barbara L. Wehde, Aleata A. Triplett, Hridaya Shrestha, Jonathan H. Shepherd, Adam D. Pfefferle, Hallgeir Rui, Robert D. Cardiff, Charles M. Perou, Kay-Uwe Wagner
Published 2021-06-01

The Janus kinase 1 is critical for pancreatic cancer initiation and progression

by Hridaya Shrestha, Patrick D. Rädler, Rayane Dennaoui, Madison N. Wicker, Nirakar Rajbhandari, Yunguang Sun, Amy R. Peck, Kerry Vistisen, Aleata A. Triplett, Rafic Beydoun, Esta Sterneck, Dieter Saur, Hallgeir Rui, Kay-Uwe Wagner
Published 2024-05-01

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

by Harsh R. Desai, Tharini Sivasubramaniyam, Xavier S. Revelo, Stephanie A. Schroer, Cynthia T. Luk, Prashanth R. Rikkala, Adam H. Metherel, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Joshua A. Rapps, Rickvinder Besla, Clinton S. Robbins, Kay-Uwe Wagner, Richard P. Bazinet, Daniel A. Winer, Minna Woo
Published 2017-08-01

Identification of actionable targets for breast cancer intervention using a diversity outbred mouse model

by Jennifer B. Jacob, Kuang-Chung Wei, Gerold Bepler, Joyce D. Reyes, Andi Cani, Lisa Polin, Kathryn White, Seongho Kim, Nerissa Viola, Julie McGrath, Anthony Guastella, CongCong Yin, Qing-Shen Mi, Benjamin L. Kidder, Kay-Uwe Wagner, Stuart Ratner, Victoria Phillips, Joanne Xiu, Prahlad Parajuli, Wei-Zen Wei
Published 2023-04-01